Results 1 to 10 of about 23,681 (206)

The Double-Edge Sword of Natural Phenanthrenes in the Landscape of Tumorigenesis [PDF]

Molecules
Phenanthrenes, which are polycyclic aromatic hydrocarbons comprising three benzene rings, exhibit a diverse range of functions. These compounds are utilized in the synthesis of resins, plant growth hormones, reducing dyes, tannins and other products ...
Yan Liu, Ziwei Du, Chen Sheng, Guangshuai Zhang, Si Yan, Zhijun Zhang, Shuanglin Qin   +6 more
doaj   +3 more sources

Biological evaluation, molecular modeling and dynamics simulation of phenanthrenes isolated from Bletilla striata as butyrylcholinesterase inhibitors

Scientific Reports, 2022
As part of our continuous studies on natural cholinesterase inhibitors from plant kingdom, the 95% ethanol extract from tubers of Bletilla striata showed promising butyrylcholinesterase (BChE) inhibition (IC50 = 8.6 μg/mL).
Yi Liu, Yanbei Tu, Yunyao Kang, Chao Zhu, Chuanhai Wu, Gang Chen, Zerong Liu, Yanfang Li   +7 more
doaj   +2 more sources

Developmental toxicity of alkylated PAHs and substituted phenanthrenes: Structural nuances drive diverse toxicity and AHR activation. [PDF]

Chemosphere
Polycyclic aromatic hydrocarbons (PAHs) are a diverse class of chemicals that occur in complex mixtures including parent and substituted PAHs. To understand the hazard posed by complex environmental PAH mixtures, we must first understand the structural ...
Morshead ML, Truong L, Simonich MT, Moran JE, Anderson KA, Tanguay RL.   +5 more
europepmc   +2 more sources

Juncaceae Species as Promising Sources of Phenanthrenes: Antiproliferative Compounds from Juncus maritimus Lam

Molecules, 2021
Juncaceae family represents an abundant source of phenanthrenes. In continuation of our work aiming at the isolation of biologically active compounds from Juncaceae species, Juncus maritimus Lam.
Norbert Kúsz, Dóra Stefkó, Anita Barta, Annamária Kincses, Nikoletta Szemerédi, Gabriella Spengler, Judit Hohmann, Andrea Vasas   +7 more
doaj   +2 more sources

Photocatalyzed syntheses of phenanthrenes and their aza-analogues. A review

Beilstein Journal of Organic Chemistry, 2020
Phenanthrenes and their aza-analogues have important applications in materials science and in medicine. Aim of this review is to collect recent reports describing their synthesis, which make use of radical cyclizations promoted by a visible light ...
Alessandra Del Tito, Havall Othman Abdulla, Davide Ravelli, Stefano Protti, Maurizio Fagnoni   +4 more
doaj   +2 more sources

Quantitative Analysis of Bioactive Phenanthrenes in Dioscorea batatas Decne Peel, a Discarded Biomass from Postharvest Processing

Antioxidants, 2019
Dioscorea batatas Decne (Chinese yam) has been widely cultivated in East Asia for the purposes of food and medicinal uses for centuries. Along with its high nutritional value, the medicinal value of D.
Minyoul Kim, Myeong Ju Gu, Joon-Goo Lee, Jungwook Chin, Jong-Sup Bae, Dongyup Hahn   +5 more
doaj   +2 more sources

Antiproliferative Phenanthrenes from Juncus tenuis: Isolation and Diversity-Oriented Semisynthetic Modification

Molecules, 2020
The occurrence of phenanthrenes is limited in nature, with such compounds identified only in some plant families. Phenanthrenes were described to have a wide range of pharmacological activities, and numerous research programs have targeted semisynthetic ...
Csaba Bús, Norbert Kúsz, Annamária Kincses, Nikoletta Szemerédi, Gabriella Spengler, László Bakacsy, Dragica Purger, Róbert Berkecz, Judit Hohmann, Attila Hunyadi, Andrea Vasas   +10 more
doaj   +2 more sources

Reactivity of Vinyl Epoxides/Oxetanes/Cyclopropanes toward Arynes: Access to Functionalized Phenanthrenes

ACS Omega, 2021
The reactivity of vinyl epoxides/oxetanes/cyclopropanes toward arynes has been demonstrated under mild conditions to give the corresponding phenanthrenes in moderate to good yields.
Jiupeng Liu, Shuo Tang, Mengyao Zhao, Jianing Huai, Jingya Yu, Jingjing Zhao, Pan Li   +6 more
doaj   +2 more sources

Antiviral activity of phenanthrenes from the medicinal plant Bletilla striata against influenza A virus

BMC Complementary and Alternative Medicine, 2017
Background Influenza represents a serious public health concern. The emergence of resistance to anti-influenza drugs underlines the need to develop new drugs.
Ya Shi, Bing Zhang, Yiyu Lu, Chaodong Qian, Yan Feng, Liwei Fang, Zhishan Ding, Dongqing Cheng   +7 more
doaj   +2 more sources

Phenanthrenes from Juncus Compressus Jacq. with Promising Antiproliferative and Anti-HSV-2 Activities

Molecules, 2018
Juncaceae species are rich sources of phenanthrenes. The present study has focused on the isolation and structure determination of biologically active components from Juncus compressus.
Csaba Bús, Norbert Kúsz, Gusztáv Jakab, Seyyed Ashkan Senobar Tahaei, István Zupkó, Valéria Endrész, Anita Bogdanov, Katalin Burián, Boglárka Csupor-Löffler, Judit Hohmann, Andrea Vasas   +10 more
doaj   +2 more sources