Results 301 to 310 of about 86,047 (385)

Porin‐Independent Uptake of Small Molecule Antibiotics Facilitated by Escherichia coli Outer Membrane Vesicles

open access: yesBiotechnology and Bioengineering, EarlyView.
We demonstrate that bacterial outer membrane vesicles (OMVs) can enhance antibiotic delivery into Gram‐negative bacteria by bypassing porin‐dependent uptake. Encapsulation of imipenem in OMVs significantly increased its effectiveness against multidrug‐resistant clinical isolates, highlighting OMVs as a promising platform for overcoming permeability ...
Meishan Wu   +3 more
wiley   +1 more source

Proteomic and Ubiquitinated Proteome Insights Into ER Stress Responses in Chinese Hamster Ovary Cells Under Mild Hypothermic Conditions

open access: yesBiotechnology and Bioengineering, EarlyView.
Proteomic analysis of CHO cells under mild hypothermia (31°C) reveals ER stress responses, ubiquitination dynamics, and adaptive mechanisms. Magnetic immuno‐affinity enrichment and mass spectrometry highlight protein regulation differences in non‐producer versus producer cells, offering insights for optimising biopharmaceutical production of IgG1 and ...
David Ryan   +5 more
wiley   +1 more source

The Development of the Human Female Reproductive Tract. Part 1: Uterine Tube and Uterus

open access: yesClinical Anatomy, EarlyView.
ABSTRACT The uterine tubes and uterus develop from the paramesonephric (Müllerian) ducts. Most experimental data are obtained in rodents. Since the (micro‐)anatomy of the murine urogenital tract differs from that in humans, evaluation of the translatability of mouse data to human development is relevant.
Cindy J. M. Hülsman   +4 more
wiley   +1 more source

Processing of mitochondrial precursor proteins [PDF]

open access: yes, 1984
Neupert, Walter, Schmidt, Bernd
core  

The Development of the Human Female Reproductive Tract: Part 2—Vagina

open access: yesClinical Anatomy, EarlyView.
ABSTRACT Urogenital epithelium replaces the original paramesonephric (Müllerian) epithelium in the human fetal vagina. We re‐investigated this cell replacement histologically and with three‐dimensional reconstructions. In the lesser pelvis, both Müllerian ducts fuse to form the uterovaginal canal.
Cindy J. M. Hülsman   +4 more
wiley   +1 more source

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