Results 61 to 70 of about 9,197 (244)

Hormone-stimulated modulation of endocytic trafficking in osteoclasts [PDF]

, 2012
Copyright @ 2012 Stenbeck, Lawrence and Albert. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in other forums, provided the original authors and ...
Albert, AP, Lawrence, KM, Stenbeck, G
core   +2 more sources

Plant‐Derived Treatments for Monogenean Parasites in Farmed Fish: A Systematic Review and Meta‐Analysis

Reviews in Aquaculture, Volume 18, Issue 3, June 2026.
ABSTRACT Monogeneans are among the most problematic ectoparasites in finfish aquaculture. Plant‐derived compounds have been widely explored as therapeutic agents, yet their efficacy and safety have not been quantitatively synthesized across studies. This study provides a meta‐analysis of plant‐based treatments against monogeneans, integrating 453 in ...
Francisco Neptalí Morales‐Serna
wiley   +1 more source

Autolysin N617 Deamidation as a Molecular Target of Chelerythrine in Methicillin-Resistant

Natural Product Communications
Objective Methicillin-resistant Staphylococcus aureus (MRSA) is a major clinical challenge due to its resistance to multiple antibiotics. Chelerythrine, a natural benzophenanthridine alkaloid, shows antibacterial activity against MRSA, but its precise ...
Jianhua Liao, Chunyan Meng, Baoqing Liu, Yuechun Wang, Jun Cheng   +4 more
doaj   +1 more source

Screening Papaveraceae as Novel Antibiofilm Natural-Based Agents

Molecules, 2021
The antimicrobial properties of herbs from Papaveraceae have been used in medicine for centuries. Nevertheless, mutual relationships between the individual bioactive substances contained in these plants remain poorly elucidated.
Sylwia Zielińska, Magdalena Dziągwa-Becker, Adam Junka, Ewelina Piątczak, Anna Jezierska-Domaradzka, Malwina Brożyna, Justyna Paleczny, Aleksandra Sobiecka, Wojciech Słupski, Eleonora Mess, Mariusz Kucharski, Serhat Sezai Çiçek, Christian Zidorn, Adam Matkowski   +13 more
doaj   +1 more source

Sevoflurane enhances ethanol-induced cardiac preconditioning through modulation of protein kinase C, mitochondrial KATP channels, and nitric oxide synthase, in guinea pig hearts. [PDF]

, 2008
BACKGROUND: Volatile anesthetics and regular ethanol consumption induce cardioprotection mimicking ischemic preconditioning. We investigated whether sevoflurane enhances ethanol preconditioning and whether inhibition of protein kinase C (PKC) and ...
Domae, Naochika, Figueredo, Vincent M, Inamura, Yoshitaka, Kaneda, Kazuhiro, Kotani, Junichiro, Miyamae, Masami, Okusa, Chika, Sugioka, Shingo   +7 more
core   +2 more sources

Single‐cell analysis reveals neuroprotective histone deacetylase inhibitor pathways

Alzheimer's &Dementia, Volume 22, Issue 2, February 2026.
Abstract INTRODUCTION Alzheimer's disease (AD) involves β‐amyloid (Aβ) accumulation, tau pathology, and neuroinflammation, driving cognitive decline. Despite extensive research, disease‐modifying therapies remain elusive. We integrated single‐cell RNA sequencing (scRNA‐seq), spatial transcriptomics, and in vitro validation to identify repurposable ...
Madeline Peyton, Nur Jury‐Garfe, Jiahui Liu, Caleb Beimfohr, Chitra Sunil, Steven Brooks, Pengyue Zhang, Sean D. McCabe, Timothy I. Richardson, Kun Huang, Cristian A. Lasagna‐Reeves, Jie Zhang, Travis S. Johnson   +12 more
wiley   +1 more source

17β-estradiol abrogates apoptosis inhibiting PKCδ, JNK and p66Shc activation in C2C12 cells [PDF]

, 2015
17β-Estradiol (E2) protects several non-reproductive tissues from apoptosis, including skeletal muscle. Previously, we showed that E2 at physiological concentrations prevented apoptosis induced by H2O2 in skeletal myoblasts.
Ahnadi, Almeida, Armstrong, Assert, Blass, Bokoch, Boland, Bradford, Brodie, Burattini, Chambers, Chen, Chen, Corbalan-Garcia, Dionne, Gutcher, Hibi, Jackson, Jejurikar, Jejurikar, Jiang, Kikkawa, Konishi, La Colla, Laemmli, Livak, Migliaccio, Migliaccio, Milanesi, Newton, Nishizuka, Pelicci, Pellegrini, Pronsato, Razandi, Reyland, Rodriguez-Pena, Ronda, Shanmugam, Spyridopoulos, Steinberg, Takuwa, Tukey, Vasconsuelo, Vasconsuelo, Ventura, Wang, Yao, Yoshida, Yoshida   +49 more
core   +1 more source

Recent Advances in Metal‐Organic Framework‐Integrated Nanocomposite Hydrogels for Sensors and Sensing Systems

SmartMat, Volume 7, Issue 1, February 2026.
Metal‐organic framework–hydrogel composites are explored as multifunctional materials for next‐generation sensors and sensing systems. This review summarizes recent advances in employing these smart composites to fabricate optical, electrochemical, and electromechanical sensors, emphasizing their potential in healthcare, biomedical diagnostics ...
Md Sazzadur Rahman, Emna Helal, Nicole R. Demarquette   +2 more
wiley   +1 more source

Involvement of Protein Kinase C and Protein Kinase A in the Enhancement of L-type Calcium Current by GABA\u3csub\u3eB\u3c/sub\u3e Receptor Activation in Neonatal Hippocampus [PDF]

, 2011
In the early neonatal period activation of GABAB receptors attenuates calcium current through N-type calcium channels while enhancing current through L-type calcium channels in rat hippocampal neurons.
Bray, Jennifer Grace, Mynlieff, Michelle
core   +1 more source

Nuclear Dbf2-related protein kinases (NDRs) in isolated cardiac myocytes and the myocardium: activation by cellular stresses and by phosphoprotein serine-/threonine-phosphatase inhibitors [PDF]

, 2008
The nuclear Dbf2-related protein kinases 1 and 2 (NDR1/2) are closely-related AGC family kinases that are strongly conserved through evolution. In mammals, they are activated inter alia by phosphorylation of an hydrophobic domain threonine-residue [NDR1 ...
Clerk, Angela, Cornils, H, Cullingford, Timothy E., Fuller, Stephen John, Hemmings, B. A., Hergovitch, A, Molkentin, Jeff D., Pikkarainen, Sampsa, Sugden, Peter H., Tham, El Li   +9 more
core   +1 more source