Results 71 to 80 of about 5,571 (181)

Characterization of Tolerance and Cross-tolerance between Noncompetitive N-methyl-D-aspartate (NMDA) Antagonists in Rats Trained to Self-administer Ketamine [PDF]

open access: yes, 1995
Ketamine and phencyclidine (PCP) are noncompetitive antagonists of the N-methyl-D-aspartate (NMDA) type of ligand-gated glutamate receptors. Both agents have high abuse liability, and may produce dependence.
Ward, Amie S. (Amie Sue)
core  

Noncompetitive Functional Inhibition At Diverse Human Nicotinic Acetylcholine Receptor Subtypes By Bupropion Phencyclidine And Ibogaine

open access: yes, 1999
Nicotinic acetylcholine receptors (nAChR) are diverse members of the neurotransmitter-gated ion channel superfamily and play critical roles in chemical signaling throughout the nervous system. The present study establishes the acute functional effects of
Lukas, Ronald J., Fryer, John D.
core  

Mechanism-based inactivation of human cytochrome P450 2B6 by phencyclidine: Metabolism, structural, and mechanistic studies.

open access: yes, 2007
This dissertation presents studies performed to elucidate the structure-function relationships of cytochrome P450 (P450) 2B6, the human 2B homologue responsible for the metabolism of several drugs, carcinogens, and some environmental chemicals ...
Shebley, Mohamad
core  

Exploring the relationship between cold medicine abuse and recreational drug use

open access: yes
Over-the-counter medicines such as cold and cough medications may be abused as an accessible alternative to other recreational drugs in order to obtain a desired ‘high.’ A lack of literature is currently present, with few studies specifically observing ...
Barco, Luis
core   +1 more source

Natural Language Processing for Substance Use Disorder Information Extraction: A Systematic Literature Review. [PDF]

open access: yesCurr Addict Rep
Wyse RJ   +6 more
europepmc   +1 more source

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