Results 71 to 80 of about 5,249 (228)
Journal of Biochemical and Molecular Toxicology, Volume 39, Issue 9, September 2025.ABSTRACT We report the synthesis of four novel monoquaternary salts and four fused pyrrolo‐phenanthridine compounds, fully characterized by NMR, FT‐IR, and mass spectrometry. Guided by theoretical predictions, including molecular docking studies, we assessed their cytotoxic activity and biocompatibility.
Ashraf Al‐Matarneh +6 more
wiley +1 more source
In vitro Cytotoxic Activity of Four Plants Used in Persian Traditional Medicine [PDF]
, 2013 Purpose: The aim of this study was to investigate in vitro cytotoxic activity of four methanolic crude plant extracts against panel cell lines. Methods: Methanolic extracts were tested for their possible antitumor activity and cytotoxicity using the 3-(4,
Behzad Baradaran +3 more
core +1 more source
Sanguinarine and Its Salts [PDF]
The Boston Medical and Surgical Journaln ...
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Programmed Cell Death in Cancer
MedComm, Volume 6, Issue 9, September 2025.Cancer is one of the most common and lethal diseases globally, with programmed cell death (PCD) playing a pivotal role in its pathogenesis and treatment. This comprehensive review covers the origin, developmental trajectory, and mechanisms of various PCDs, as well as their molecular connections with cancers. Latest studies have increasingly highlighted
Yuang Wei +3 more
wiley +1 more source
Nonconventional Techniques in Plant Alkaloid Extraction: A Decade of Progress (2014–2023)
Chemistry &Biodiversity, Volume 22, Issue 8, August 2025.This figure seeks to represent the evolution of the different unconventional approaches that were adopted for the extraction of plant‐derived alkaloids during the decade from 2014 to 2023. ABSTRACT Plant metabolism encompasses primary and secondary pathways, with secondary metabolism yielding diverse natural products crucial for plant adaptation and ...
Victor Menezes Sipoloni +5 more
wiley +1 more source
Molecular isolation of cDNA encoding N-methylstylopine hydroxylase from greater celandine (Chelidonium majus L.) and its expression enhancement in response to salinity abiotic elicitor [PDF]
مجله بیوتکنولوژی کشاورزی, 2018 The greater celandine (Chelidonium majus L.) contains important alkaloids such as Sanguinarine. Sanguinarine is an active alkaloid with potentially antimicrobial, anti-inflammatory and anti-tumor properties that is widely found in plants of ...
Zahra Soleimani +2 more
doaj +1 more source
Shape-selective recognition of DNA abasic sites by metallohelices : inhibition of human AP endonuclease 1 [PDF]
, 2015 Loss of a base in DNA leading to creation of an abasic (AP) site leaving a deoxyribose residue in the strand, is a frequent lesion that may occur spontaneously or under the action of various physical and chemical agents.
Brabec, V., Malina, J., Scott, Peter
core +1 more source
Fluorescence switching of sanguinarine in micellar environments
Physical Chemistry Chemical Physics, 2015 Conversion from iminium to alkanolamine form of Sanguinarine, a key member of benzylisoquinoline alkaloid family, is monitored in micellar environments by fluorescence switch.
Sagar, Satpathi +2 more
openaire +3 more sources
Food Science &Nutrition, Volume 13, Issue 7, July 2025.Millettia speciosa Champ. is a traditional medicinal and edible plant. Its aerial parts are often discarded, leading to resource waste. HPLC‐Q‐TOF‐MS/MS analysis identified a total of 41 chemical compounds in the stems, branches, and leaves of M. speciosa. Network pharmacology screening identified Formononetin (FMN) as a key compound of M.
Wenjing Niu +4 more
wiley +1 more source
Charge Transfer-oxy Radical Mechanism for Anti-cancer Agents [PDF]
, 1986 The proposal is advanced that anti-cancer drugs generally function by charge transfer resulting in formation of toxic oxy radicals which destroy the neoplasm.
Ames, James R. +5 more
core +1 more source