Results 41 to 50 of about 3,120 (165)

Metabolomics Analysis of the Effects of Chelerythrine on Ustilaginoidea virens [PDF]

, 2022
Abstract Background: Rice false smut (RFS), caused by Ustilaginoidea virens, is widely distributed in major rice-producing regions. Previous studies showed that treating RFS with chelerythrine can decrease fungus spore germination by 86.7% and induce fungal cell apoptosis.
Qinghui Wei, Weifeng Song, Zhiyong Li, Yaqing Pan, Xihai Zhai, Baoying Li, Zhanli Jiao   +6 more
openaire   +1 more source

Traditional Chinese Medicine for lung cancer: Mechanisms, clinical evidence, and future perspectives

Precision Medical Sciences, Volume 15, Issue 3, Page 206-226, September 2026.
Graphical abstract represents the risk factors for lung cancer, TCM efficacy and clinical outcomes to future challenges. Abstract Lung cancer remains a leading cause of global cancer mortality. Despite advances in conventional treatments such as surgery, chemotherapy, targeted therapy, and immunotherapy, challenges including drug resistance, toxicity ...
Zhangdeng Chen, Liujun Bao
wiley   +1 more source

Stage‐Specific H3K14 and H3K23 Succinylation Orchestrates Insect Metamorphosis and Oogenesis

Advanced Science, Volume 13, Issue 43, 3 August 2026.
Stage‐specific succinylation of histone H3 at lysine 14 and 23 differentially controls insect metamorphosis and oogenesis through distinct GPCR‐PKC signaling cascades, revealing an evolutionarily conserved epigenetic mechanism that coordinates key life‐history traits.
Yu‐Pu Jing, Lunjie Li, Libin Yang, Lin‐Jie Zhang, Qiang Yan, Ci Zhang, Zanrong Wen, Guangze Yu, Qian Li, Shutang Zhou   +9 more
wiley   +1 more source

Structure-activity relationship of benzophenanthridine alkaloids from Zanthoxylum rhoifolium having antimicrobial activity.

PLoS ONE, 2014
Zanthoxylum rhoifolium (Rutaceae) is a plant alkaloid that grows in South America and has been used in Brazilian traditional medicine for the treatment of different health problems. The present study was designed to evaluate the antimicrobial activity of
Luciana de C Tavares, Graciane Zanon, Andréia D Weber, Alexandre T Neto, Clarice P Mostardeiro, Ivana B M Da Cruz, Raul M Oliveira, Vinicius Ilha, Ionara I Dalcol, Ademir F Morel   +9 more
doaj   +1 more source

Autolysin N617 Deamidation as a Molecular Target of Chelerythrine in Methicillin-Resistant

Natural Product Communications
Objective Methicillin-resistant Staphylococcus aureus (MRSA) is a major clinical challenge due to its resistance to multiple antibiotics. Chelerythrine, a natural benzophenanthridine alkaloid, shows antibacterial activity against MRSA, but its precise ...
Jianhua Liao, Chunyan Meng, Baoqing Liu, Yuechun Wang, Jun Cheng   +4 more
doaj   +1 more source

Plant‐Derived Treatments for Monogenean Parasites in Farmed Fish: A Systematic Review and Meta‐Analysis

Reviews in Aquaculture, Volume 18, Issue 3, June 2026.
ABSTRACT Monogeneans are among the most problematic ectoparasites in finfish aquaculture. Plant‐derived compounds have been widely explored as therapeutic agents, yet their efficacy and safety have not been quantitatively synthesized across studies. This study provides a meta‐analysis of plant‐based treatments against monogeneans, integrating 453 in ...
Francisco Neptalí Morales‐Serna
wiley   +1 more source

Single‐cell analysis reveals neuroprotective histone deacetylase inhibitor pathways

Alzheimer's &Dementia, Volume 22, Issue 2, February 2026.
Abstract INTRODUCTION Alzheimer's disease (AD) involves β‐amyloid (Aβ) accumulation, tau pathology, and neuroinflammation, driving cognitive decline. Despite extensive research, disease‐modifying therapies remain elusive. We integrated single‐cell RNA sequencing (scRNA‐seq), spatial transcriptomics, and in vitro validation to identify repurposable ...
Madeline Peyton, Nur Jury‐Garfe, Jiahui Liu, Caleb Beimfohr, Chitra Sunil, Steven Brooks, Pengyue Zhang, Sean D. McCabe, Timothy I. Richardson, Kun Huang, Cristian A. Lasagna‐Reeves, Jie Zhang, Travis S. Johnson   +12 more
wiley   +1 more source

Recent Advances in Metal‐Organic Framework‐Integrated Nanocomposite Hydrogels for Sensors and Sensing Systems

SmartMat, Volume 7, Issue 1, February 2026.
Metal‐organic framework–hydrogel composites are explored as multifunctional materials for next‐generation sensors and sensing systems. This review summarizes recent advances in employing these smart composites to fabricate optical, electrochemical, and electromechanical sensors, emphasizing their potential in healthcare, biomedical diagnostics ...
Md Sazzadur Rahman, Emna Helal, Nicole R. Demarquette   +2 more
wiley   +1 more source

Screening Papaveraceae as Novel Antibiofilm Natural-Based Agents

Molecules, 2021
The antimicrobial properties of herbs from Papaveraceae have been used in medicine for centuries. Nevertheless, mutual relationships between the individual bioactive substances contained in these plants remain poorly elucidated.
Sylwia Zielińska, Magdalena Dziągwa-Becker, Adam Junka, Ewelina Piątczak, Anna Jezierska-Domaradzka, Malwina Brożyna, Justyna Paleczny, Aleksandra Sobiecka, Wojciech Słupski, Eleonora Mess, Mariusz Kucharski, Serhat Sezai Çiçek, Christian Zidorn, Adam Matkowski   +13 more
doaj   +1 more source

Effects of an Isoquinoline Alkaloids Blend on the Expression of Genes Relevant for Antioxidant Capacity, Barrier Integrity and Inflammation Along the Broiler Gut

Journal of Animal Physiology and Animal Nutrition, Volume 110, Issue 1, Page 1-12, January 2026.
ABSTRACT Intensive broiler production may lead to perturbations of gut function and health. The maintenance of intestinal homeostasis in broilers through the use of dietary phytogenic components such as isoquinoline alkaloids (IQs) is an emerging topic of scientific investigations.
Vasileios V. Paraskeuas, Ioannis Brouklogiannis, Anja Pastor, Konstantinos C. Mountzouris   +3 more
wiley   +1 more source