Results 281 to 290 of about 9,597,779 (345)

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Superior Electromechanical Power at Rare-Earth Manipulated Glassy Morphotropic Phase Transitions. [PDF]

Adv Sci (Weinh)
Zhang L, He L, Xu S, Wang H, Sun Y, Ran Y, Wang D, Chen K, Deng J, Chen Z, Wang D, Carpenter MA, Yang S.   +12 more
europepmc   +1 more source

The effect of salubrinal on the endoplasmic reticulum stress pathway in heat‐stressed spermatogonial cells in vitro

FEBS Open Bio, EarlyView.
This study investigates the protective role of salubrinal against heat‐induced endoplasmic reticulum (ER) stress in mouse spermatogenic cells (GC1 and GC2). By modulating the ER stress pathway, salubrinal alleviates cellular stress and supports spermatogenic cell survival, suggesting its potential as a therapeutic candidate for heat‐related infertility.
Suna Karadeniz Saygili, Mustafa Oztatlici, Mahmut Kemal Ozbilgin   +2 more
wiley   +1 more source

Enhanced nonlinear optical responses in two-dimensional materials via laser-induced topological phase transitions. [PDF]

Sci Rep
Azizi F, Moayeri H.
europepmc   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Decoupled few-femtosecond phase transitions in vanadium dioxide. [PDF]

Nat Commun
Brahms C, Zhang L, Shen X, Bhattacharya U, Recasens M, Osmond J, Grass T, Chhajlany RW, Hallman KA, Haglund RF, Pantelides ST, Lewenstein M, Travers JC, Johnson AS.   +13 more
europepmc   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Temperature-Induced Phase Transitions of Vivianite: In Situ Analysis of a Redox-Driven Crystallization. [PDF]

Inorg Chem
Paskin A, Couasnon T, Blukis R, Perez JPH, Reinsch S, Roddatis V, Syczewski M, Benning LG.   +7 more
europepmc   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Homometallic Intervalence Charge Transfer Band of Co(II/III) Induced by Phase Transitions in a Heterometallic Co-W Charge Transfer Photomagnet. [PDF]

Small Sci
Nakamura K, Nakabayashi K, Nosaka Y, Ota W, Kikuchi T, Ohkoshi SI.   +5 more
europepmc   +1 more source