Results 281 to 290 of about 78,657 (383)

Effects of perampanel on bone health in adult patients with epilepsy

open access: yesEpilepsia Open, EarlyView.
Abstract Objective The objective was to assess the effects of perampanel (PER) on bone metabolism and bone mineral density (BMD) in adult patients with epilepsy. Methods This retrospective study included consecutive patients admitted to the Epilepsy Center of Sichuan Provincial People's Hospital from January 2023 to June 2024.
Mingxing Yu   +8 more
wiley   +1 more source

Therapeutic Options for Crigler-Najjar Syndrome: A Scoping Review. [PDF]

open access: yesInt J Mol Sci
Sambati V   +3 more
europepmc   +1 more source

Engineered brain‐targeting exosome for reprogramming immunosuppressive microenvironment of glioblastoma

open access: yesExploration, EarlyView.
An acid‐cleavable Tf‐modified engineering exosome‐based brain‐targeting delivery system (ACTE) was proposed using metabolic glycoengineering and bioorthogonal click chemistry, enabling co‐delivery of siTGF‐β and DOX for GBM treatment. ACTE was featured by higher BBB transcytosis efficiency and hierarchical targeting delivery to GBM cells.
Jun Yang   +14 more
wiley   +1 more source

Riding a Vascular Time Train to Spatiotemporally Attenuate Thrombosis and Restenosis by Double Presentation of Therapeutic Gas and Biomacromolecules

open access: yesExploration, EarlyView.
This project develops a biomimetic stent coating with a double presentation of therapeutic biomacromolecule VEGF and therapeutic gas NO, which spatiotemporally promotes vessel repair including promoting rapid re‐endothelialization, effectively preventing thrombosis, suppressing inflammation and restenosis.
Jingdong Rao   +10 more
wiley   +1 more source

Berries: Health Effects via Modulation of the Gut Microbiota

open access: yesFood Frontiers, EarlyView.
ABSTRACT Berries are widely regarded as beneficial foods, rich in polyphenols, flavonoids, and other bioactive compounds that could positively influence human health. Although the gut microbiota plays a crucial role in metabolism and physiology of humans, the interaction between berries and human gut microbiota activity remains unclear.
Manjin Xu   +11 more
wiley   +1 more source

Organ‐on‐Chip: The Future of Nutrition Research in a One Health World

open access: yesFood Frontiers, EarlyView.
Organ‐on‐chips offer a promising tool for evaluating food and feed safety. Organ‐on‐chips also present a scientifically robust and ethical alternative to animal studies. ABSTRACT The One Health approach emphasizes the interconnectedness of human, animal, and environmental health, recognizing that the health of each is interdependent and influenced by ...
Manuela Cassotta   +8 more
wiley   +1 more source

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