Results 21 to 30 of about 5,249 (228)

MKP1 mediates resistance to therapy in HER2-positive breast tumors. [PDF]

open access: yes, 2015
Mitogen-activated protein kinase phosphatase 1 (MKP1 or DUSP1) is an antiapoptotic phosphatase that is overexpressed in many cancers, including breast cancer.
Candas, Demet, Li, Jian Jian
core   +2 more sources

Influence of sanguinarine-based phytobiotic supplementation on post necrotic enteritis challenge recovery

open access: yesHeliyon, 2020
In the animal production industry, plant-derived antimicrobial phytobiotics are used as an alternative to antibiotics. Here we investigated the role sanguinarine-based phytobiotic in broiler recovery from Necrotic Enteritis (NE) infection. A total of 100
Mashael R. Aljumaah   +7 more
doaj   +1 more source

Screening of isoquinoline alkaloids for potent lipid metabolism modulation with Caenorhabditis elegans. [PDF]

open access: yes, 2013
Metabolic syndrome and related disorders are increasingly prevalent in contemporary society, and thus pose the need for potent agents to control lipid accumulation in the body.
Chow, Yit-Lai, Sato, Fumihiko
core   +1 more source

Sanguinarine Exhibits Antiviral Activity against Porcine Reproductive and Respiratory Syndrome Virus via Multisite Inhibition Mechanisms

open access: yesViruses, 2023
Porcine reproductive and respiratory syndrome virus (PRRSV), the etiological agent of PRRS, is prevalent worldwide, causing substantial and immense economic losses to the global swine industry.
Qiyun Ke   +5 more
doaj   +1 more source

Inhibition of mouse liver respiration by Chelidonium majus isoquinoline alkaloids [PDF]

open access: yes, 2003
Copyright © 2003 Elsevier Ireland Ltd. All rights reserved.The alkaloids from Chelidonium majus L. which had a significant inhibitory effect in mitochondrial respiration were those which contain a positive charge due to a quaternary nitrogen atom, i.e ...
Arrabaça, João Daniel   +3 more
core   +1 more source

Microchip electrophoresis bioanalytical applications [PDF]

open access: yes, 2008
Microchip electrophoresis (MCE) is a novel analytical technique resulting from miniaturization of capillary electrophoresis (CE) to a planar microfabricated separation device.
Vlcková, Markéta
core   +1 more source

S-adenosyl-l-methionine: (S) -7,8,13, 14-tetrahydroberberine--n-methyltransferase, a branch point enzyme in the biosynthesis of benzophenanthridine and protopine alkaloids. [PDF]

open access: yes, 1986
The enzyme which transfers the CH3-group of S-adenosylmethionine to the nitrogen atom of (S)-tetrahydroberberine and (S)-stylopine is found to occur in a number of plant cell cultures originating from species containing alkaloids; it is located at an ...
Amann   +8 more
core   +1 more source

The Challenges and Opportunities of lncRNAs in Ovarian Cancer Research and Clinical Use [PDF]

open access: yes, 2020
[Abstract] Ovarian cancer is one of the most lethal gynecological malignancies worldwide because it tends to be detected late, when the disease has already spread, and prognosis is poor.
Barreiro-Alonso, Aida   +6 more
core   +1 more source

Sanguinarine triggers intrinsic apoptosis to suppress colorectal cancer growth through disassociation between STRAP and MELK

open access: yesBMC Cancer, 2018
Background Previous studies showed sanguinarine induced apoptosis in CRC cells but did not define the underlying mechanisms. The purpose of this work was to determine the in vivo and in vitro effects of sanguinarine on CRC tumors and to elucidate the ...
Xianling Gong   +8 more
doaj   +1 more source

Sanguinarine Inhibits Mono- and Dual-Species Biofilm Formation by Candida albicans and Staphylococcus aureus and Induces Mature Hypha Transition of C. albicans

open access: yesPharmaceuticals, 2020
Previous studies have reported that sanguinarine possesses inhibitory activities against several microorganisms, but its effects on mono- and dual-species biofilms of C. albicans and S. aureus have not been fully elucidated.
Weidong Qian   +7 more
doaj   +1 more source

Home - About - Disclaimer - Privacy