Results 11 to 20 of about 4,409 (215)

Quantitative Correlation Between Charge Transfer and Two Photon Absorption in Phenanthridine‐TCNB Cocrystal

Information & Functional Materials
Charge transfer (CT) in organic donor‐acceptor (D‐A) systems is a spin‐allowed thermodynamic process. It creates new energetic landscapes and fundamentally decides charge photogeneration and transport, luminescent, nonlinear optical (NLO), and magnetic ...
Weigang Zhu, Ying Ni, Bin Li, Rafael C. González‐Cano, Wenping Hu   +4 more
doaj   +2 more sources

Uracil-Peptide-Pyrene Conjugates as Cu²⁺-Sensitive Probes Targeting DNA, RNA, and Biorelevant Model Membranes. [PDF]

Chembiochem
We introduce uracil–triazole–pyrene peptidomimetics whose tunable peptide linkers precisely control light emission, copper binding, and interactions with DNA and RNA. Fine structural adjustments unlock selective biomolecular recognition and striking metal‐ and membrane‐responsive fluorescence, paving the way for a new generation of multifunctional ...
Pavlović Saftić D, Lulić Horvat L, Piantanida I.   +2 more
europepmc   +2 more sources

Pyrrolo-Fused Phenanthridines as Potential Anticancer Agents: Synthesis, Prediction, and Biological Evaluation. [PDF]

J Biochem Mol Toxicol
ABSTRACT We report the synthesis of four novel monoquaternary salts and four fused pyrrolo‐phenanthridine compounds, fully characterized by NMR, FT‐IR, and mass spectrometry. Guided by theoretical predictions, including molecular docking studies, we assessed their cytotoxic activity and biocompatibility.
Al-Matarneh A, Simionescu N, Nicolescu A, Cibotariu N, Danac R, Al-Matarneh MC, Mangalagiu II.   +6 more
europepmc   +2 more sources

In Pursuit of Low Energy Phosphorescence: Late Metal Coordination Complexes of the Planar, π-extended Bipyridyl Ligand 6,6',7,7'-Biphenanthridine. [PDF]

Chemistry
Abstract The coordination chemistry of the planar, doubly π‐extended bipyridine analog, 6,6′,7,7′‐biphenanthridine (p‐biphe), is presented. The phenanthridine units in p‐biphe are fused together at the 6‐ and 7‐ positions, and the resulting rigid ligand is compared with the more flexible parent “biphe” fused only at the 6‐positions.
Nemez DB, Ortiz RJ, Veilleux KA, Williams JAG, Herbert DE.   +4 more
europepmc   +2 more sources

Dual Targeting of DNA and EGFR by ZYH005 Induces DNA Damage and Mitotic Catastrophe in Glioblastoma. [PDF]

MedComm (2020)
ZYH005 exerts potent anti‐glioblastoma activity through a dual mechanism: intercalation‐mediated DNA damage and targeted inhibition of EGFR, leading to cell cycle arrest and mitotic catastrophe. ABSTRACT Glioblastoma multiforme (GBM) is an aggressive, therapy‐resistant brain tumor with limited treatment options.
Huang J, Zhang Z, Xiao Y, Zhao Z, Luo Z, Liu J, Lai S, Song C, Feng S, Zhang S, Yu X, Tong Q, Zhang Y.   +12 more
europepmc   +2 more sources

The electronic spectra of protonated PANH molecules [PDF]

, 2015
Aims. This study was designed to examine the viability of protonated nitrogen-substituted polycyclic aromatic hydrocarbons (H+PANHs) as candidates for the carriers of the diffuse interstellar bands (DIBs). Methods.
Dedonder, C., Jouvet, C., Noble, J. A.
core   +3 more sources

Microwave assisted synthesis of phenanthridine derivatives via Suzuki coupling and condensation

Results in Chemistry, 2021
One-pot synthesis of phenanthridine derivatives using appropriately substituted aromatic ortho-bromo N-tosylhydrazones and 2′-aminobenzeneboronic acid pinacol esters is described.
Satheesh Kumar Dende, Raghu Babu Korupolu, Raju Doddipalla, Krishnakanth Reddy Leleti   +3 more
doaj   +1 more source

A novel phenanthridine and terpyridine based D-π-A fluorescent probe for the ratiometric detection of Cd2+ in environmental water samples and living cells

Ecotoxicology and Environmental Safety, 2022
A “turn-on” Donor-π-Acceptor (D-π-A) containing phenanthridine-functionalized extended π-conjugate terpyridine, 5-(4′-([2,2′:6′,2''-terpyridin]−4′-yl)-[1,1′-biphenyl]4-yl)7,8,13,14-tetrahydrodibenzo [a, i] phenanthridine (TBTP) was synthesised.
Saravanan Enbanathan, Sathiyanarayanan Kulathu Iyer   +1 more
doaj   +1 more source

Discovery of potent histone deacetylase inhibitors with modified phenanthridine caps

Journal of Enzyme Inhibition and Medicinal Chemistry, 2021
In discovery of novel HDAC inhibitory with anticancer potency, pharmacophores of phenanthridine were introduced to the structure of HDAC inhibitors. Fatty and aromatic linkers were evaluated for their solubility and activity.
Wenli Fan, Lin Zhang, Xuejiang Wang, Haiyong Jia, Lei Zhang   +4 more
doaj   +1 more source

Potential dietary feed additives with antibacterial effects and their impact on performance of weaned piglets: A meta-analysis [PDF]

, 2019
This meta-analysis evaluated the use of potential dietary feed additives (pDFA) with antibacterial effects and their impact on the perfomance of weaned piglets.
Bruggeman, G., Dewulf, J., Papadopoulos, D., Sarrazin, S., Tanghe, S., Trevisi, P., Vanrolleghem, W., Verstringe, S., Zentek, J.   +8 more
core   +5 more sources