Results 111 to 120 of about 116,811 (268)

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Phase Transformations in Amorphous Solids

High Temperature Materials and Processes, 1994
Stoch, L., Waclawska, I.
doaj   +1 more source

Pressure-Induced Phase Transformations of Quasi-2D Sr₃Hf₂O₇. [PDF]

J Phys Chem C Nanomater Interfaces, 2023
Barbosa MCB, da Silva EL, Lekshmi PN, Marcondes ML, Assali LVC, Petrilli HM, Lopes AML, Araújo JP.   +7 more
europepmc   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Sub-Ångström Three-Dimensional Electron Diffraction Reveals Crystal Structures and Phase Transformations in Liquids. [PDF]

J Am Chem Soc
Wang H, Lajer J, Broadhurst ET, Malik T, Yesibolati MN, Jensen ECS, Mølhave KS, Xu H, Zou X.   +8 more
europepmc   +1 more source

Weakening the nuclear envelope: Lamin B receptor in melanoma metastasis

Molecular Oncology, EarlyView.
LBR‐driven nuclear fragility supports melanoma invasion. A: Melanocyte presents low LBR (Lamin B Receptor) levels, maintaining nuclear integrity and lamina‐chromatin tethering. B: During malignant progression, upregulation of LBR clusters at the INM (Inner Nuclear Membrane) during confined migration causes local lamina weakening and cholesterol ...
Francesca Lorenzini, Maria Caterina Mione   +1 more
wiley   +1 more source

On the orientation dependence of ion-induced phase transformations in austenitic stainless steel. [PDF]

J Mater Sci
Whiteside J, Whiting MJ, Cox DC, Hobler G.   +3 more
europepmc   +1 more source

Magnetocaloric Effect, Structure, Spinodal Decomposition and Phase Transformations Heusler Alloy Ni-Mn-In. [PDF]

Nanomaterials (Basel), 2023
Kuznetsov DD, Kuznetsova EI, Mashirov AV, Loshachenko AS, Danilov DV, Mitsiuk VI, Kuznetsov AS, Shavrov VG, Koledov VV, Ari-Gur P.   +9 more
europepmc   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Dissolving alloying additions inside precipitates of lightweight alloys to promote phase transformations [PDF]

BIO Web of Conferences
Bourgeois Laure, Su Shenghan, Weyland Matthew, Abian Loreibelle, Li Jiehua, Nakashima Philip, Medhekar Nikhil   +6 more
doaj   +1 more source