Results 51 to 60 of about 9,197 (244)

Metabolomics Analysis of the Effects of Chelerythrine on Ustilaginoidea virens [PDF]

open access: yes, 2022
Abstract Background: Rice false smut (RFS), caused by Ustilaginoidea virens, is widely distributed in major rice-producing regions. Previous studies showed that treating RFS with chelerythrine can decrease fungus spore germination by 86.7% and induce fungal cell apoptosis.
Qinghui Wei   +6 more
openaire   +1 more source

Coronavirus disease 2019 (COVID-19), human erythrocytes and the PKC-alpha/-beta inhibitor chelerythrine –possible therapeutic implication

open access: yesCell Cycle, 2020
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes COVID-19. Until now, diverse drugs have been used for the treatment of COVID-19. These drugs are associated with severe side effects, e.g.
Mehrdad Ghashghaeinia   +3 more
semanticscholar   +1 more source

Natural Alkaloids in Cancer Therapy: Berberine, Sanguinarine and Chelerythrine against Colorectal and Gastric Cancer

open access: yesInternational Journal of Molecular Sciences
The rising incidence of colorectal cancer (CRC) and gastric cancer (GC) worldwide, coupled with the limited effectiveness of current chemotherapeutic agents, has prioritized the search for new therapeutic options.
Anna Duda-Madej   +3 more
semanticscholar   +1 more source

Structure-activity relationship of benzophenanthridine alkaloids from Zanthoxylum rhoifolium having antimicrobial activity.

open access: yesPLoS ONE, 2014
Zanthoxylum rhoifolium (Rutaceae) is a plant alkaloid that grows in South America and has been used in Brazilian traditional medicine for the treatment of different health problems. The present study was designed to evaluate the antimicrobial activity of
Luciana de C Tavares   +9 more
doaj   +1 more source

Kinetic characterization of ebselen, chelerythrine and apomorphine as glutaminase inhibitors [PDF]

open access: yesBiochemical and Biophysical Research Communications, 2013
Glutaminase catalyzes the hydrolysis of glutamine to glutamate and plays a central role in the proliferation of neoplastic cells via glutaminolysis, as well as in the generation of excitotoxic glutamate in central nervous system disorders such as HIV-associated dementia (HAD) and multiple sclerosis.
Ajit G, Thomas   +9 more
openaire   +2 more sources

Analysis of benzo[c] phenanthridine alkaloids in Eschscholtzia californica cell culture using HPLC-DAD and HPLC-ESI-MS/MS [PDF]

open access: yes, 2014
Effective HPLC-DAD and HPLC-ESI-MS/MS methods have been developed for the analysis of eight benzo[c] phenanthridine alkaloids (sanguinarine, chelirubine, macarpine, chelerythrine, dihydrosanguinarine, dihydrochelirubine, dihydromacarpine and ...
Hong Soon Rhee   +4 more
core   +1 more source

Isolation, Identification, Modification, and Biological Analysis of extracts of A. Mexicana [PDF]

open access: yes, 2020
Argemone mexicana is a member of the Papaveraceae family of plants that has been used for centuries in traditional medicine by indigenous communities in Mexico and the United States.
Lefeber, Theodore   +3 more
core   +1 more source

The specific PKC-α inhibitor chelerythrine blunts costunolide-induced eryptosis

open access: yesApoptosis, 2020
Costunolide, a natural sesquiterpene lactone, has multiple pharmacological activities such as neuroprotection or induction of apoptosis and eryptosis.
Mehrdad Ghashghaeinia   +13 more
semanticscholar   +1 more source

Traditional Chinese Medicine for lung cancer: Mechanisms, clinical evidence, and future perspectives

open access: yesPrecision Medical Sciences, EarlyView.
Graphical abstract represents the risk factors for lung cancer, TCM efficacy and clinical outcomes to future challenges. Abstract Lung cancer remains a leading cause of global cancer mortality. Despite advances in conventional treatments such as surgery, chemotherapy, targeted therapy, and immunotherapy, challenges including drug resistance, toxicity ...
Zhangdeng Chen, Liujun Bao
wiley   +1 more source

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