Results 51 to 60 of about 9,268 (216)

Locating and Activating Molecular 'Time Bombs': Induction of Mycolata Prophages. [PDF]

PLoS ONE, 2016
Little is known about the prevalence, functionality and ecological roles of temperate phages for members of the mycolic acid producing bacteria, the Mycolata.
Zoe A Dyson, Teagan L Brown, Ben Farrar, Stephen R Doyle, Joseph Tucci, Robert J Seviour, Steve Petrovski   +6 more
doaj   +1 more source

Characterisation of the Historic Demographic Decline of the British European Polecat Population

Molecular Ecology, Volume 34, Issue 20, October 2025.
ABSTRACT The European polecat (Mustela putorius) has a widespread distribution across many countries of mainland Europe but is documented to be declining within these ranges. In Britain, direct persecution led to a severe decline of the polecat population during the 19th century. Unlike European mainland populations, it is now recovering across much of
R. Shaw, J. MacPherson, A. C. Kitchener, G. J. Etherington, W. Haerty   +4 more
wiley   +1 more source

Assessment of safe distance for five toxic materials commonly in the accidents of chemical road transportation using ALOHA and PHAST software and CEI index (Case Study: Tehran-Qazvin Highway)

Salāmat-i kār-i Īrān, 2017
Background and aims: Road transportation of chemicals due to occurring various accidents and their hazardous consequences has high importance. The aim of this study was to determine safe distance in the accidents of road transportation of toxic chemicals
Faride Atabi, Roghayeh Ghorbani, Mousa Jabbari   +2 more
doaj  

De Novo HNRNPU Pathogenic Variant Related to Developmental Epileptic Encephalopathy With Inherited KANSL1 Loss‐of‐Function Variant Resolved by RNA Analysis

Molecular Genetics &Genomic Medicine, Volume 13, Issue 9, September 2025.
This study describes a girl with DEE, in whom WGS identified candidate variants in HNRNPU, NIPBL, and KANSL1, with only the de novo HNRNPU variant being causative, while the inherited KANSL1 variant, located in a non‐functional duplicated locus, did not contribute to the phenotype.
Daria Akimova, Daria Guseva, Maria Nefedova, Mikhail Skoblov   +3 more
wiley   +1 more source

Complex Formation between NheB and NheC Is Necessary to Induce Cytotoxic Activity by the Three-Component Bacillus cereus Nhe Enterotoxin. [PDF]

, 2013
The nonhemolytic enterotoxin (Nhe) is known as a major pathogenicity factor for the diarrheal type of food poisoning caused by Bacillus cereus. The Nhe complex consists of NheA, NheB and NheC, all of them required to reach maximum cytotoxicity following ...
Didier, Andrea, Dietrich, Richard, Granum, Per Einar, Heilkenbrinker, Uta, Lindbäck, Toril, Märtlbauer, Erwin, Zhu, Kui   +6 more
core   +3 more sources

A phosphoserine phosphatase variant present in the brain of Alzheimer's disease patients favors nuclear mistargeting

The FEBS Journal, Volume 292, Issue 18, Page 4955-4974, September 2025.
l‐serine levels in the human brain are maintained by the phosphorylated pathway, a three‐step process catalyzed by phosphoglycerate dehydrogenase (PHGDH), phosphoserine aminotransferase (PSAT) and phosphoserine phosphatase (PSP). These enzymes assemble in a metabolon called the serinosome. The double R27S/D32G PSP variant was identified in the brain of
Silvia Sacchi, Valeria Buoli Comani, Ivan Arisi, Francesco Marchesani, Valentina Rabattoni, Omar De Bei, Zoraide Motta, Alessio Peracchi, Stefano Bruno, Loredano Pollegioni, Barbara Campanini   +10 more
wiley   +1 more source

Unveiling a Novel Mechanism of Enhanced Secretion, Cargo Loading, and Accelerated Dynamics of Bacterial Extracellular Vesicles Following Antibiotic Exposure

Journal of Extracellular Vesicles, Volume 14, Issue 7, July 2025.
ABSTRACT Antibiotic exposure substantially alters the production mechanisms of bacterial extracellular vesicles (BEVs), which serve as carriers for intercellular exchange of DNA, proteins, and nutrients, yet the underlying mechanisms remain elusive.
Jinpeng Li, Chao Li, Yun Han, Yulian Hu, Jian Yang, Heting Xu, Xinggui Chen, Ming Yang, Jing Zuo, Yizhi Tang, Changwei Lei, Cui Li, Hongning Wang   +12 more
wiley   +1 more source

Route Planning in Transportation Networks [PDF]

, 2015
We survey recent advances in algorithms for route planning in transportation networks. For road networks, we show that one can compute driving directions in milliseconds or less even at continental scale.
Bast, Hannah, Delling, Daniel, Goldberg, Andrew, Müller-Hannemann, Matthias, Pajor, Thomas, Sanders, Peter, Wagner, Dorothea, Werneck, Renato F.   +7 more
core  

Biomimetic hydroxyapatite nanocrystals are an active carrier for Salmonella bacteriophages [PDF]

, 2019
open access articlePurpose: The use of bacteriophages represents a valid alternative to conventional antimicrobial treatments, overcoming the widespread bacterial antibiotic resistance phenomenon.
Capparelli, Rosanna, Capuano, Federico, Contaldi, Felice, Della Ventura, Bartolomeo, Fulgione, Andrea, Giannini, Cinzia, Ianniello, Flora, Lelli, Marco, Papaianni, Marina, Pastore, Stella, Roveri, Norberto, Sgamma, Tiziana, Velotta, Raffaele   +12 more
core   +2 more sources

Ecological Niche Adaptations Influence Transposable Element Dynamics in Pollinating and Non‐Pollinating Fig Wasps

Ecology and Evolution, Volume 15, Issue 6, June 2025.
The influence of ecological niches on transposable element (TE) dynamics, particularly in mutualistic relationships, remains understudied. This research reveals that non‐pollinating fig wasps (NPFWs) have “aggressive,” expansion‐driven TE landscapes with active insertions, contrasting with the stable, “dormant” TE profiles in pollinators.
Jing Liu, Yun‐Heng Miao, Hong‐Xia Hou, Da‐Wei Huang, Jin‐Hua Xiao   +4 more
wiley   +1 more source