Results 101 to 110 of about 4,189,896 (296)

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

open access: yesFEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

open access: yesFEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng   +8 more
wiley   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

open access: yesFEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Design and Realization of Loaded- and Reflect-Line X-band RF MEMS Phase Shifters

open access: yes, 2010
The paper presents some experimental results obtained for RF-MEMS phase shifters in X-band. Two different phase shifters are considered: a loaded-line and a reflect-line phase shifter.
B. Margesin   +8 more
core   +1 more source

Butler Matrix Based on Substrate Integrated Waveguide Without Crossover and Phase Shifter for Millimeter Waves Applications [version 2; peer review: 1 approved, 2 approved with reservations]

open access: yesF1000Research
Background A novel low-loss 4 × 4 Butler Matrix structure for 26 GHz operation is designed in this study. The proposed 4 × 4 antenna Butler matrix comprises an inscribed structure, which makes it fundamentally different from traditional beam-forming ...
Zahriladha Zakaria   +5 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

The investigation of gyroelectric n-InAs phase shifters characteristics

open access: yes, 2012
In this paper the open cylindrical gyroelectric phase shifters characteristics are investigated. The investigation is performed by changing their parameters: the magnetic flux density, the number of layers of dielectric, width and permittivities.
Mališauskas, Vacius, Plonis, Darius
core  

E-Band Beam-Steerable and Scalable Phased Antenna Array for 5G Access Point

open access: yesInternational Journal of Antennas and Propagation, 2018
This paper presents a new implementation of the beam-steerable two-dimensional phased antenna array for the forthcoming 5G networks. The antenna enables easy integration of phase shifters and other active electronics on a single PCB, low-loss feed ...
Md. Mazidul Islam   +6 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

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