Results 161 to 170 of about 4,409 (215)

Phenanthridine alkaloids from Zanthoxylum madagascariense

Fìtoterapìâ, 2005
Four benzo[c]phenanthridine alkaloids have been isolated from the stem bark of Zanthoxylum madagascariense. These compounds were identified by extensive use of NMR spectroscopy.
M T, Martin, L H, Rasoanaivo, A, Raharisololalao   +2 more
exaly   +3 more sources

Antimalarial benzo[c]phenanthridines

Bioorganic & Medicinal Chemistry Letters, 2005
Analogues of the antimalarial alkaloid nitidine have been prepared with high potency against both chloroquine-sensitive and -resistant strains of Plasmodium falciparum in vitro. Simple modifications, using an established synthetic route, resulted in an analogue with IC(50) below 5ng/mL against a chloroquine-sensitive strain of P. falciparum.
James M, Nyangulu, Samantha L, Hargreaves, Susan L, Sharples, Simon P, Mackay, Roger D, Waigh, Olivier, Duval, Eddie K, Mberu, William M, Watkins   +7 more
openaire   +2 more sources

Phenanthridines

ChemInform, 2005
AbstractFor Abstract see ChemInform Abstract in Full Text.
openaire   +1 more source

Redetermination of the structure of phenanthridine

Acta Crystallographica Section C Crystal Structure Communications, 1993
C 13 H 9 N, M r =179.22, orthorhombic, P2 1 2 1 2 1 , a=4.872 (2), b=11.526 (4), c= 15.811 (4) A, V=887.7 (5) A 3 , Z=4, D x = 1.341 Mg m -3 , λ(Mo Kα)=0.71069 A, μ= 0.07 mm -1 , F(000)=376, T=110 K, final R=0.045 for 1713 observed reflections. Phenanthridine was found to be planar in the solid state with a mean deviation of 0.002 A from the mean plane
Brett, W.a., Rademacher, Paul, Boese, Roland   +2 more
openaire   +1 more source

Acridities and phenanthridines

2020
The acridine and phenanthridine chromophores both contain a central six-membered aromatic nitrogen heterocycle, with benzo rings fused onto each side. Although sulfonated and hydroxylated acridines have been synthesized, none are used as stains. The hydrophilic/lipophilic properties of the dyes under usage conditions are varied.
openaire   +1 more source

Spiropyrans of the phenanthridine series

Chemistry of Heterocyclic Compounds, 1974
The relative stabilities of the cyclic and open forms of spiropyrans of the phenanthridine series depend on the character and position of the substituents in the chromene ring and also on the polarity of the media. The structure of the open forms of the spiropyrans is closer to the limiting dipolar structure.
�. R. Zakhs, V. P. Martynova, L. S. �fros   +2 more
openaire   +1 more source

Thiophene Analogus of Phenanthridine

Synthetic Communications, 1972
Abstract We reported reoently1 that the dithienpyridones I-III could be prepared by the cyclisation of the appropriate dithienylazides.
G. J. Heeres, Hans Wynkrg
openaire   +1 more source

Synthesis of Phenanthridine Derivatives via Photolysis

The Journal of Organic Chemistry, 2011
An improved photochemical method for producing the prolifically bioactive phenanthridine system is reported. A wide variety of derivatives were obtained in two steps in yields ranging from 31 to 95%.
Linsenmeier, A., Bräse, S., Williams, C. M.   +2 more
openaire   +4 more sources

Synthesis and characterization of oxadisilole-fused phenanthridines and dioxatrisilole-fused phenanthridines from benzyne

Tetrahedron, 2015
Abstract An efficient protocol for the synthesis of oxadisilole-fused phenanthridines and dioxatrisilole-fused phenanthridines by aza Diels–Alder reactions and dehydrogenation aromatization reactions of benzyne with N-benzylideneanilines in good yields at room temperature.
Jingda Chen, Yali Chen, Xueli Wang, Kundi Kong, Weiguo Cao, Jie Chen   +5 more
openaire   +1 more source

Synthesis of Pyrrolo[a]- and Pyrrolo[c]phenanthridine Derivatives and Indolinyl and Indolylsubstituted 6-Phenanthridines

Chemistry of Heterocyclic Compounds, 2001
The corresponding Mannich bases have been synthesized by the aminomethylation of 6-methyl-1H-pyrrolo[2,3-a]- and 4-methyl-3H-pyrrolo[3,2-c]phenanthridinium iodides. The interaction of 6-chloro-phenanthridine with indoline and with 5-amino-N-acetylindoline gave the corresponding derivatives of phenanthridine.
E. P. Baberkina, V. N. Buyanov, M. E. Zhukova, A. E. Shchekotikhin, V. E. Zhigachev, N. N. Suvorov   +5 more
openaire   +1 more source