Results 11 to 20 of about 5,249 (228)

Supra and subgingival application of antiseptics or antibiotics during periodontal therapy

open access: yesPeriodontology 2000, EarlyView., 2023
Abstract Periodontal diseases (gingivitis and periodontitis) are characterized by inflammatory processes which arise as a result of disruption of the balance in the oral ecosystem. According to the current S3 level clinical practice guidelines, therapy of patients with periodontitis involves a stepwise approach that includes the control of the patient ...
Elena Figuero   +5 more
wiley   +1 more source

Sanguinarine Regulates Tumor-Associated Macrophages to Prevent Lung Cancer Angiogenesis Through the WNT/β-Catenin Pathway

open access: yesFrontiers in Oncology, 2022
Tumor-associated macrophage (TAM)-mediated angiogenesis in the tumor microenvironment is a prerequisite for lung cancer growth and metastasis. Therefore, targeting TAMs, which block angiogenesis, is expected to be a breakthrough in controlling the growth
Yajing Cui   +8 more
doaj   +1 more source

Sanguinarine synergistically potentiates aminoglycoside‐mediated bacterial killing

open access: yesMicrobial Biotechnology, 2022
Summary Aminoglycosides are one of the oldest classes of antimicrobials that are being used in current clinical practice, especially on multi‐drug resistant Gram‐negative pathogenic bacteria.
Chang Lu   +6 more
doaj   +1 more source

In vitro Anti-Inflammatory Potency of Sanguinarine and Chelerythrine via Interaction with Glucocorticoid Receptor

open access: yeseFood, 2021
As quaternary benzo[c]phenanthridine alkaloids, sanguinarine and chelerythrine possess multiple biological activities including anti-inflammatory effects.
Jie Zhang   +3 more
doaj   +1 more source

Biosynthesis of Antitumoral and Bactericidal Sanguinarine [PDF]

open access: yesBioMed Research International, 2006
A simple, rapid, and reliable TLC method for the separation and determination of sanguinarine has been established. This intensively studied biologically active alkaloid has a wide range of potentially useful medicinal properties, such as antimicrobial, antiinflammatory, and antitumoral activities.
García, Víctor P.   +5 more
openaire   +2 more sources

Sanguinarine modulate gut microbiome and intestinal morphology to enhance growth performance in broilers.

open access: yesPLoS ONE, 2020
Sanguinarine is a bioactive compound as a quaternary benzophenanthridine alkaloid from plant of the Macleaya cordata, Papaveraceae family. The present study was conducted to investigate the effects of dietary sanguinarine supplementation on growth ...
Zhu-Ying Liu   +4 more
doaj   +1 more source

Development and validation of a luminescence-based, medium-throughput assay for drug screening in Schistosoma mansoni [PDF]

open access: yes, 2015
Schistosomiasis, one of the world's greatest neglected tropical diseases, is responsible for over 280,000 human deaths per annum. Praziquantel, developed in the 1970s, has high efficacy, excellent tolerability, few and transient side effects, simple ...
Altamura, Sergio   +5 more
core   +3 more sources

Sanguinarine

open access: yesCardiovascular Drug Reviews, 2008
Sanguinarine is an alkaloid found in many medicinal plants. It has diverse biological activities, including modulation of nuclear factor‐κB and of several enzymes. It is also known to induce apoptosis, perturb microtubules, and to have antimicrobial effects.
I, Mackraj   +2 more
openaire   +2 more sources

The allelopathic algicides sanguinarine and berberine reduced the dominance of Microcystis in competition with Chlorella

open access: yesResults in Engineering, 2022
Gramine, sanguinarine and berberine are potential algicides that can significantly inhibit the growth of cyanobacteria. Their effects on other phytoplankton have to be considered, because other phytoplankton species and cyanobacteria usually co-exist. In
Pengfei Duan   +3 more
doaj   +1 more source

Sanguinarine Reverses Pulmonary Vascular Remolding of Hypoxia-Induced PH via Survivin/HIF1α-Attenuating Kv Channels

open access: yesFrontiers in Pharmacology, 2021
Background: Similarities in the biology of pulmonary hypertension and cancer suggest that anticancer therapies, such as sanguinarine, may also be effective in treating pulmonary hypertension.
Fenling Fan   +7 more
doaj   +1 more source

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