Results 21 to 30 of about 1,085 (145)
Synthesis and Characterization of Carbazole‐Containing Aza[7]helicenes
Double ortho fusion led to different aza[7]helicene frameworks showing strong acidochromic behavior, singlet excited energies being more than twice the triplet energy, and high racemization barriers, allowing chiral resolution and ECD measurements. ABSTRACT Azahelicenes have attracted significant interest due to their intrinsic axial chirality and ...
Inka Marten +2 more
wiley +1 more source
Mo‐Catalyzed Synthesis of N‐Polyheterocycles From Functionalized Nitroarenes and Aldehydes
Mo(VI)‐catalyzed one‐pot conversion of readily available functionalized nitroarenes and aldehydes yielded fused N‐polyheterocycles by sequential nitro reduction, imine formation, and cyclization. Using pinacol as a benign reductant, this sustainable tandem strategy suppresses side reactions and grants rapid access to diverse pharmacologically relevant ...
Raúl Martínez‐González +4 more
wiley +1 more source
Studies on the electrochemical reactions of 1-amino phosphonates
Electrochemical direct conversion of 1-aminoalkylphosphonates into novel heteroaromatic compounds has been studied and described. Cyclicvoltametry analysis showed that 1-aminoalkylphosphonate was oxidized in the anode, followed by removing the phosphoryl
Babak Kaboudin +3 more
doaj +1 more source
We introduce uracil–triazole–pyrene peptidomimetics whose tunable peptide linkers precisely control light emission, copper binding, and interactions with DNA and RNA. Fine structural adjustments unlock selective biomolecular recognition and striking metal‐ and membrane‐responsive fluorescence, paving the way for a new generation of multifunctional ...
Dijana Pavlović Saftić +2 more
wiley +1 more source
This review article provides a comprehensive exploration of the synergistic integration of molecular dynamics (MD) simulations and metal–organic frameworks (MOFs) to advance the design and optimization of nanoscale drug delivery systems (DDSs). We believe this work will be of significant interest to researchers in nanomedicine, computational biology ...
Jiahao Xu +11 more
wiley +1 more source
Dual Targeting of DNA and EGFR by ZYH005 Induces DNA Damage and Mitotic Catastrophe in Glioblastoma
ZYH005 exerts potent anti‐glioblastoma activity through a dual mechanism: intercalation‐mediated DNA damage and targeted inhibition of EGFR, leading to cell cycle arrest and mitotic catastrophe. ABSTRACT Glioblastoma multiforme (GBM) is an aggressive, therapy‐resistant brain tumor with limited treatment options.
Jianzheng Huang +12 more
wiley +1 more source
Studies in the phenanthridine series. Part VII. A synthesis of benzo(c)phenanthridine
(Uploaded by Plazi from the Biodiversity Heritage Library) No abstract provided.
openaire +1 more source
A new molecular cocrystal shows D‐A alternative molecular stacking, cyan‐blue photoluminescence with lifetime of 19.76 ns, and two‐photon absorption enabled emission under laser excitation between 720 and 880 nm. Theoretical calculations reveal its static dipole moment of 2.84 D, CT character in the ground, S1, and S2 excited states, and the TPA ...
Weigang Zhu +4 more
wiley +1 more source
Schematic representation depicting the influence of phosphine ligand identity on the biological and physicochemical characteristics of Pt(II) complexes: PTA promotes antileishmanial activity, PPh2(Php–COOH) strengthens antiviral activity, and TCEP enhances fluorescence.
Antonio A. de Oliveira‐Neto +12 more
wiley +1 more source
Studies in the phenanthridine series. Part VI. A synthesis of 3-methyl phenanthridine
(Uploaded by Plazi from the Biodiversity Heritage Library) No abstract provided.
openaire +1 more source

