Results 81 to 90 of about 4,409 (215)

Rapid Access to Emission‐Tunable Organelle‐Targeted Aggregation‐Induced Emission Luminogens Through One‐Pot Skeletal Editing

Transformative Chemistry, Volume 1, Issue 1, December 2025.
Herein we report a skeletal editing strategy for rapidly transforming readily available isoquinolines into synthetically challenging (dihydrodibenzo[c,i]phenanthridin‐6‐yl)diphenylphosphine oxides (DHBPPO) derivatives. These DHBPPO derivatives exhibit tunable emission, aggregation‐induced emission (AIE) properties, organelle‐targeted specificity, and ...
Yanling Liu, Chaoyang Li, Yunlong Qin, Yifan Cheng, Jianing Zhang, Yang Zhao, Tianhao Wu, Chenghan He, Cheng Xu, Qilin Wang, Zheng Zhao, Ben Zhong Tang   +11 more
wiley   +1 more source

An investigation of a palladium catalysed biaryl synthesis of pyrrolophenanthridine derivatives. Extension of the Heck reaction

Journal of the Brazilian Chemical Society, 2000
N-Benzylisatin derivatives have been found to readily undergo cyclisation via hydrogen halide elimination in a biaryl synthesis reaction when using palladium catalysts, in the absence of phosphine ligands, to yield oxopyrrolo[3,2,1-de]phenanthridine ...
Garden Simon J., Torres José C., Pinto Angelo C.   +2 more
doaj  

QSAR Modeling on Benzo[<em>c</em>]phenanthridine Analogues as Topoisomerase I Inhibitors and Anti-cancer Agents

Molecules, 2012
Benzo[<em>c</em>]phenanthridine (BCP) derivatives were identified as topoisomerase I (TOP-I) targeting agents with pronounced antitumor activity.
Thi-Ngoc-Phuong Huynh, Thanh-Dao Tran, Quang-Huynh Bui, Khac-Minh Thai   +3 more
doaj   +1 more source

Expanding the palette of phenanthridinium cations [PDF]

, 2014
5,6-Disubstituted phenanthridinium cations have a range of redox, fluorescence and biological properties. Some properties rely on phenanthridiniums intercalating into DNA, but the use of these cations as exomarkers for the reactive oxygen species (ROS ...
Acevedo, Amann, Amatore, Amii, Augustine, Barluenga, Blanchot, Blanksby, Bolognesi, Bourne, Bourne, Bourne, Chen, Cheng, Chiavarino, Chiavarino, Chéron, Coe, Darzynkiewicz, Deb, Diaba, Dimiza, Döbele, Exner, Fernández, García, Ghaneolhosseini, Giroldo, Glendening, Glendening, Glendening, Glukhovtsev, Goerigk, Goryunov, Hata, Hu, Huang, Huber, Ihmels, Intrieri, Ishihara, Ishii, Jain, Jankowiak, Jones, Jose, Kitson, Korotvicka, Kostiainen, Kubar, Kundu, Lallana, Lee, Leupin, Lewis, Liang, Liljenberg, Liljenberg, Liljenberg, Liu, Liu, Logan, Luedtke, Luedtke, Manetsch, Marivingt-Mounir, Marivingt-Mounir, Mayer, McBurney, Michalski, Michels, Molander, Nakanishi, O′Brien, O′Connor, Parenty, Park, Pliego, Prunkl, Radic, Rangarajan, Richmond, Robinson, Schmidt, Shaw, Sletten, Smith, Sotomayor, Stevens, Stojkovic, Sumerlin, Sun, Suzuki, Takeda, Tanaka, Tanaka, Tobisu, van der Wiel, Veale, Wainwright, Wakelin, Walls, Watkins, Weigend, Weinhold, Weinhold, Wolff, Yamaguchi, Zhang, Zhao, Zhao, Zhidkov, Zhidkov, Zielonka, Zille   +114 more
core   +4 more sources

In Vitro Antifungal Activity of Sanguinarine and Chelerythrine Derivatives against Phytopathogenic Fungi

Molecules, 2012
In order to understand the antifungal activity of some derivatives of sanguinarine (S) and chelerythrine (C) and their structure-activity relationships, sixteen derivatives of S and C were prepared and evaluated for in vitro antifungal activity against ...
Yan-Ni Ma, Bao-Fu Qin, Rui Yang, Fang-Jun Cao, Yao Yao, Fang Miao, Xin-Juan Yang, Le Zhou   +7 more
doaj   +1 more source

One-pot multi-reaction processes: synthesis of natural products and drug-like scaffolds [PDF]

, 2014
One-pot multi-reaction processes involving Overman rearrangements, metathesis cyclizations, and Diels–Alder reactions have been developed for the rapid and efficient synthesis of amino-substituted carbocyclic and heterocyclic compounds.
Calder, Ewen D.D., Grafton, Mark W., Sutherland, Andrew   +2 more
core   +1 more source

Multistep Reactions Initiated by Amine‐Based Organometallic Methods

European Journal of Organic Chemistry, Volume 28, Issue 40, October 29, 2025.
The advent of C–H activation and other organometallic methodologies making use of transient directing groups or free amines themselves for the elaboration of amine substrates provides unique access to cascade‐type reactions that can generate significant molecular complexity in one pot. The pursuit of atom‐ and step‐economical pathways to access complex
Victoria D. Ho, Olutayo N. Farinde, Kendra K. Shrestha, Michael C. Young   +3 more
wiley   +1 more source

Polyanionic Biopolymers for the Delivery of Pt(II) Cationic Antiproliferative Complexes

Bioinorganic Chemistry and Applications, 2016
Phenanthriplatin, that is, (SP-4-3)-diamminechlorido(phenanthridine)platinum(II) nitrate, an effective antitumor cationic Pt(II) complex, was loaded on negatively charged dextran sulfate (DS) as a model vector for drug delivery via electrostatic ...
Mauro Ravera, Elisabetta Gabano, Ilaria Zanellato, Elena Perin, Aldo Arrais, Domenico Osella   +5 more
doaj   +1 more source

Understanding and Improving Platinum Anticancer Drugs - Phenanthriplatin [PDF]

, 2013
Approximately half of all patients who receive anticancer chemotherapy are treated with a platinum drug. Despite the widespread use of these drugs, the only cure that can be claimed is that of testicular cancer following cisplatin treatment. This article
Johnstone, Timothy, Lippard, Stephen J., Park, Ga Young   +2 more
core   +1 more source

Complexation of norfloxacin with DNA in the presence of caffeine [PDF]

, 2006
1H NMR spectroscopy (500 MHz) has been used to quantify the complexation of the antibacterial antibiotic Norfloxacin (NOR) with DNA in the presence of Caffeine (CAF). Separate studies have been made for the self-association of NOR, its hetero-association
Davies, David B., Evstigneev, M.P., Rybakova, K.A.   +2 more
core   +1 more source