Results 51 to 60 of about 5,249 (228)

Functional diversity of 2-oxoglutarate/Fe(II)-dependent dioxygenases in plant metabolism [PDF]

, 2014
Oxidative enzymes catalyze many different reactions in plant metabolism. Among this suite of enzymes are the 2-oxoglutarate/Fe(II)-dependent dioxygenases (2-ODDs). Cytochromes P450 (CYPs) as often considered the most versatile oxidative enzymes in nature,
Peter J. Facchini, Scott C. Farrow
core   +2 more sources

Photophysical Property of Sanguinarine in the Excited Singlet State [PDF]

Photochemistry and Photobiology, 1992
Abstract—The photophysical property of the alkanolamine form of sanguinarine has been studied in aqueous and organic medium under various environmental conditions from the measurement of absorption, fluorescence and NMR spectroscopy. Alkanolamine fluorescence shows an excitation time dependent fluorescence quenching and the rate of quenching increases ...
A, Das, R, Nandi, M, Maiti
openaire   +2 more sources

Protection and Delivery of Phytochemicals from Passive Encapsulation to Guaranteed Self‐Assembly Induced by Amyloid Template for Chronic Disease Prevention via Modulating Microbial‐Host Crosstalk

Advanced Science, Volume 13, Issue 21, 13 April 2026.
ABSTRACT The rising incidence of chronic diseases globally has drawn widespread attention to phytochemicals, which exert targeted preventive and alleviating effect by modulating gut microbiota; thus, a potential strategy for precision nutritional interventions is offered.
Shiqi Bai, Siying Cheng, Fengguang Ma, Xiaorong Zhang, Jianan Huang, Zhonghua Liu, Bing Hu   +6 more
wiley   +1 more source

A “reverse pharmacology” approach for developing an anti-malarial phytomedicine [PDF]

, 2011
A "reverse pharmacology" approach to developing an anti-malarial phytomedicine was designed and implemented in Mali, resulting in a new standardized herbal anti-malarial after six years of research.
Bertrand Graz, Chiaka Diakite, Drissa Diallo, Jacques Falquet, Merlin L Willcox, Sergio Giani   +5 more
core   +3 more sources

Reducing the Sinapine Levels of Camelina sativa Seeds Through Targeted Genome Editing of REF1

Plant Biotechnology Journal, Volume 24, Issue 3, Page 1839-1865, March 2026.
ABSTRACT Sinapine (O‐sinapoyl choline) is the major phenolic metabolite typically found in the oil‐rich seeds of Brassicaceae such as Camelina sativa and Brassica napus. It imparts a bitter taste to the seeds as a defence mechanism against herbivores, but it also renders them less palatable to livestock.
Amélie A. Kelly, Martin Fulda, Merle Aden, Ilka N. Abreu, Kirstin Feussner, Ivo Feussner   +5 more
wiley   +1 more source

The induced and intrinsic resistance of Escherichia coli to sanguinarine is mediated by AcrB efflux pump

Microbiology Spectrum
Sanguinarine-containing phytobiotic is becoming increasingly popularly utilized as antibiotic alternatives in animal production. However, their potential risks to the human health and environment remain poorly understood.
Jian-Sheng Dai, Jian Xu, Hao-Jie Shen, Ni-Pi Chen, Bing-Qi Zhu, Zheng-Jie Xue, Hao-Han Chen, Zhi-Shan Ding, Rui Ding, Chao-Dong Qian   +9 more
doaj   +1 more source

Multiple inclusion complex formation of protonated ellipticine with cucurbit[8]uril: thermodynamics and fluorescence properties [PDF]

, 2016
The encapsulation of protonated ellipticine (EH+) in the cavity of cucurbit[8]uril (CB8) was studied in water at pH 4 with spectrophotometric, fluorescence spectroscopic and isothermal calorimetric measurements.
Biczók, László, Jablonkai, István, Miskolczy, Zsombor   +2 more
core   +2 more sources

Induction of contracture and extracellular Ca2+ influx in cardiac muscle by sanguinarine: a study on cardiotoxicity of sanguinarine

Journal of Biomedical Science, 2005
In this study, the toxic effect of sanguinarine (SANG) on heart was studied with isolated cardiac muscle strip isolated from Wistar rat. SANG induced positive inotropic action followed by contracture on the left ventricle and both atria strips. In addition, SANG dose-dependently inhibited spontaneous beat of the right atrium.
Chien Ming, Hu, Yu Wen, Cheng, Jiunn Wang, Liao, Huei Wen, Cheng, Jaw Jou, Kang   +4 more
openaire   +2 more sources

CircTspan3 Promotes Cartilage Development Through ANNEXIN A2‐Mediated Ferroptosis and Apoptosis Inhibition and Exosome‐Mediated Paracrine Signaling

Advanced Science, Volume 13, Issue 10, 18 February 2026.
This study reveals that XBP1s drives production of circTspan3, a circular RNA that strengthens cartilage by boosting anabolic activity and limiting cell death. Phosphorylated ANXA2 directs circTspan3 into exosomes, enabling paracrine repair. Exosomal circTspan3 expands growth‐plate cartilage and promotes in vivo regeneration, highlighting its promise ...
Yiming Pan, Fengmei Zhang, Jiayan Zhong, Qian Gong, Nana Geng, Biao Kuang, Qiumei Lan, Miao Yi, Qiqi Zeng, Cheng Chen, Mengtian Fan, Chunliang Zhao, Deping Zeng, Yu Du, Mao Nie, Zhibiao Wang, Fengjin Guo   +16 more
wiley   +1 more source

Natural Products in Cancer Prevention and Therapy: Current Challenges and Future Directions

MedComm, Volume 7, Issue 2, February 2026.
Natural products play a pivotal role in cancer therapy. They induce cancer cell death by reprogramming four metabolic pathways while precisely targeting the tumor microenvironment and immune cells. These compounds not only leverage novel delivery systems for innovative applications but also demonstrate unique therapeutic efficacy across clinical stages:
Ruimiao Qian, Jun Ge, Ni Fan, Zheng Sun, Chengcheng Zhao, Yujiao Sun, Yingpeng Li, Yunfei Li, Hui Fu   +8 more
wiley   +1 more source