Results 91 to 100 of about 3,745,370 (303)

Topics in coarsening phenomena

These lecture notes give a very short introduction to coarsening phenomena and summarize some recent results in the field. They focus on three aspects: the super-universality hypothesis, the geometry of growing structures, and coarsening in the spiral ...
Al Hammal, Allen, Arenzon, Aron, Barkema, Barros, Biroli, Bray, Bray, Cardy, Chayes, Corberi, Dalmas, Fisher, Fortuin, Gambassi, Gardiner, Goldenfeld, Grimmet, Henkel, Hinrichsen, Huse, Huse, Iguain, Jacobsen, Janke, Janssen, Jäckle, Kandel, Leonard, Leticia F. Cugliandolo, Lifshitz, Miller, Picco, Pitts, Puri, Rao, Reiter, Rieger, Risken, Saleur, Schmittmann, Sellitto, Sicilia, Sicilia, Sicilia, Sicilia, Sollich, Stauffer, Stavans, Toninelli, Toninelli, Toninelli, Täuber, Vanderzande, von Neumann, Vázquez, Wagner, Wu   +58 more
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USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Critical Phenomena in DIS

Saturation in deep inelastic scattering (DIS) and deeply virtual Compton scattering (DVCS) is associated with a phase transition between the partonic gas, typical of moderate $x$ and $Q^2$, and partonic fluid appearing at increasing $Q^2$ and decreasing ...
Jenkovszky, L. L., Nagy, Andrea, Troshin, S. M., Turoci, Jolan, Tyurin, N. E.   +4 more
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A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Entropy-driven cutoff phenomena

In this paper we present, in the context of Diaconis' paradigm, a general method to detect the cutoff phenomenon. We use this method to prove cutoff in a variety of models, some already known and others not yet appeared in literature, including a chain ...
Benedetto Scoppola, Carlo Lancia, D. Aldous, D. Bayer, D.A. Levin, D.A. Levin, E. Presutti, Francesca R. Nardi, J. Barrera, J. Ding, M. Jerrum, P. Diaconis, P. Diaconis, P. Diaconis, P. Erdős, S. Martinez, W. Feller, W. Feller   +17 more
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A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Novel QCD Phenomena [PDF]

I discuss a number of novel topics in QCD, including the use of the AdS/CFT correspondence between Anti-de Sitter space and conformal gauge theories to obtain an analytically tractable approximation to QCD in the regime where the QCD coupling is large ...
Brodsky, Stanley J.
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Entropy Distance: New Quantum Phenomena [PDF]

We study a curve of Gibbsian families of complex 3x3-matrices and point out new features, absent in commutative finite-dimensional algebras: a discontinuous maximum-entropy inference, a discontinuous entropy distance and non-exposed faces of the mean ...
Amari S., Andreas Knauf, Ay N., Barndorff-Nielsen O., Caticha A., Ellis R., Kojima M., Matúš F., Petz D., Stephan Weis, Weis S., Weis S.   +11 more
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Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Lean Limit Phenomena [PDF]

The influence of stretch and preferential diffusion on premixed flame extinction and stability was investigated via two model flame configurations, namely the stagnation flame and the bunsen flame.
Law, C. K.
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