Results 21 to 30 of about 3,120 (165)

Using Liposomes to Alleviate the Toxicity of Chelerythrine, a Natural PKC Inhibitor, in Treating Non-Small Cell Lung Cancer

Frontiers in Oncology, 2021
Aim of the StudyCHE can inhibit the proliferation of lung cancer cells and induce apoptosis. However, despite having in vivo toxicity, CHE has not been thoroughly investigated in term of its in vivo antitumor effect.
Jiahui Wang, Jiahui Wang, Yijie Song, Yijie Song, Ning Zhang, Ning Li, Congying Liu, Bing Wang, Bing Wang   +8 more
doaj   +1 more source

Efficacy of Chelerythrine Against Mono- and Dual-Species Biofilms of Candida albicans and Staphylococcus aureus and Its Properties of Inducing Hypha-to-Yeast Transition of C. albicans

Journal of Fungi, 2020
Candida albicans and Staphylococcus aureus specifically often resulted in biofilm-associated diseases, ranging from superficial mucosal to life-threatening systemic infections. Recent studies reported that chelerythrine displayed antimicrobial activities
Weidong Qian, Jianing Zhang, Wenjing Wang, Miao Liu, Yuting Fu, Xiang Li, Ting Wang, Yongdong Li   +7 more
doaj   +1 more source

Fluorescence, Absorption, Chromatography and Structural Transformation of Chelerythrine and Ethoxychelerythrine in Protic Solvents: A Comparative Study

Molecules, 2022
Chelerythrine (CH) and ethoxychelerythrine (ECH) are chemical reference substances for quality control of Chinese herbal medicines, and ECH is the dihydrogen derivative of CH.
Jinjin Cao, Yanhui Zheng, Ting Liu, Jiamiao Liu, Jinze Liu, Jing Wang, Qirui Sun, Wenhong Li, Yongju Wei   +8 more
doaj   +1 more source

Antibacterial mechanism of chelerythrine isolated from root of Toddalia asiatica (Linn) Lam

BMC Complementary and Alternative Medicine, 2018
Background Antimicrobial resistance was one of serious worldwide problems confused many researchers. To solve this problem, we explored the antibacterial effect of chelerythrine, a natural compound from traditional Chinese medicine and studied its action.
Nan He, Peiqing Wang, Pengyu Wang, Changyang Ma, Wenyi Kang   +4 more
doaj   +1 more source

Antitumor Effects of Chelerythrine: A Literature Review

Natural Product Communications, 2022
Chelerythrine (CHE), one of the main active components of the medicinal plant, Chelidonium majus, (Figure 1) Botanical authority is traditionally used as a natural medicine for its significant antitumor activity. The relevant literature on the antitumor activity of CHE has been reviewed to provide a theoretical basis for further study and utilization ...
Kai Kang, Hanbing Jiang, Shujun Zhang, Binglin Cheng   +3 more
openaire   +1 more source

EFFECTS OF SANGUINARINE AND CHELERYTHRINE ON THE CELL CYCLE AND APOPTOSIS [PDF]

Biomedical Papers, 2006
This review summarizes the involvement of sanguinarine and chelerythrine in cell cycle regulation and cell death in various cell lines. It is focused on their potential in the treatment of cancer.We conducted a search of PubMed, ScienceDirect and Medline for papers on the molecular mechanisms of the biological activity of sanguinarine and chelerythrine
Jana, Malikova, Adela, Zdarilova, Alice, Hlobilkova   +2 more
openaire   +2 more sources

Chelerythrine Chloride Downregulates β-Catenin and Inhibits Stem Cell Properties of Non-Small Cell Lung Carcinoma

Molecules, 2020
Plant secondary metabolites have been seen as alternatives to seeking new medicines for treating various diseases. Phytochemical scientists remain hopeful that compounds isolated from natural sources could help alleviate the leading problem in oncology ...
Win Sen Heng, Shiau-Chuen Cheah
doaj   +1 more source

Separation and Preparation of Sanguinarine and Chelerythrine from Macleaya cordata Root by High Speed Counter-Current Chromatography

Shipin gongye ke-ji, 2022
The aim of this study was to develop a method for the separation and preparation of high purity sanguinarine and chelerythrine by conventional high speed counter-current chromatography.
Changqing JIA, Rui MA, Xicheng QIAN, Dandan WANG, Jiansheng YU   +4 more
doaj   +1 more source

Chelerythrine-Induced Apoptotic Cell Death in HepG2 Cells Involves the Inhibition of Akt Pathway and the Activation of Oxidative Stress and Mitochondrial Apoptotic Pathway

Antioxidants, 2022
Chelerythrine (CHE) is a majorly harmful isoquinoline alkaloid ingredient in Chelidonium majus that could trigger potential hepatotoxicity, but the pivotal molecular mechanisms remain largely unknown.
Yanling Lin, Qinzhi Zhang, Baofu Xie, Haiyang Jiang, Jianzhong Shen, Shusheng Tang, Chongshan Dai   +6 more
doaj   +1 more source

Über Chelerythrin [PDF]

Berichte der deutschen chemischen Gesellschaft, 1917
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openaire   +2 more sources