Results 191 to 200 of about 63,407 (320)

A Conserved Nuclear Receptor Consensus Sequence (DR-4) Mediates Transcriptional Activation of the Chicken CYP2H1 Gene by Phenobarbital in a Hepatoma Cell Line

, 2000
Christoph Handschin, Urs Meyer
openalex   +1 more source

Bacterial Outer Membrane Vesicles in Potentiating Cancer Vaccines: Progress and Prospects

Advanced Science, EarlyView.
Bacterial outer membrane vesicles (OMVs) have emerged as versatile platforms for cancer vaccine development owing to their intrinsic immunostimulatory properties and high engineering flexibility. This review summarizes OMV biology, immune mechanisms, and engineering strategies that enhance vaccine efficacy, discusses key translational challenges, and ...
Jiabeini Zhang, Tianyu Shao, Fengjiang Qu, Caiyun Bai, Sijie Li, Pin Gao, Wenna Li, Keman Cheng, Xiao Zhao, Zhimin Fan   +9 more
wiley   +1 more source

Efficacy of Levetiracetam Use in Neonatal Seizure: A Retrospective Cohort Study. [PDF]

NeuroSci
Alsehli FA, Alghamdi J, Homedi A, Alsaif S, Ali K, Alzahrani WS, Albekairy NA, Obaidat AA, Shawaqfeh MS, Alawad BA, Alfulaij AA, Almamoon NM, Albekairy AM.   +12 more
europepmc   +1 more source

Excretion of organic acids associated with biotin deficiency in chronic anticonvulsant therapy [PDF]

, 1984
Berlit, Peter, Bonjour, Jean-Pierre, Kochen, W., Krause, Klaus-Henning   +3 more
core  

Effect of phenobarbital and 3-methylcholanthrene on decrease in pH in liver induced by 3'-methyl-4-dimethylaminoazobenzene, of partial hepatectomy and hepatotoxic agents.

, 1979
Yoko Kitagawa, Yukio Kuroiwa
openalex   +2 more sources

333 REVERSAL OF PHENOBARBITAL (PB) INDUCED ALTERATION IN SEXUAL DIFFERENTIATION BY CYCLOHEXIMIDE AND HYDROXY UREA [PDF]

, 1981
Chhanda Gupta, Sumner J. Yaffe
openalex   +1 more source

Promoter Hypermethylation‐Induced Silencing of FXYD1 Drives Breast Cancer Metastasis via DDX5‐Mediated Wnt/β‐Catenin Pathway Activation

Advanced Science, EarlyView.
This study identifies FXYD1 as an epigenetically silenced tumor suppressor in breast cancer. DNA methylation turns off the gene FXYD1 in breast cancer, and low levels predict worse outcomes. Restoring FXYD1 limits breast cancer cells proliferation and metastasis. In the nucleus, FXYD1 recruits the E3 ligase MAEA to K63‐ubiquitinate DDX5 for proteasomal
Ping Wen, Fanli Qu, Long Wang, Qing Shao, Sisi Li, Yang Qin, Dongping Jiang, Senmiao Zhang, Jiangdong Sui, Guanwen Wang, Ningning Zhang, Xiaohua Zeng   +11 more
wiley   +1 more source

Treatment considerations for the management of neonatal onset seizures. [PDF]

J Pediatr Pharmacol Ther
Burdine J, Capino A, Harlow M, Mitchell-Vansteele A, Cokley J.   +4 more
europepmc   +1 more source

Resistance to Phenobarbital Extends to Phenytoin in a Rat Model of Temporal Lobe Epilepsy [PDF]

, 2007
Kerstin Bethmann, Claudia Brandt, Wolfgang Löscher   +2 more
openalex   +1 more source

Leveraging Artificial Intelligence and Large Language Models for Cancer Immunotherapy

Advanced Science, EarlyView.
Cancer immunotherapy faces challenges in predicting treatment responses and understanding resistance mechanisms. Artificial intelligence (AI) and machine learning (ML) offer powerful solutions for cancer immunotherapy in patient stratification, biomarker discovery, treatment strategy optimization, and foundation model development.
Xinchao Wu, Mengtao Sun, Lusheng Li, Jieqiong Wang, Shibiao Wan   +4 more
wiley   +1 more source