Results 291 to 300 of about 78,657 (383)

The Alzheimer's Disease Gene SORL1 Regulates Lysosome Function in Human Microglia

Glia, EarlyView.
ABSTRACT The SORL1 gene encodes the sortilin‐related receptor protein SORLA, a sorting receptor that regulates endo‐lysosomal trafficking of various substrates. Loss of function variants in SORL1 are causative for Alzheimer's disease (AD) and decreased expression of SORLA has been repeatedly observed in human AD brains. SORL1 is highly expressed in the
Swati Mishra, Nader Morshed, Sonia Beant Sidhu, Chizuru Kinoshita, Beth Stevens, Suman Jayadev, Jessica E. Young   +6 more
wiley   +1 more source

Optimal Drug, Optimal Dose, or Both in the Pharmacological Treatment of Neonatal Opioid Withdrawal Syndrome? [PDF]

Clin Pharmacol Ther
Kraft WK.
europepmc   +1 more source

Decompensated MASH-Cirrhosis Model by Acute and Toxic Effects of Phenobarbital. [PDF]

Cells
Kraus N, Uschner FE, Moeslein M, Schierwagen R, Gu W, Brol MJ, Fürst E, Grünewald I, Lotersztajn S, Rautou PE, Duran-Güell M, Flores Costa R, Clària J, Trebicka J, Klein S, DECISION.   +15 more
europepmc   +1 more source

Acute Liver Injury by Vinyl Chloride: Involvement of Endoplasmic Reticulum in Phenobarbital-Pretreated Rats

, 1975
Edward S. Reynolds, Rudolph J. Jaeger, Sheldon D. Murphy   +2 more
openalex   +1 more source

A Case of Neonatal Cytotoxic Lesions of the Corpus Callosum With Subpial Hemorrhage. [PDF]

Cureus
Ban Y, Tagawa H, Wakatsuki K, Onishi R, Noda T, Sugawara M, Ando K.   +6 more
europepmc   +1 more source

Separation and purification of multiple forms of microsomal cytochrome P-450. Partial characterization of three apparently homogeneous cytochromes P-450 prepared from livers of phenobarbital- and 3-methylcholanthrene-treated rats

, 1978
F. Peter Guengerich
openalex   +1 more source

Teratogenicity Rates in Nearly 10 000 Offsprings of Antiseizure Medication-Exposed Pregnancies. [PDF]

Epilepsy Curr
Kobayashi E.
europepmc   +1 more source

Response to amoxicillin and perampanel in infantile Alexander disease. [PDF]

Epilepsia Open
Boronat S, Turon-Viñas E, Mac Manus N, Diaz-Gomez A, Vicente M, Ros-Castelló V, Sierra-Marcos A.   +6 more
europepmc   +1 more source

Thromboelastography in dogs with idiopathic epilepsy treated with phenobarbital monotherapy. [PDF]

Vet Clin Pathol
García R, Pastor J, de la Fuente C, Añor S.   +3 more
europepmc   +1 more source

Research progress of neurovascular units involved in ischemic stroke

Ibrain, EarlyView.
The brain receives less blood when an ischemic stroke develops, which damages neurons and leads to an increased release of Pro‐inflammatory mediators that activate neurovascular unit (NVU). When the tight junctions are broken and the basement membrane is disrupted by matrix metalloproteinases produced by active endothelial and pericellular cells ...
Yu Yang, Hao Tong, Zhuo‐Fan Ye, Zu‐Cai Xu, Tao Tao   +4 more
wiley   +1 more source