Results 121 to 130 of about 5,813,135 (253)

Conformal phase transition in supersymmetric QCD

open access: yesJournal of High Energy Physics
We construct a four-dimensional supersymmetric QCD in conformal window with a marginally relevant deformation which triggers the spontaneous breaking of (approximate) scale invariance and the subsequent confinement, generating a mass gap, at an energy ...
Kohei Fujikura   +4 more
doaj   +1 more source

Phase Transition in a Cell

open access: yesScience, 2009
The polarized distribution of P granules in a worm embryo is achieved, not by movement of the granules, but by a condensation process.
Le Goff, Loïc, Lecuit, Thomas
openaire   +3 more sources

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Phase Transition in Ant Colony Optimization

open access: yesPhysics
Ant colony optimization (ACO) is a stochastic optimization algorithm inspired by the foraging behavior of ants. We investigate a simplified computational model of ACO, wherein ants sequentially engage in binary decision-making tasks, leaving pheromone ...
Shintaro Mori   +3 more
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Multifunctional Phase-Transition Nanoparticles for Effective Targeted Sonodynamic-Gene Therapy Against Thyroid Papillary Carcinoma

open access: yesInternational Journal of Nanomedicine, 2023
Shihui Guan, Dengke Teng, Hui Wang,* Qimeihui Wang,* Xi Zhen, Guoqing Sui, Yang Wang, Lingyu Zhu, Yuanqiang Lin, Dan Jiao, Feng Guo Department of Ultrasound, China-Japan Union Hospital of Jilin University, Changchun, Jilin Province, 130033 ...
Guan S   +10 more
doaj  

PHASE TRANSITIONS AT INTERFACES

open access: yesLe Journal de Physique Colloques, 1989
The interface between two phases may exhibit significant structural changes if one of them comes close to a phase transition in its bulk. Surface critical phenomena, critical adsorption, and wetting phenomena, like e.g. surface melting or surface induced disorder, can occur.
openaire   +3 more sources

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

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