Frontiers in Veterinary Science, 2021 Background:Macleaya cordata (Willd.) (Papaveraceae) is listed as a feed additive in animal production by the European Food Authority.Methods: The metabolites of chelerythrine in rats were measured in vitro and in vivo by rapid and accurate high ...
Zhao-Ying Liu
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Antibacterial Effect and Mechanism of Chelerythrine on Xanthomonas oryzae pv. oryzae [PDF]
MicroorganismsXanthomonas oryzae pv. oryzae (Xoo) is a biotrophic bacterial pathogen, which causes devastating bacterial blight disease worldwide. In this study, we thoroughly investigated the antimicrobial effect of the plant-derived extract chelerythrine against ...
Yi Yan +4 more
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Chelerythrine-Mediated Growth Inhibition and Resistance Mechanism in Bacillus tropicus [PDF]
MicroorganismsChelerythrine (CHE) is a naturally occurring benzophenanthridine alkaloid obtained from plants such as Chelidonium majus L. It has received notable attention in pharmacology and microbial control because of its broad-spectrum activity and marked anti ...
Jueyu Wang +4 more
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Biotechnological Advances in Sanguinarine and Chelerythrine Production from Plume Poppy (Macleaya cordata): A Gene Editing Perspective [PDF]
PlantsPlume poppy (Macleaya cordata), an important member of the Papaveraceae family, is a substantial source of benzylisoquinoline alkaloids (BIAs) such as sanguinarine and chelerythrine.
Bilal A. Rather +8 more
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Metabolic engineering of Saccharomyces cerevisiae for chelerythrine biosynthesis [PDF]
Microbial Cell FactoriesBackground Chelerythrine is an important alkaloid used in agriculture and medicine. However, its structural complexity and low abundance in nature hampers either bulk chemical synthesis or extraction from plants.
Jiawei Zhu +7 more
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Evaluating Chelerythrine Chloride as a Potential Treatment for Multidrug-Resistant Gonorrhea [PDF]
Infection and Drug ResistanceRan Zhang,1,2,* Yuqiu Qi,2,* Hui Peng,2,* Chenlong Tao,2,3 Songwei Lu,2 Qiankun Ke,2 Shangzhu Shen,2 Zhuo Wang,1,2 Xiaomian Lin1,2,4 1Department of Pharmacy, Anhui University of Chinese Medicine, Hefei, 230012, People’s Republic ...
Zhang R +8 more
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Chelerythrine Inhibits TGF-β-Induced Epithelial–Mesenchymal Transition in A549 Cells via RRM2 [PDF]
PharmaceuticalsBackground: The mechanisms underlying the metastasis of non-small-cell lung cancer (NSCLC) have long been a focal point of medical research. The anti-tumor effects of chelerythrine (CHE) have been confirmed; however, its ability to inhibit tumor ...
Jinlong Liu +7 more
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Sanguinarine–Chelerythrine from Coptis chinensis Offers Analgesic and Anti-Inflammatory Effects Without Gastrotoxicity [PDF]
PharmaceuticsBackground: Pain is a major clinical and socioeconomic problem worldwide. The available therapies are not always effective and are often associated with the multiple adverse effects that reduce their clinical application.
Maciej Danielewski +9 more
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Chelerythrine Protects Against Acetaminophen-Induced Acute Liver Injury: Insights from Gut Microbiota and Multi-Omics Analysis [PDF]
AntioxidantsChelerythrine (CHE) is the main active component of Chelidonium majus L., possessing excellent antioxidant and anti-inflammatory properties. However, the protective effects of CHE against liver injury and its underlying mechanisms remain unclear.
Jinlong Liu +8 more
doaj +2 more sources
Molecules, 2012 In order to understand the antifungal activity of some derivatives of sanguinarine (S) and chelerythrine (C) and their structure-activity relationships, sixteen derivatives of S and C were prepared and evaluated for in vitro antifungal activity against ...
Le Zhou
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