Iridium-Catalyzed, β-Selective C(sp3)-H Silylation of Aliphatic Amines To Form Silapyrrolidines and 1,2-Amino Alcohols. [PDF]
, 2018 The functionalization of unactivated C(sp3)-H bonds of aliphatic amines catalyzed by transition-metal complexes is important because amine-based functionality is present in a majority of biologically active molecules and commercial pharmaceuticals ...
Hartwig, John F, Lee, Taegyo, Su, Bo
core +3 more sources
Chemistry – A European Journal, EarlyView.ABSTRACT Fluorouracil‐platinum(IV) prodrugs represent a novel class of multimechanistic chemotherapeutics with enhanced anticancer potential. The prodrugs PtIVP‐5FUMeOBut and PtIV56‐5FUMeOBut were actualized by derivatising the clinical drug 5‐fluorouracil (5FU) and coordinating it to platinum(IV) complexes, leveraging the established cytotoxicity of ...
Maria George Elias +9 more
wiley +1 more source
Electron-rich metal phenanthrocyanine – new class of tetraazachromophor complexes of d-elements
Тонкие химические технологии, 2007 Data of experimental and theoretical study (DFT method) of electron-rich metal phenanthrocyanines – new class of tetraazachromophore complexes of delements Pt2+, Pd2+, Rh3+, Cr3+, Co2+, Ni2+, Zn2+ and Cd2+ was presented.
V. N. Demidov +6 more
doaj
Unprecedented comonomer dependence of the stereochemistry control in Pd-catalyzed CO/vinyl arene polyketone synthesis [PDF]
, 2015 Two pyrene-tagged iminopyridines (N-N') were used to synthesize neutral and monocationic, palladium(II) complexes, [Pd(Me)Cl(N-N')] and [Pd(Me)(MeCN)(N-N')][PF6].
Bronco, Simona +7 more
core +3 more sources
Boron Neutron Capture Therapy at a Crossroads: Translational Gap and Emerging Delivery Agents
Chemistry – A European Journal, EarlyView.This review surveys recent advances in boron delivery agents for BNCT, emphasizing the shift from classical small molecules to multifunctional nanocarriers and theranostic systems. By integrating targeting, imaging, and therapy, next‐generation boron compounds aim to bridge the gap between (bio)chemical innovation and clinical translation.
Christoph Selg, Evamarie Hey‐Hawkins
wiley +1 more source
Expedient Discovery of a Metallaphotoredox Cyanomethylation for Synthesizing α‐Aryl Nitriles
Chemistry – A European Journal, EarlyView.A metallaphotoredox cyanomethylation reaction has been developed for the synthesis of valuable α‐aryl nitrile intermediates. The methodology was successfully applied to diverse medicinally‐relevant substrates, providing an expedient route to anti‐cancer Senexin compounds, while also removing the need for toxic cyanide reagents. The mechanism was probed
Gemma C. Cook +6 more
wiley +1 more source
Chemistry – A European Journal, EarlyView.Monosubstituted N‐arylhydroxylamines represent a unique subclass of hydroxylamines that act as pivotal intermediates in redox transformations and as versatile platforms for further synthetic transformations. They serve as key building blocks in the synthesis of architecturally complex heterocycles and other valuable organic compounds.
Michael G. Kallitsakis +2 more
wiley +1 more source
Theoretical and experimental studies of aryl-bithiophene based push-pull pi-conjugated heterocyclic systems bearing cyanoacetic or rhodanine-3-acetic acid acceptors for SHG nonlinear optical applications [PDF]
, 2018 A series of push-pull aryl-bithiophene based systems 2-3 were designed and synthesized in order to understand how structural modifications influence the electronic, linear and nonlinear optical properties. The push-pull conjugated chromophores 2-3 bear a
Belsley, M. +5 more
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Engineered Metal–Organic Frameworks‐Based Materials for Environmental Detection
ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.Engineered metal–organic frameworks (MOFs) regulated by various material modification strategies are discussed for environmental contaminant detection under different sensing mechanisms, providing future improvements of MOFs in environmental detection. Sensitive and selective detection of contaminants is crucial for environmental protection.
Pan Gao +3 more
wiley +1 more source
The versatile SALSAC approach to heteroleptic copper(I) dye assembly in dye-sensitized solar cells [PDF]
, 2018 Surface-bound heteroleptic copper(I) dyes [Cu(L anchor )(L ancillary )] + are assembled using the 'surfaces-as-ligands, surfaces as complexes' (SALSAC) approach by three different procedures. The anchoring and ancillary ligands chosen are ((6,6'-dimethyl-
Constable, Edwin C. +2 more
core +2 more sources