Results 131 to 140 of about 78,657 (383)
Sedative Effects of Intraperitoneal Diazepam in Mice
International Journal of Integrated Health Sciences, 2023 Objectives: To determine the effectiveness of Diazepam in comparison with Phenobarbital. Methods: Twenty-seven male Swiss Webster mice were used and randomly divided into three groups of negative control (NS), positive control (Phenobarbital), and ...
Marsha Vania +3 more
doaj
Prophylactic Phenobarbital after Resolution of Neonatal Seizures
Pediatric Neurology Briefs, 2008 The degree of practice variation in continuance of phenobarbital treatment despite resolution of neonatal seizures was evaluated by national survey conducted at the University of Rochester Medical Center, New York.
J Gordon Millichap
doaj +1 more source
Journal of the American Veterinary Medical Association, 2012 OBJECTIVE To compare efficacy and safety of treatment with phenobarbital or bromide as the first-choice antiepileptic drug (AED) in dogs. DESIGN Double-blinded, randomized, parallel, clinical trial.
D. Boothe +2 more
semanticscholar +1 more source
Hepatic microRNA profiles offer predictive and mechanistic insights after exposure to genotoxic and epigenetic hepatocarcinogens. [PDF]
, 2012 In recent years, accumulating evidence supports the importance of microRNAs in liver physiology and disease; however, few studies have examined the involvement of these noncoding genes in chemical hepatocarcinogenesis.
Currie, RA +3 more
core +1 more source
Cubic Phase‐Inducible Zwitterionic Phospholipids Improve the Functional Delivery of mRNA
Advanced Science, EarlyView.In this study, a chemically engineered zwitterionic phospholipids derived from 1,2‐dioleoyl‐3‐sn‐glycero‐phosphoethanolamine (DOPE), DOPE‐Cx, are designed. The DOPE‐Cx lipids induce a cubic phase upon mixing with phosphatidylcholine, facilitate membrane fusion‐mediated endosomal escape, and enhance the functional delivery of mRNA.
Kazuki Iwakawa +5 more
wiley +1 more source
Cancer, Volume 129, Issue 2, Page 215-225, 15 January 2023., 2023 Abstract Background Fatigue is a hallmark of breast cancer and is associated with skeletal muscle deconditioning. If cancer‐related fatigue occurs early during chemotherapy (CT), the development of skeletal muscle deconditioning and its effect on exercise capacity remain unclear. The aim of this study was to investigate the evolution of skeletal muscle
Joris Mallard +9 more
wiley +1 more source
Advanced Science, EarlyView.In this study, a comprehensive single‐cell transcriptome atlas of the Dezhou donkey, encompassing 20 tissues and 275 050 cells, is constructed. Through cross‐species and cross‐tissue analyses, distinct transcriptional patterns in donkey sebocytes are identified.
Yu Tian +11 more
wiley +1 more source
Molecular and cellular paradigms of multidrug resistance in cancer
Cancer Reports, Volume 5, Issue 12, December 2022., 2022 Abstract Background The acquisition of resistance to chemotherapy is a major hurdle in the successful application of cancer therapy. Several anticancer approaches, including chemotherapies, radiotherapy, surgery and targeted therapies are being employed for the treatment of cancer.
Foram U. Vaidya +6 more
wiley +1 more source
Epilepsy & Behavior Reports, 2023 Objectives: Pharmaceutical allergic reactions due to antiseizure medications (ASMs) are one of the major concerns in the management of patients. Finding an alternative ASM which does not cause allergic reactions and has acceptable effectiveness can be ...
Samane Rahimi +6 more
doaj
Advanced Science, EarlyView.These findings reveal that silicon exerts strong protective effects in diabetic bone defect models by selectively promoting Drp1‐Mff activity. Silicon facilitates precise regulation of mitochondrial dynamics to enable functional mitochondrial transfer.
Yu‐Xuan Ma +12 more
wiley +1 more source