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Phases of clinical trials: a review
A Clinical trial is a research study in human volunteers to answer specific health questions. Carefully conducted clinical trials are fastest and safest way to find treatment that work in people and way to improve health. Investigational trials determine
Venkata Reddy Samala, K. C, Venkatesh P
semanticscholar +1 more source
Could a phase model help to improve translational animal research?
Background Animal models are widely applied in medical research for different purposes. In particular, results from translational experiments may be used for subsequent clinical development.
Benjamin Mayer +2 more
doaj +1 more source
Objective: To determine the mechanism of erythropoiesis that led to anemia using the Immature Reticulocyte Fraction (IRF) parameter in various clinical phases of dengue fever.
Amaylia Oehadian +5 more
doaj +1 more source
Gendered Logics of Biomedical Research: Women in U.S. Phase I Clinical Trials [PDF]
Abstract Despite the importance of including diverse populations in biomedical research, women remain underrepresented as healthy volunteers in the testing of investigational drugs in Phase I trials. Contributing significantly to this are restrictions that pharmaceutical companies place on the participation of women of so-called ...
Fisher, Jill A, Cottingham, Marci D
openaire +3 more sources
Emotion variability and its relationship to performance is an underexplored area of research both inside and outside the realm of medical education.
Shan Li, Juan Zheng, Susanne P. Lajoie
doaj +1 more source
Application of MIDD in Clinical Research of Antitumor Drugs
The antitumor drug has become one of the focused areas in new drug research and development. Their clinical research generally consumes a long period of time, with high cost and high risk.
Mengyang YU, Hongyun WANG
doaj +1 more source
Assessment of effects of moon phases on hospital outpatient visits: An observational national study
Objectives: A vast amount of literature has been conducted for investigating the association of different lunar phases with human health; and it has mixed reviews for association and non-association of diseases with lunar phases. This study investigates
Mohy Uddin +6 more
doaj +1 more source
Asia‐inclusive global development of pevonedistat: Clinical pharmacology and translational research enabling a phase 3 multiregional clinical trial [PDF]
AbstractThe investigational NEDD8‐activating enzyme inhibitor pevonedistat is being evaluated in combination with azacitidine versus single‐agent azacitidine in patients with higher‐risk myelodysplastic syndrome (higher‐risk MDS), higher‐risk chronic myelomonocytic leukemia (higher‐risk CMML), or low‐blast acute myeloid leukemia (AML) in a Phase 3 ...
Xiaofei Zhou +13 more
openaire +3 more sources
Developing a pressure ulcer risk factor minimum data set and risk assessment framework [PDF]
AIM: To agree a draft pressure ulcer risk factor Minimum Data Set to underpin the development of a new evidenced-based Risk Assessment Framework.BACKGROUND: A recent systematic review identified the need for a pressure ulcer risk factor Minimum Data Set ...
Bader, Dan L +19 more
core +6 more sources
Background Over the past 30 years, the healthcare industry has increasingly turned its attention to rare diseases. Regulators have emphasized the need for clinical research in this area to be patient-centered.
S. Lanar +4 more
semanticscholar +1 more source

