Results 91 to 100 of about 1,375,072 (318)

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

open access: yesMolecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou   +12 more
wiley   +1 more source

Figurative text phenomena and text metaphtonymy [PDF]

open access: yes, 2014
In this paper, I present four figurative text phenomena, figurative schemes which play a role in organizing language at the level of the whole text, either by patterning lexis or changing register. These phenomena have all been identified individually by
Denroche, C.
core  

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Identification and separation of two concurrent partial discharge phenomena [PDF]

open access: yes, 1996
The problem of identification and separation of two Partial Discharge (PD) phenomena simultaneously active has been investigated. Combined PD phenomena, caused by different PD mechanisms, are separated by means of a stochastic procedure based on the ...
Cacciari M.   +3 more
core  

Qualitative Developmental Research Methods in their Historical and Epistemological Contexts

open access: yesForum: Qualitative Social Research, 2006
Methodology is not a "toolbox" of different methods from which the researcher selects some on the basis of personal or social preferences. If the Ganzheitspsychologie traditions of the last century have taught us anything, then it is the importance for ...
Rainer Diriwächter, Jaan Valsiner
doaj  

The influence of irrigated agriculture, urbanisation and water scarcity on human-water system dynamics

open access: yesFrontiers in Water
Large dams have become a dominant water management strategy over the last century, but they are typically managed with limited understanding of how human responses to their construction and operation influence the achievement of water management ...
Imogen Frawley   +5 more
doaj   +1 more source

The idea of religious conflicts as a clash of epistemologies [PDF]

open access: yesKom: Časopis za Religijske Nauke, 2018
This paper will show the following: the distinctions among belief, religious belief, religion, and theology as religious instruction in belief; an explication of the concept of religious conflicts; the (im)possibility of realizing the ideals of ...
Grbić Safer
doaj  

Gate controlled anomalous phase shift in Al/InAs Josephson junctions

open access: yesNature Communications, 2020
The anomalous Josephson effect can be regarded as the hall-mark effect of superconducting spintronics. Here, the authors report the observation of a tunable anomalous Josephson effect in InAs/Al Josephson junctions measured via a superconducting quantum ...
William Mayer   +5 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Physico-chemical phenomena in thin films and at solid surfaces. [PDF]

open access: yes, 2007
The book is devoted to the consideration of the different processes taking place in thin films and at surfaces. Since the most important physico-chemical phenomena in such media are accompanied by the rearrangement of an intra- and intermolecular ...
Lin, S. H.(Sheng Hsien),   +2 more
core  

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