Results 71 to 80 of about 2,721 (182)

The Interference of Selected Cytotoxic Alkaloids with the Cytoskeleton: An Insight into Their Modes of Action

Molecules, 2016
Alkaloids, the largest group among the nitrogen-containing secondary metabolites of plants, usually interact with several molecular targets. In this study, we provide evidence that six cytotoxic alkaloids (sanguinarine, chelerythrine, chelidonine ...
Xiaojuan Wang, Mine Tanaka, Sonja Krstin, Herbenya Silva Peixoto, Michael Wink   +4 more
doaj   +1 more source

Sanguinarine suppresses migration and metastasis in colorectal carcinoma associated with the inversion of EMT through the Wnt/β‐catenin signaling

Clinical and Translational Medicine, 2020
Background Unresectable lung or liver organ metastases of colorectal carcinoma (CRC) remain a major obstacle in clinical therapeutics. Epithelial to mesenchymal transition (EMT), a major cause of highly frequent metastasis in tumor, can be promoted by ...
Man Zhu, Zhengyan Gong, Qing Wu, Xianpeng Shi, Qi Su, Yanmin Zhang   +5 more
doaj   +1 more source

2-(Substituted phenyl)-3,4-dihydroisoquinolin-2-iums as Novel Antifungal Lead Compounds: Biological Evaluation and Structure-Activity Relationships

Molecules, 2013
The title compounds are a class of structurally simple analogues of quaternary benzo[c]phenanthridine alkaloids (QBAs). In order to develop novel QBA-like antifungal drugs, in this study, 24 of the title compounds with various substituents on the N ...
Xin-Juan Yang, Fang Miao, Li-Fei Zhu, Cen Zhang, Rui Yang, Zhe Hou, Le Zhou   +6 more
doaj   +1 more source

Ueber das Sanguinarin [PDF]

Justus Liebigs Annalen der Chemie
n ...
openaire   +1 more source

In Vitro Study of Antitumor and Antimicrobial Activity of a Preparation of Pegylated Liposomes with Sanguinarine

Антибиотики и Химиотерапия, 2020
Sanguinarin is a plant alkaloid with a wide spectrum of biological activity. The effectiveness of sanguinarin can be increased by its integration into liposomal nanoparticles.
S. V. Lutsenko, T. I. Gromovykh, V. V. Kashirin, V. N. Kuryakov, A. A. Baranova, V. S. Sadykova, N. B. Feldman   +6 more
doaj  

Sanguinarine: a monofunctional intercalating alkaloid [PDF]

FEBS Letters, 1982
Maiti, M., Nandi, R., Chaudhuri, K.
openaire   +2 more sources

Argemone ochroleuca: (PAPAVERACEAE), ALKALOID POTENTIAL SOURCE FOR AGRICULTURAL AND MEDICINAL USES

Tropical and Subtropical Agroecosystems, 2020
Background. The genus Argemone contains 24 species, A. ochorleuca is present in national territory and is used in agriculture and traditional medical treatments for various conditions. Results. A.
Jesús Hernández-Ruiz, Julio Bernal, Jorge Eric Ruiz-Nieto, Jaquelina Gonzales-Castañeda, Ana Isabel Mireles-Arriaga   +4 more
doaj  

Sanguinarine activates ATM/ATR-mediated CHK-1 signaling to drive p53-dependent apoptosis in the C. elegans germline. [PDF]

Sci Rep
El Ghali R, Izadi M, Alrayyes Z, Vazehan R, Ali TA, Uddin S, Pourkarimi E.   +6 more
europepmc   +1 more source

Molecular docking and dynamic simulation analysis of BPTF with alkaloids. [PDF]

Bioinformation
Mammen RD, Blessy J.
europepmc   +1 more source

Antibacterial potential of danthron, embelin, sanguinarine and shikonin against multidrug-resistant Neisseria gonorrhoeae in vitro. [PDF]

Int Microbiol
Qi Y, Zhang R, Peng H, Tao C, Tang Y, Lu S, Ke Q, Shen S, Wang Z, Lin X.   +9 more
europepmc   +1 more source