Results 121 to 130 of about 11,437,855 (347)

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source

Electroweak phase transition in technicolor

, 2010
Several phenomenologically viable walking technicolor models have been proposed recently. I demonstrate that these models can have first order electroweak phase transitions, which are sufficiently strong for electroweak baryogenesis.
Arnold P, Bender P L, Cline J M, Harry G M, Harry G M, Huber S J, Järvinen M, Matti Järvinen, Sannino F   +8 more
core   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source

Topological Phase Transition-Induced Triaxial Vector Magnetoresistance in (Bi_1–xIn_x)₂Se₃ Nanodevices [PDF]

, 2018
Minhao Zhang, Huaiqiang Wang, Kejun Mu, Pengdong Wang, Wei Niu, Shuai Zhang, Guiling Xiao, Yequan Chen, Tong Tong, Dongzhi Fu, Xuefeng Wang, Haijun Zhang, Fengqi Song, Feng Miao, Zhe Sun, Zhengcai Xia, Xinran Wang, Yongbing Xu, Baigeng Wang, Dingyu Xing, Rong Zhang   +20 more
openalex   +1 more source

Phase Transition and Strong Predictability

, 2013
The statistical mechanical interpretation of algorithmic information theory (AIT, for short) was introduced and developed in our former work [K. Tadaki, Local Proceedings of CiE 2008, pp.425-434, 2008], where we introduced the notion of thermodynamic ...
A. Nies, C.S. Calude, C.S. Calude, G.J. Chaitin, G.J. Chaitin, K. Tadaki, L.A. Levin, M. Toda, O. Goldreich, R.G. Downey   +9 more
core   +1 more source

A steep-slope transistor based on abrupt electronic phase transition

Nature Communications, 2015
Collective interactions in functional materials can enable novel macroscopic properties like insulator-to-metal transitions. While implementing such materials into field-effect-transistor technology can potentially augment current state-of-the-art ...
N. Shukla, Arun V. Thathachary, A. Agrawal, H. Paik, A. Aziz, D. Schlom, S. Gupta, R. Engel-Herbert, S. Datta   +8 more
semanticscholar   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

Molecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani, Gilgi Friedlander, Gili Perry, Nora Balint‐Lahat, Shlomit Gilad, Dana Morzaev‐Sulzbach, Anjana Shenoy, Noa Bossel Ben‐Moshe, Anya Pavlovsky, Rinat Bernstein‐Molho, Eytan Domany, Iris Barshack, Tamar Geiger, Bella Kaufman, Einav Nili Gal‐Yam   +14 more
wiley   +1 more source

λ Phase Transition in Horava Gravity

Advances in High Energy Physics, 2018
We present another example of superfluid black hole containing λ phase transition in Horava gravity. After studying the extended thermodynamics of general dimensional Horava-Lifshitz AdS black holes, it is found that only the one with spherical horizon ...
Wei Xu
doaj   +1 more source

Expression and DNA methylation of 20S proteasome subunits as prognostic and resistance markers in cancer

Molecular Oncology, EarlyView.
Comprehensive analysis of genomic mutations, gene expression, DNA methylation, and pathway analysis of TCGA data was carried out to define cancer types in which proteasome subunits expression is associated with worse survival. Albeit the effect of specific proteasome subunits on cellular function, the main role of the proteasome is better evaluated ...
Ruba Al‐Abdulla, Simone Venz, Ruslan Al‐Ali, Martin Wendlandt, Mandy Radefeldt, Elke Krüger   +5 more
wiley   +1 more source

Nonequilibrium phase transitions in a quasi-two-dimensional superlattice with parabolic miniband [PDF]

, 2006
G. М. Shmelev, T. A. Gorshenina, É. M. Épshteǐn   +2 more
openalex   +1 more source