Results 91 to 100 of about 5,249 (228)

Recent Developments in Deep Eutectic Solvents Applications in Liquid Chromatography: 2019–2025

open access: yesJournal of Separation Science, Volume 48, Issue 5, May 2025.
ABSTRACT Deep eutectic solvents (DES) are used as mobile phase and stationary phase modifiers, or as for the stationary phase itself for thin layer/liquid/supercritical chromatography. Their specific properties can improve the separation selectivity, reduce peak tailing, and shorten the separation time.
Derya Demir   +3 more
wiley   +1 more source

GAME9 regulates the biosynthesis of steroidal alkaloids and upstream isoprenoids in the plant mevalonate pathway [PDF]

open access: yes, 2016
Steroidal glycoalkaloids (SGAs) are cholesterol-derived molecules produced by solanaceous species. They contribute to pathogen defence but are toxic to humans and considered as anti-nutritional compounds.
Aharoni, Asaph   +13 more
core   +1 more source

Natural products targeting tumour angiogenesis

open access: yesBritish Journal of Pharmacology, Volume 182, Issue 10, Page 2094-2136, May 2025.
Abstract Tumour angiogenesis is the formation of new blood vessels to support the growth of a tumour. This process is critical for tumour progression and metastasis, making it an attractive approach to cancer therapy. Natural products derived from plants, animals or microorganisms exert anti‐angiogenic properties and can be used to inhibit tumour ...
Xiaohua Lu   +2 more
wiley   +1 more source

Sanguinarine Induces Apoptosis in Papillary Thyroid Cancer Cells via Generation of Reactive Oxygen Species

open access: yesMolecules, 2020
Sanguinarine (SNG), a natural compound with an array of pharmacological activities, has promising therapeutic potential against a number of pathological conditions, including malignancies.
Abdul Q. Khan   +10 more
doaj   +1 more source

Ethnobotanical study and pharmacological properties of Chelidonium Majus [PDF]

open access: yes, 2016
Chelidonium Majusto the plant family of Asteraceae, native to temperate Asia, but naturalized in many countries including scattered parts of North America.
Miraj, S.
core  

Technology differentiation, product market rivalry, and M&A transactions

open access: yesStrategic Management Journal, Volume 46, Issue 4, Page 837-862, April 2025.
Abstract Research Summary We study how unique firm technology influences M&A activity. Using a text‐based network approach, we map each firm's position relative to every other firm in technology space to measure the uniqueness of its technology portfolio.
Sam Arts, Bruno Cassiman, Jianan Hou
wiley   +1 more source

The Multifaceted Roles of BACH1 in Disease: Implications for Biological Functions and Therapeutic Applications

open access: yesAdvanced Science, Volume 12, Issue 10, March 13, 2025.
BACH1, a basic leucine zipper protein ubiquitously expressed in mammalian tissues, plays a critical role in the regulation of oxidative stress, cell cycle progression, heme homeostasis, and immune responses. It is implicated in cardiovascular diseases, cancer progression, neurodegenerative disorders, and many other diseases.
Xiangxiang Wei   +9 more
wiley   +1 more source

Phytochemical Analysis and Antimicrobial Efficacy of against Extensively Drug-Resistant

open access: yesNatural Product Communications, 2018
The antibiotic resistant threat is continuing to grow, due in part to the overuse of antibiotics in livestock feed. Many nations in Europe have banned the use of antibiotics in feed, leading to higher rates of infection in livestock animals and reduced ...
Manead Khin   +3 more
doaj   +1 more source

The Interference of Selected Cytotoxic Alkaloids with the Cytoskeleton: An Insight into Their Modes of Action

open access: yesMolecules, 2016
Alkaloids, the largest group among the nitrogen-containing secondary metabolites of plants, usually interact with several molecular targets. In this study, we provide evidence that six cytotoxic alkaloids (sanguinarine, chelerythrine, chelidonine ...
Xiaojuan Wang   +4 more
doaj   +1 more source

Sanguinarine suppresses migration and metastasis in colorectal carcinoma associated with the inversion of EMT through the Wnt/β‐catenin signaling

open access: yesClinical and Translational Medicine, 2020
Background Unresectable lung or liver organ metastases of colorectal carcinoma (CRC) remain a major obstacle in clinical therapeutics. Epithelial to mesenchymal transition (EMT), a major cause of highly frequent metastasis in tumor, can be promoted by ...
Man Zhu   +5 more
doaj   +1 more source

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