Results 61 to 70 of about 1,240,122 (231)

Subconjunctival delivery of p75NTR antagonists reduces the inflammatory, vascular, and neurodegenerative pathologies of diabetic retinopathy [PDF]

, 2017
The p75NTR is a novel therapeutic target validated in a streptozotocin mouse model of diabetic retinopathy. Intravitreal (IVT) injection of small molecule p75NTR antagonist THX-B was therapeutic and resolved the inflammatory, vascular, and ...
Barcelona, Pablo Federico, Galan, Alba, Jian, Yifan, Nedev, Hinyu, Saragovi, H. Uri, Sarunic, Marinko V.   +5 more
core   +1 more source

Qualitative development and content validation of the “SPART” model; a focused ethnography study of observable diagnostic and therapeutic activities in the emergency medical services care process

BMC Emergency Medicine, 2021
Background Clinical reasoning is a crucial task within the Emergency Medical Services (EMS) care process. Both contextual and cognitive factors make the task susceptible to errors.
Bert Dercksen, Michel M. R. F. Struys, Fokie Cnossen, Wolter Paans   +3 more
doaj   +1 more source

To adopt is to adapt: The process of implementing the ICF with an acute stroke multidisciplinary team in England [PDF]

, 2012
Copyright @ 2012 Informa Plc. The article can be accessed from the link below.This article has been made available through the Brunel Open Access Publishing Fund.Purpose: The success of the International Classification of Functioning, Disability and ...
De Souza, LH, Harries, P, Kilbride, C, Tempest, S   +3 more
core   +1 more source

A Roadmap for Investigating Preclinical Autoimmunity Using Patient-Oriented and Epidemiologic Study Designs: Example of Rheumatoid Arthritis

Frontiers in Immunology, 2022
Background & AimsRheumatoid arthritis (RA) is a prototypic autoimmune disease causing inflammatory polyarthritis that affects nearly 1% of the population.
Emily N. Kowalski, Grace Qian, Kathleen M.M. Vanni, Jeffrey A. Sparks, Jeffrey A. Sparks   +4 more
doaj   +1 more source

Assessment of Musculoskeletal Strength and Levels of Fatigue during Different Phases of Menstrual Cycle in Young Adults.

Journal of clinical and diagnostic research : JCDR, 2017
INTRODUCTION Some of the physiological factors and athletic performance might show variation along the phases of menstrual cycle. The alterations seen in these physiological parameters of various systems relating to oscillations in hormonal levels do ...
L. Pallavi, Urban John D. Souza, G. Shivaprakash   +2 more
semanticscholar   +1 more source

Developing a consolidated research framework for clinical allied health professionals practising in the UK

BMC Health Services Research, 2020
Background Allied Health Professionals (AHPs) form a significant part of the healthcare workforce and have great potential to improve services through research and research-informed practice.
J. Harris, K. Grafton, J. Cooke
semanticscholar   +1 more source

The off-label use of drugs for parenteral nutrition as a solvent of substances slightly soluble in water in pharmacological research

Journal of Advanced Pharmaceutical Technology & Research, 2018
Because of the problem to evaluate biological activity in water-soluble substances in all phases of preclinical and clinical studies, the research work enabled to develop the original solvent for poorly soluble compounds based on substances for ...
Aleksandr L Urakov, Ilshat G Mustafin, Aleksandr V Samorodov, Felix Kh Kamilov, Ferkat A Khaliullin   +4 more
doaj   +1 more source

Systematized Nomenclature of Medicine–Clinical Terminology (SNOMED CT) Clinical Use Cases in the Context of Electronic Health Record Systems: Systematic Literature Review

JMIR Medical Informatics, 2023
BackgroundThe Systematized Medical Nomenclature for Medicine–Clinical Terminology (SNOMED CT) is a clinical terminology system that provides a standardized and scientifically validated way of representing clinical information ...
Riikka Vuokko, Anne Vakkuri, Sari Palojoki   +2 more
doaj   +1 more source

Clinical Association Between Psychotic Symptoms and the Gilbert Syndrome: A Case Report

Neuropsychiatric Investigation
Modern research in psychiatry is increasingly focusing on the possible identification of potentially useful biomarkers for early and differential diagnosis and patient-tailored therapy.
Balaswamy Reddy, Alessandra Nocera, Renato de Filippis, Soumitra Das   +3 more
doaj   +1 more source

Biomarker technology roundup: from discovery to clinical applications, a broad set of tools is required to translate from the lab to the clinic

BioTechniques, 2005
Biomarkers are being utilized throughout the drug discovery and development process to understand fundamental biological processes and relationships.
Olivia Scaros, Richard Fisler
doaj   +1 more source