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Toxicological Effects of Berberine and Sanguinarine [PDF]
Frontiers in Molecular Biosciences, 2018 Berberine and Sanguinarine alkaloids belong to a group of naturally occurring chemical compounds that mostly contain basic nitrogen atoms. This group also includes some related compounds with neutral or weakly acidic properties. Alkaloids are produced by
Nitika Singh, Bechan Sharma
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Dihydrosanguinarine enhances tryptophan metabolism and intestinal immune function via AhR pathway activation in broilers [PDF]
Journal of Animal Science and BiotechnologyBackground Tryptophan is essential for nutrition, immunity and neural activity, but cannot be synthesized endogenously. Certain natural products influence host health by modulating the gut microbiota to promote the production of tryptophan metabolites ...
Yue Su +4 more
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Intein-mediated temperature control for complete biosynthesis of sanguinarine and its halogenated derivatives in yeast [PDF]
Nature CommunicationsWhile sanguinarine has gained recognition for antimicrobial and antineoplastic activities, its complex conjugated structure and low abundance in plants impede broad applications.
Yuanwei Gou +17 more
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Synthesis and fungicidal activities of sanguinarine derivatives
Pesticide Biochemistry and Physiology, 2018 • Three groups of 32 sanguinarine analogues were synthesized via facile methods and characterized.
Pei Lv, Taozhong Shi, Xiangwei Wu
exaly +4 more sources
Sanguinarine, identified as a natural alkaloid LSD1 inhibitor, suppresses lung cancer cell growth and migration [PDF]
Iranian Journal of Basic Medical Sciences, 2022 Objective(s): Lysine-specific demethylase1 (LSD1), an important class of histone demethylases, plays a crucial role in regulation of mammalian biology. The up-regulated LSD1 expression was frequently associated with progress and oncogenesis of multiple ...
Ting-ting Qin +7 more
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Molecules, 2021 Peroxisome proliferator-activated receptors (PPARs) play crucial roles in glucose and lipid metabolism and inflammation. Sanguinarine is a natural product that is isolated from Sanguinaria Canadensis, a potential therapeutic agent for intervention in ...
Siyu Tian +5 more
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iScience, 2022 Summary: The longevity of an organism is influenced by both genetic and environmental factors. With respect to genetic factors, a significant effort is being made to identify pharmacological agents that extend lifespan by targeting pathways with a ...
Fang Liu +12 more
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Poultry Science, 2022 : Eimeria tenella (E. tenella) is the most pathogenic genus in Eimeria and can lead to a huge number of deaths of chickens, causing significant economic losses in the poultry industry worldwide.
Jun-Yi Li +7 more
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Apoptosis induction of human bladder cancer cells by sanguinarine through reactive oxygen species-mediated up-regulation of early growth response gene-1. [PDF]
PLoS ONE, 2013 Although the effects of sanguinarine, a benzophenanthridine alkaloid, on the inhibition of some kinds of cancer cell growth have been established, the underlying mechanisms are not completely understood.
Min Ho Han +7 more
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Translational Oncology, 2022 Objectives: Small cell lung cancer (SCLC) is notorious for aggressive malignancy without effective treatment, and most patients eventually develop tumor progression with a poor prognosis.
Mingtian Zhong +8 more
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