Results 61 to 70 of about 3,726 (205)
Frontiers in Veterinary Science, 2023 Staphylococcus aureus (SA) is representative of gram-positive bacteria. Sanguinarine chloride hydrate (SGCH) is the hydrochloride form of sanguinarine (SG), one of the main extracts of Macleaya cordata (M. cordata).
Yeqing Gu +12 more
doaj +1 more source
C4 Functionalization of the Isoquinoline Core via Oxidative Radical Substitution
ChemistrySelect, Volume 11, Issue 21, 4 June 2026.The isoquinoline ring can be easily functionalized at C‐4 through a radical‐oxidative substitution process. The resulting products can be readily cyclized under basic conditions, facilitating the construction of pyranones fused to the isoquinoline scaffold. ABSTRACTIn this work, we report a straightforward synthetic procedure that enables the selective
Oscar Coral +2 more
wiley +1 more source
Antitumor effects of the benzophenanthridine alkaloid sanguinarine: Evidence and perspectives [PDF]
, 2016 Historically, natural products have represented a significant source of anticancer agents, with plant-derived drugs becoming increasingly explored.
PICA, FRANCESCA +9 more
core +1 more source
The effect of sanguinarine on the RPMI-7951 and A375 melanoma cell lines [PDF]
, 2023 Background: Considering the resistance of melanoma to standard treatment protocols, the possibility of metastasis and the high mortality risk, the selection of new alternatives seems to be necessary.
Izdebska, Magdalena; Departament of Histology and Embryology, Nicolas Copernicus University in Torun, Faculty of Medicine, Collegium Medicum in Bydgoszcz, Poland +5 more
core +1 more source
Fluorescence switching of sanguinarine in micellar environments
Physical Chemistry Chemical Physics, 2015 Conversion from iminium to alkanolamine form of Sanguinarine, a key member of benzylisoquinoline alkaloid family, is monitored in micellar environments by fluorescence switch.
Sagar, Satpathi +2 more
openaire +3 more sources
Advanced Science, Volume 13, Issue 21, 13 April 2026.ABSTRACT The rising incidence of chronic diseases globally has drawn widespread attention to phytochemicals, which exert targeted preventive and alleviating effect by modulating gut microbiota; thus, a potential strategy for precision nutritional interventions is offered.
Shiqi Bai +6 more
wiley +1 more source
Reducing the Sinapine Levels of Camelina sativa Seeds Through Targeted Genome Editing of REF1
Plant Biotechnology Journal, Volume 24, Issue 3, Page 1839-1865, March 2026.ABSTRACT Sinapine (O‐sinapoyl choline) is the major phenolic metabolite typically found in the oil‐rich seeds of Brassicaceae such as Camelina sativa and Brassica napus. It imparts a bitter taste to the seeds as a defence mechanism against herbivores, but it also renders them less palatable to livestock.
Amélie A. Kelly +5 more
wiley +1 more source
Advanced Science, Volume 13, Issue 10, 18 February 2026.This study reveals that XBP1s drives production of circTspan3, a circular RNA that strengthens cartilage by boosting anabolic activity and limiting cell death. Phosphorylated ANXA2 directs circTspan3 into exosomes, enabling paracrine repair. Exosomal circTspan3 expands growth‐plate cartilage and promotes in vivo regeneration, highlighting its promise ...
Yiming Pan +16 more
wiley +1 more source
Promoting Effects of Sanguinarine on Apoptotic Gene Expression in Human Neuroblastoma Cells
, 2014 Neuroblastoma is the most common extracranial solid tumor in children. Approximately half of the affected patients are diagnosed with high-risk poor prognosis disease, and novel therapies are needed.
Zekiye Altun +9 more
core +1 more source
Natural Products in Cancer Prevention and Therapy: Current Challenges and Future Directions
MedComm, Volume 7, Issue 2, February 2026.Natural products play a pivotal role in cancer therapy. They induce cancer cell death by reprogramming four metabolic pathways while precisely targeting the tumor microenvironment and immune cells. These compounds not only leverage novel delivery systems for innovative applications but also demonstrate unique therapeutic efficacy across clinical stages:
Ruimiao Qian +8 more
wiley +1 more source