CDT1 is an essential protein for DNA replication licensing that loads the MCM complex, the eukaryotic replicative DNA helicase, onto replication origins. Overexpression of CDT1 induces cell cycle arrest at the S phase. Here we showed CDT1 inhibits the progression of replication forks by interacting with the MCM complex, leading to the stalling and ...
Takashi Tsuyama +7 more
wiley +1 more source
Mechanism of Carbon Diffusion and Phase-Transition-Induced FCC-TiC Formation via Hot Pressing. [PDF]
Zeng S +5 more
europepmc +1 more source
HSP70 governs permeability and mechanotransduction in primary human endothelial cells
HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez +5 more
wiley +1 more source
Polymorphism and Phase-Transition Thermodynamic Properties of Phenazone (Antipyrine). [PDF]
Bolmatenkov DN +5 more
europepmc +1 more source
Structural transition and enhanced phase transition properties of Se doped Ge2Sb2Te5 alloys [PDF]
E. M. Vinod, K. Ramesh, K. S. Sangunni
openalex +1 more source
Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays
We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul +3 more
wiley +1 more source
Topological phase transition in monolayer 1[Formula: see text]-[Formula: see text]. [PDF]
Nobahari MM, Roknabadi MR.
europepmc +1 more source
Quantum phases and transitions of bosons on a comb lattice [PDF]
Leo Radzihovsky, Emil Pellett
openalex +1 more source
Overview of molecular signatures of senescence and associated resources: pros and cons
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas +6 more
wiley +1 more source
Preparation of Temperature-Activated Nanomaterial-Enhanced Phase Transition Emulsion and Study on Self-Generating Plugging Particles. [PDF]
Wang J +8 more
europepmc +1 more source

