Results 31 to 40 of about 2,721 (182)

Disruption of nucleocytoplasmic trafficking of cyclin D1 and topoisomerase II by sanguinarine

BMC Cell Biology, 2006
Background The quaternary isoquinoline alkaloid sanguinarine is receiving increasing attention as a potential chemotherapeutic agent in the treatment of cancer.
Perkins Edward, Lamont Genelle, Holy Jon
doaj   +1 more source

Safety and efficacy of a feed additive consisting of Macleaya cordata (Willd.) R. Br. extract and leaves (Sangrovit® extra) for all poultry species (excluding laying and breeding birds) (Phytobiotics Futterzusatzstoffe GmbH)

EFSA Journal, 2023
Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety and efficacy of Macleaya cordata (Willd.) R. Br.
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP), Vasileios Bampidis, Giovanna Azimonti, Maria de Lourdes Bastos, Henrik Christensen, Birgit Dusemund, Mojca Durjava, Maryline Kouba, Marta López‐Alonso, Secundino López Puente, Francesca Marcon, Baltasar Mayo, Alena Pechová, Mariana Petkova, Fernando Ramos, Yolanda Sanz, Roberto Edoardo Villa, Ruud Woutersen, Paul Brantom, Andrew Chesson, Johannes Westendorf, Paola Manini, Jordi Ortuño Casanova, Birgit Dusemund   +23 more
doaj   +1 more source

Sanguinarine Protects Channel Catfish against Aeromonas hydrophila Infection by Inhibiting Aerolysin and Biofilm Formation

Pathogens, 2022
Aeromonas hydrophila is a pathogenic bacterium that can cause serious infections both in humans and aquatic animals. Antibiotics are the main approach for fighting against the pathogen.
Lushan Zhang, Liang Ma, Qiuhong Yang, Yongtao Liu, Xiaohui Ai, Jing Dong   +5 more
doaj   +1 more source

Metabolism and Tissue Distribution of Chelerythrine and Effects of Macleaya Cordata Extracts on Liver NAD(P)H Quinone Oxidoreductase

Frontiers in Veterinary Science, 2021
Background:Macleaya cordata (Willd.) (Papaveraceae) is listed as a feed additive in animal production by the European Food Authority.Methods: The metabolites of chelerythrine in rats were measured in vitro and in vivo by rapid and accurate high ...
Chong-Yin Huang, Chong-Yin Huang, Ya-Jun Huang, Ya-Jun Huang, Zhuo-Yi Zhang, Zhuo-Yi Zhang, Yi-Song Liu, Zhao-Ying Liu, Zhao-Ying Liu   +8 more
doaj   +1 more source

Alkaloid Biosynthesis in the Early Stages of the Germination of Argemone mexicana L. (Papaveraceae)

Plants, 2021
The synthesis of the benzylisoquinoline alkaloids, sanguinarine and berberine, was monitored in Argemone mexicana L. (Papaveracea) throughout the early stages of its hypocotyl and seedling development.
Jorge Xool-Tamayo, Yahaira Tamayo-Ordoñez, Miriam Monforte-González, José Armando Muñoz-Sánchez, Felipe Vázquez-Flota   +4 more
doaj   +1 more source

Photophysical Property of Sanguinarine in the Excited Singlet State [PDF]

Photochemistry and Photobiology, 1992
Abstract—The photophysical property of the alkanolamine form of sanguinarine has been studied in aqueous and organic medium under various environmental conditions from the measurement of absorption, fluorescence and NMR spectroscopy. Alkanolamine fluorescence shows an excitation time dependent fluorescence quenching and the rate of quenching increases ...
A, Das, R, Nandi, M, Maiti
openaire   +2 more sources

Intein-mediated temperature control for complete biosynthesis of sanguinarine and its halogenated derivatives in yeast

Nature Communications
While sanguinarine has gained recognition for antimicrobial and antineoplastic activities, its complex conjugated structure and low abundance in plants impede broad applications.
Yuanwei Gou, Dongfang Li, Minghui Zhao, Mengxin Li, Jiaojiao Zhang, Yilian Zhou, Feng Xiao, Gaofei Liu, Haote Ding, Chenfan Sun, Cuifang Ye, Chang Dong, Jucan Gao, Di Gao, Zehua Bao, Lei Huang, Zhinan Xu, Jiazhang Lian   +17 more
doaj   +1 more source

Molecular Determinants of Sensitivity or Resistance of Cancer Cells Toward Sanguinarine

Frontiers in Pharmacology, 2018
For decades, natural products represented a significant source of diverse and unique bioactive lead compounds in drug discovery field. In Clinical oncology, complete tumors remission is hampered by the development of drug-resistance.
Mohamed E. M. Saeed, Nuha Mahmoud, Yoshikazu Sugimoto, Thomas Efferth, Heba Abdel-Aziz, Heba Abdel-Aziz   +5 more
doaj   +1 more source

Assessing Performance and Safety of Feeding a Standardized Macleaya cordata Extract to Calves

Animals, 2022
This study examined the effects of Sangrovit®, a Macleaya cordata plant extract (MCE) preparation on feed intake, growth, blood chemistry, and tissue-residue levels of calves.
Ray A. Matulka, Janaka Wickramasinghe, Juliane Dohms, Flavio Rodrigues Borges Ribeiro, Ranga Appuhamy   +4 more
doaj   +1 more source

Induction of contracture and extracellular Ca2+ influx in cardiac muscle by sanguinarine: a study on cardiotoxicity of sanguinarine

Journal of Biomedical Science, 2005
In this study, the toxic effect of sanguinarine (SANG) on heart was studied with isolated cardiac muscle strip isolated from Wistar rat. SANG induced positive inotropic action followed by contracture on the left ventricle and both atria strips. In addition, SANG dose-dependently inhibited spontaneous beat of the right atrium.
Chien Ming, Hu, Yu Wen, Cheng, Jiunn Wang, Liao, Huei Wen, Cheng, Jaw Jou, Kang   +4 more
openaire   +2 more sources