Results 61 to 70 of about 13,287 (281)
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
IEEE Access, 2019 The wide area situational awareness attempts at the expeditious detection of imminent system abnormalities and alerting system operators to take appropriate measures.
Kunja Bihari Swain +2 more
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Technique for pre-compliance testing of phasor measurement units [PDF]
International Journal of Electrical Power & Energy Systems, 2018 Abstract This paper introduces a technique for ‘pre-compliance’ testing of Phasor Measurement Units (PMUs) against the dynamic requirements of the IEEE C37.118.1-2014 standard, which include dynamic and steady-state test scenarios. The tests described are a necessary, but not complete, requirement for passing the IEEE standard and quickly highlight ...
Brogan, Paul V. +5 more
openaire +2 more sources
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Performance Criterion of Phasor Measurement Units for Distribution System State Estimation
IEEE Access, 2019 A phasor measurement unit (PMU) is a device that can directly measure the phase angles of voltages and currents, with high accuracy, using accurate time signals.
Jonghoek Kim, Hyun-Tae Kim, Sungyun Choi
doaj +1 more source
Fast Sequence Component Analysis for Attack Detection in Synchrophasor Networks [PDF]
, 2015 Modern power systems have begun integrating synchrophasor technologies into part of daily operations. Given the amount of solutions offered and the maturity rate of application development it is not a matter of "if" but a matter of "when" in regards to ...
Barella, Richard +6 more
core +2 more sources
AAA+ protein unfoldases—the Moirai of the proteome
FEBS Letters, EarlyView.AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source