Results 41 to 50 of about 153,856 (313)

Parent Quality of Life at Two Years Following Their Child's Completion of Acute Lymphoblastic Leukemia Treatment

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Parents of children treated for acute lymphoblastic leukemia (ALL) often experience significant caregiver burden and disruption to their well‐being. While parent quality of life (QoL) during treatment is well characterized, little is known about outcomes during early survivorship.
Sara Dal Pra   +3 more
wiley   +1 more source

Timing of growth affected broiler breeder feeding motivation and reproductive traits

open access: yesPoultry Science, 2021
: The amount and timing of growth are important factors that affect age at first egg, body conformation, reproductive performance, and hunger in broiler breeders.
Mohammad Afrouziyeh   +2 more
doaj   +1 more source

Dimension of Phase Point Trajectory

open access: yesInternational Journal of Modern Nonlinear Theory and Application, 2015
In a physical system, phase point trajectory is impossible to be space-filling curve, of which the dimension is not greater than one. Equipotential map concept is proposed. When phase point trajectory dimension is 0, calculus tool is no longer applicable. System state can be changed instantly.
openaire   +2 more sources

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Математическое моделирование автоколебаний нейрона в клеточной мембране с использованием дробной модели ФитцХью-Нагумо с функцией интенсивности раздражителя

open access: yesVestnik KRAUNC: Fiziko-Matematičeskie Nauki
В статье проводится исследование процесса временного распространения нервного импульса в клеточной мембране. Для этой цели была предложена новая математическая модель, основанная на дробном осцилляторе ФитцХью-Нагумо с функцией интенсивности раздражителя.
Алимова, Н.Б.
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Stratifications and foliations in phase portraits of gene network models

open access: yesВавиловский журнал генетики и селекции, 2023
Periodic processes of gene network functioning are described with good precision by periodic trajectories (limit cycles) of multidimensional systems of kinetic-type differential equations.
V. P. Golubyatnikov   +3 more
doaj   +1 more source

Erythrocyte morphological states, phases, transitions and trajectories

open access: yesBiochimica et Biophysica Acta (BBA) - Biomembranes, 2010
Morphological response (MR) of red blood cells represents a triphasic sequence of spontaneously occurring shape transformation between different shape states upon transfer the cells into isotonic sucrose solution in the order: S(0) (initial discoid shape in physiological saline)-->S(1) (echinocytic shape at the beginning of MR, phase 1)-->S(2 ...
openaire   +2 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

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