Results 31 to 40 of about 1,085 (145)

Ir(III) Complexes Convert Cold to Hot Tumors via Ferroptosis/Necroptosis‐Driven Immunogenic Cell Death and Photosensitized CD47 Downregulation

Advanced Science, Volume 13, Issue 8, 9 February 2026.
Red‐light‐activated Ir1 overcomes hypoxia tolerance and adapts to the immunosuppressive tumor microenvironment, converting immunologically cold tumors into inflamed hot microenvironments. This conversion is driven by synergistic induction of immunogenic cell death through coordinated ferroptosis‐necroptosis pathways and spatiotemporally controlled ...
Long‐Bo Yu, Peng Wang, Qing‐Hua Shen, Qi‐Xin Guan, Zhi‐Yuan Li, Ying‐Ying Han, Xin‐Yi Zhang, Qing‐Yuan Hu, Cai‐Ping Tan   +8 more
wiley   +1 more source

Studies in the phenanthridine series. Part IV. 1:10-dimethyl phenanthridines

Journal and proceedings of the Royal Society of New South Wales, 1945
(Uploaded by Plazi from the Biodiversity Heritage Library) No abstract provided.
openaire   +1 more source

A Hypoxia‐Responsive Near‐Infrared Phosphorescence Nanoprobe for High‐Sensitive Detection of Tumor Cells and Imaging of Colorectal Cancer In Situ

Aggregate, Volume 7, Issue 1, January 2026.
We have successfully developed a hypoxia‐responsive near‐infrared phosphorescent probe, Ir‐PEG. This nanoprobe demonstrates high sensitivity, water solubility, and deep‐tissue penetration. It remains specifically activatable even in the hypoxic intestinal environment, facilitating high‐contrast imaging of orthotopic colon cancer.
Jian Chen, Huamin Lan, Sensen Zhou, Weizhi Chen, Xu Zhen, Xiqun Jiang   +5 more
wiley   +1 more source

Dichloridobis(phenanthridine-κN)zinc(II) [PDF]

Acta Crystallographica Section E Structure Reports Online, 2009
In the mol-ecule of the title compound, [ZnCl(2)(C(13)H(9)N)(2)], the Zn(II) atom is four-coordinated in a distorted tetra-hedral configuration by two N atoms from two phenanthridine ligands and by two terminal Cl atoms. The dihedral angle between the planes of the phenanthridine ring systems is 69.92 (3)°.
Khoshtarkib, Zeinab, Ebadi, Amin, Alizadeh, Robabeh, Ahmadi, Roya, Amani, Vahid   +4 more
openaire   +2 more sources

Photo‐Autocatalysis: Insights From Light‐Driven Self‐Catalyzed Organic Transformations

Chemistry – An Asian Journal, Volume 21, Issue 2, 28 January 2026.
This perspective highlights recent advancements in photo‐autocatalytic reactions—light‐driven processes characterized by self‐accelerating kinetics. We explore the underlying mechanisms, demonstrating how photo‐autocatalysis can be realized either through a single photo‐autocatalyst or through a combination of a photocatalyst and an autocatalyst, and ...
James Shao‐Jiun Yang, Aira Shayne Paculba, Hsuan‐Hung Liao   +2 more
wiley   +1 more source

Substitution Kinetics, DNA/BSA Interactions, Cytotoxicity Evaluation and Computational Analysis of [bis‐(azaaryl)amine)Pt(II)/Pd(II)Cl] Complexes, Azaaryl = Quinoline or Phenanthridine

Bioinorganic Chemistry and Applications, Volume 2026, Issue 1, 2026.
The search for metal‐based anticancer agents with improved efficacy and reduced side effects is ongoing. The activities of these anticancer drugs depend on their aqueous stability, substitutional reactivity at target sites (cytotoxicity) and nontarget sites (toxicity), as well as their transportation and cell bioavailability.
Phakamani C. Dlamini, Thato T. Medupe, Lucy W. Macharia, Karabo Serala, Sharon Prince, Gregory S. Smith, Irvin N. Booysen, Allen Mambanda, Franc Perdih   +8 more
wiley   +1 more source

Pathogenic Significance of Trypanosomatids: Progress in Drug Resistance, Control Strategies, and Artificial Intelligence

Interdisciplinary Perspectives on Infectious Diseases, Volume 2026, Issue 1, 2026.
Trypanosomatids, including the genera Trypanosoma and Leishmania, are protozoan parasites of significant medical and veterinary relevance. These organisms cause African trypanosomiasis, Chagas disease, and leishmaniasis, which are classified as neglected tropical diseases (NTDs).
Cynthia Mmalebna Amisigo, Aboagye Kwarteng Dofuor, Jennifer Afua Afrifa Yamoah, Albert Fynn Aiduenu, Blessing Kwabena Gayi, Angelina Akomea, Zenabu Lansah Alidu, Gideon Danso, Selina Mawunyo Ayivi-Tosuh, Naa Kwarley-Aba Quartey, Joseph Harold Nyarko Osei, Seyram Kofi Loh, William Ekloh, Suraiya Saleem   +13 more
wiley   +1 more source

Chinese Herbal Medicines for Diabetic Cardio‐Cerebrovascular Diseases: Key Bioactive Metabolites and Action Mechanisms

Journal of Nutrition and Metabolism, Volume 2026, Issue 1, 2026.
Currently, the global incidence of diabetes is increasing, particularly in populous developing regions. In China, over 290 million people are affected by diabetic cardio‐cerebrovascular diseases. These diseases account for more than 40% of deaths and impose a significant economic burden on both society and families.
Ying Su, Shuwen Luo, Wei Li, Cuicui Cheng, Wei Liu, Xinyu Yang, Zhen Xing, Eric Gumpricht   +7 more
wiley   +1 more source

Rapid Access to Emission‐Tunable Organelle‐Targeted Aggregation‐Induced Emission Luminogens Through One‐Pot Skeletal Editing

Transformative Chemistry, Volume 1, Issue 1, December 2025.
Herein we report a skeletal editing strategy for rapidly transforming readily available isoquinolines into synthetically challenging (dihydrodibenzo[c,i]phenanthridin‐6‐yl)diphenylphosphine oxides (DHBPPO) derivatives. These DHBPPO derivatives exhibit tunable emission, aggregation‐induced emission (AIE) properties, organelle‐targeted specificity, and ...
Yanling Liu, Chaoyang Li, Yunlong Qin, Yifan Cheng, Jianing Zhang, Yang Zhao, Tianhao Wu, Chenghan He, Cheng Xu, Qilin Wang, Zheng Zhao, Ben Zhong Tang   +11 more
wiley   +1 more source

Difluoromethylborates and Muonium for the Study of Isonitrile Insertion Affording Phenanthridines via Imidoyl Radicals. [PDF]

J Org Chem, 2023
Konagaya K, Huang YE, Iwami K, Fujino T, Abe R, Parchment-Morrison R, Kojima KM, McKenzie I, Ito S.   +8 more
europepmc   +1 more source