Results 31 to 40 of about 215 (132)

PHAST, PHASTER and PHASTEST: Tools for finding prophage in bacterial genomes [PDF]

Briefings in Bioinformatics, 2017
Abstract PHAST (PHAge Search Tool) and its successor PHASTER (PHAge Search Tool – Enhanced Release) have become two of the most widely used web servers for identifying putative prophages in bacterial genomes. Here we review the main capabilities of these web resources, provide some practical guidance regarding their use and discuss ...
David Arndt, Ana Marcu, Yongjie Liang, David S. Wishart   +3 more
openaire   +2 more sources

Modeling and Assessing the Consequences of Oil Pipeline Leakage Using PHAST Software: A Case Study; Jarahi River in Southwest of Iran [PDF]

Journal of Advances in Environmental Health Research
Background: This study models the consequences of oil pipeline leakage using PHAST software, focusing on a segment crossing the Jarahi River in Southwest Iran. The goal is to understand potential environmental and safety impacts, establish safe zones for
Somayeh Zallaghi, Katayoon Varshosaz
doaj   +1 more source

Simulation of pressure tank leakage based on PHAST

IOP Conference Series: Materials Science and Engineering, 2019
Abstract Chemical plants usually store hazardous chemicals in high-pressure or low-pressure storage tanks in the form of pressurization, liquefaction, and low temperature. The poisonous gas in the tank is easily diffused. If a leakage accident occurs, it will cause personal injury and environmental pollution.
Rili Yang, Ke Gai, Fengfeng Yang, Guangsheng Zhang, Ning Sun   +4 more
openaire   +1 more source

Consequence Analysis and Safety Assessment of an Ethylene Oxide Unit in a Petrochemical Complex

International Journal of Environmental Health Engineering
Aim: This study focuses on the consequence analysis and safety assessment of an ethylene oxide (EO) unit in a petrochemical complex. This study evaluates the potential consequences of process accidents in the tankage, tank truck loading, and cylinder ...
Sayed Vahid Esmaeili, Reza Esmaeili, Ali Mohsenian, Ali Alboghobeish   +3 more
doaj   +1 more source

Defining the role of αC helix interactions in the activation of the integrin αI domain

The FEBS Journal, EarlyView.
The α2I domain of the α2β1 integrin contains a distinctive αC helix and a conserved Arg288‐Glu318 ion pair that stabilizes the closed state of the domain. Disruption of this ion pair in the activated α2I variant unwinds the αC helix, which allows interaction with additional collagen‐binding sites increasing collagen binding.
Liisa Pösö, Tomi T. Airenne, Jarmo Käpylä, Hongmin Tu, Eva Bligt‐Lindén, Vimal Parkash, Jyrki Heino, Tiina A. Salminen   +7 more
wiley   +1 more source

Structural Insights Into the Function of Leishmania major Adenylosuccinate Lyase

Proteins: Structure, Function, and Bioinformatics, Volume 94, Issue 10, Page 1686-1701, October 2026.
ABSTRACT One of several intriguing aspects of kinetoplastid biochemistry is the complete dependence on host purines and purine recycling due to the lack of a de novo purine biosynthesis pathway. Adenylosuccinate lyase (ASL, EC 4.3.2.2) is a key enzyme in the purine synthesis pathway responsible for the conversion of adenylosuccinate into adenosine ...
Ivan R. e Silva, Monique Mantovani, Maria E. S. D. Lino, Aline O. Albuquerque, João H. M. da Silva, Ronaldo A. P. Nagem, Adriana L. Rojas, Geraldo R. Sartori, Eduardo Horjales, David Campbell, Otavio H. Thiemann   +10 more
wiley   +1 more source

PHAST: Protein-like heteropolymer analysis by statistical thermodynamics [PDF]

Computer Physics Communications, 2017
PHAST is a software package written in standard Fortran, with MPI and CUDA extensions, able to efficiently perform parallel multicanonical Monte Carlo simulations of single or multiple heteropolymeric chains, as coarse-grained models for proteins. The outcome data can be straightforwardly analyzed within its microcanonical Statistical Thermodynamics ...
openaire   +2 more sources

Unveiling New Insights: Reinterpreting DES Mutation, p.Arg383His, Through a Study of an Iranian Family With Isolated Hypertrophic Cardiomyopathy, Implication for Phenotype–Genotype Correlation Analysis

Clinical Case Reports, Volume 14, Issue 8, August 2026.
ABSTRACT Desmin, a crucial intermediate filament in muscle cells, maintains structural integrity in cardiac muscle and provides stability to striated muscle cells. Mutations in the DES gene lead to desminopathies, causing diverse cardiac and skeletal myopathies.
Saeideh Kavousi, Farzad Kamali, Bahareh Rabbani, Mehrdad Behmanesh, Nejat Mahdieh, Mehrdad Noruzinia   +5 more
wiley   +1 more source

The Clinical Phenotype and Genetic Analysis of Monogenic Non Syndromic Obesity Caused by MC4R Gene Variation

Molecular Genetics &Genomic Medicine, Volume 14, Issue 8, August 2026.
A novel MC4R mutation (c.185A > G) was identified in a 10‐year‐old girl with severe obesity and hyperinsulinemia. Retrospective analysis of 64 pediatric cases revealed that mutation location influences BMI, modulated by underlying disease status, demonstrating that the genotype–phenotype relationship in MC4R‐associated obesity is clinically context ...
Xin Li, Xiaotian Wang, Xin Liu, Shuping Wang, Wentao Yang   +4 more
wiley   +1 more source

Earthquake and Tsunami NaTech Risk Assessment for Oil Storage Facilities

Earthquake Engineering &Structural Dynamics, Volume 55, Issue 9, Page 1887-1904, 25 July 2026.
ABSTRACT Interaction of natural and technological hazards (NaTech) events, such as tsunamis and earthquakes, can affect industrial facilities such as those featuring anchored atmospheric storage tanks. Consequences of natural events on this kind of installation may include the release of hazardous substances, which in turn can lead to industrial ...
Georgios Baltzopoulos, Pasquale Cito, Federica Ricci, Manuela Volpe, Jacopo Selva, Valerio Cozzani, Iunio Iervolino   +6 more
wiley   +1 more source