Results 51 to 60 of about 3,726 (205)
Discovery of pseudobaptigenin synthase in fungal‐infected Trifolium pratense roots
The Plant Journal, Volume 127, Issue 1, July 2026.Significance Statement The discovery of pseudobaptigenin synthase in red clover (CYP76F319), catalyzing the formation of a methylenedioxy bridge to convert calycosin to pseudobaptigenin. The integration of metabolomic and transcriptomic datasets to describe the defense response in red clover roots to hemibiotrophic and necrotrophic fungi.
Lee Marie Raytek +3 more
wiley +1 more source
LifeThis study evaluated the efficacy of graded dietary sanguinarine as a phytobiotic alternative for mitigating Clostridium perfringens-induced enteric challenge in broiler chickens.
Ali R. Al Sulaiman, Ala E. Abudabos
doaj +1 more source
Journal of Biomedical Science, 2005 In this study, the toxic effect of sanguinarine (SANG) on heart was studied with isolated cardiac muscle strip isolated from Wistar rat. SANG induced positive inotropic action followed by contracture on the left ventricle and both atria strips. In addition, SANG dose-dependently inhibited spontaneous beat of the right atrium.
Chien Ming, Hu +4 more
openaire +2 more sources
Sanguinarine and Its Salts [PDF]
The Boston Medical and Surgical Journaln ...
openaire +1 more source
Rapid human melanoma cell death induced by sanguinarine through oxidative stress [PDF]
, 2013 Sanguinarine is a natural isoquinoline alkaloid derived from the root of Sanguinaria canadensis and from other poppy fumaria species, and is known to have a broad spectrum of pharmacological properties.
Mollinedo, Faustino +4 more
core +1 more source
Vacuolization as a Novel Approach to Cancer Therapy
Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 6, June 2026.This review discusses the novel strategy of inducing vacuole formation in cancer cells using small molecules, that induce nonapoptotic cell death mechanisms, such as paraptosis, oncosis, autophagy, and methuosis, and its potential in overcoming resistance to apoptosis‐based cancer therapies.
Mariah Pasternak +9 more
wiley +1 more source
Toxins, 2019 Isoquinoline alkaloids belong to the toxic secondary metabolites occurring in plants of many families. The high biological activity makes these compounds promising agents for use in medicine, particularly as anticancer drugs.
Anna Och +5 more
doaj +1 more source
Progress in Natural Products Target Discovery Technology
MedComm, Volume 7, Issue 6, June 2026.Here, we provide a comprehensive overview of current technologies and recent advancements in therapeutic target discovery for natural products. By systematically synthesizing the principles, methodologies, and practical applications of existing experimental and computational strategies, this work provides a more actionable reference framework for ...
Qiyuan Pan +7 more
wiley +1 more source
Zhongliu Fangzhi Yanjiu, 2019 Objective To investigate the effect of sanguinarine on the invasion and migration of lung adenocarcinoma cells and its preliminary molecular mechanism. Methods MTT assay was used to observe the proliferative capacity of A549 and H1975 cells.
YANG Jia +4 more
doaj +1 more source
Isoquinoline alkaloids supplementation on performance and carcass traits of feedlot bulls [PDF]
Asian-Australasian Journal of Animal Sciences, 2018 Objective Isoquinoline Alkaloids, derived from one plant (Macleaya cordata) can be an alternative when it is desired to increase performance in feedlot cattle.
Alex Michels +8 more
doaj +1 more source