Results in Chemistry, 2023 Phenazines derived from β-lapachone had tuberculostatic activity reported in the literature. However, very little is known about their mechanism of action or molecular targets.
Joyce Sobreiro Francisco Diz de Almeida +1 more
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Genetic regulation of biosynthesis and resistance to redox-active phenazines in Burkholderia spp. [PDF]
Microbiology SpectrumBurkholderia includes gram-negative saprophytes, nitrogen-fixers, and species associated with nosocomial infections. Numerous strains in the Burkholderia cepacia, Burkholderia pseudomallei, Burkholderia glumae, and Burkholderia gladioli clades carry ...
Ankita Bhattacharyya +6 more
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eLife, 2020 Analysis of genetic information from soil samples provides insights into bacteria that help to protect crops from fungal diseases by producing chemicals called phenazines.
Sarah J Wolfson, Libusha Kelly
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Phenazine aus Pseudomonden/Phenazines from Pseudomonads
Zeitschrift Fur Naturforschung - Section B Journal of Chemical Sciences, 1981 Abstract The structure elucidation of several minor phenazine pigments of Pseudomonads is described. 4-Hydroxyphenazine-1,6-dicarboxylic acid dimethyl ester, 2,3-dihydroxyphenazine, 2,3,7-trihydroxyphenazine, 4-hydroxyphenazine-1-carboxylic acid, 2,3-dihydroxyphenazine-1-carboxylic acid, 2,6-dihydroxyphenazine-1-carboxylic acid and 2,3 ...
A Romer
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Bacterial bioactive metabolites can facilitate cooperative interactions within Aspergillus fumigatus–Pseudomonas aeruginosa mixed biofilms by promoting fungal polysaccharide production [PDF]
Applied and Environmental MicrobiologyPathogens are often present alongside other microbial species in chronic infections. The mold Aspergillus fumigatus and bacteria Pseudomonas aeruginosa are both prevalent opportunistic pathogens in cystic fibrosis (CF) patients, and their interactions ...
Qiuchen Li +5 more
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Phenazine-Based Homogeneous Photocatalysts for Visible-Light-Driven Hydrogenation of Nitroarenes Under Mild Conditions [PDF]
MoleculesPhenazine derivatives are promising metal-free chromophores with strong redox and photophysical properties, yet their use in photocatalytic hydrogenation remains limited.
Van Dao +3 more
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Role of Iron Availability in Modulating Pseudomonas aeruginosa’s Antifungal Effects on Planktonic and Biofilm Growth of Scedosporium/Lomentospora Under Cystic Fibrosis-Mimicking Conditions [PDF]
Journal of FungiPseudomonas aeruginosa and Scedosporium/Lomentospora often coexist in the lungs of cystic fibrosis patients, where their interaction can affect disease outcomes. Our group has recently demonstrated that P. aeruginosa suppresses the growth of Scedosporium/
Thaís P. Mello +6 more
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Recent Advances in Phenazine Natural Products: Chemical Structures and Biological Activities [PDF]
MoleculesPhenazine natural products are a class of colored nitrogen-containing heterocycles produced by various microorganisms mainly originating from marine and terrestrial sources. The tricyclic ring molecules show various chemical structures and the decorating
Wei Huang +7 more
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Loss of LasR function leads to decreased repression of Pseudomonas aeruginosa PhoB activity at physiological phosphate concentrations [PDF]
Journal of BacteriologyThe Pseudomonas aeruginosa LasR transcription factor plays a role in quorum sensing (QS) across phylogenetically distinct lineages. However, isolates with loss-of-function mutations in lasR (LasR– strains) are commonly found in diverse settings ...
Amy Conaway +3 more
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Novel Marine Phenazines as Potential Cancer Chemopreventive and Anti-Inflammatory Agents
Marine Drugs, 2012 Two new (1 and 2) and one known phenazine derivative (lavanducyanin, 3) were isolated and identified from the fermentation broth of a marine-derived Streptomyces sp. (strain CNS284). In mammalian cell culture studies, compounds 1, 2 and 3 inhibited TNF-α-
Tamara Kondratyuk +2 more
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