Results 101 to 110 of about 1,375,072 (318)
Series: Practical guidance to qualitative research. Part 1: Introduction
European Journal of General Practice, 2017 In the course of our supervisory work over the years, we have noticed that qualitative research tends to evoke a lot of questions and worries, so-called Frequently Asked Questions.
Albine Moser, Irene Korstjens
doaj +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Analysis of Flow Instabilities on a Three-Bladed Axial Inducer in the Fixed and Rotating Frames [PDF]
, 2017 The paper describes the results of an experimental campaign performed on a three bladed axial inducer with tapered hub and variable pitch, named RAPDUD. The tests have been performed at the Cavitating Pump Rotordynamic Test Facility at Sitael.
Valentini D. +4 more
core
International Journal of Applied Mechanics and EngineeringThe work's goal is to learn more about how a magnetic field, Brownian motion, and thermophoresis diffusion influence convective heat transfer in a micropolar-nanofluid flow's laminar boundary layer.
Najib Mohamed Bouaziz +3 more
doaj +1 more source
Astrocyte heterogeneity in brain metastases
Molecular Oncology, EarlyView.Astrocytes emerge as pivotal regulators of metastatic colonization, survival, immune remodeling, and therapy response associated with an increasing heterogeneity that requires spatially and longitudinally resolved approaches to uncover regulatory programs and guide context‐specific therapies.
Carolina Hernández‐Oliver +2 more
wiley +1 more source
Translating whole‐genome doubling into precision medicine in cancer
Molecular Oncology, EarlyView.Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
Significance of the microfluidic concepts for the improvement of macroscopic models of transport phenomena [PDF]
, 2011 This paper was presented at the 3rd Micro and Nano Flows Conference (MNF2011), which was held at the Makedonia Palace Hotel, Thessaloniki in Greece.
Krol, M +1 more
core
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Molecular Oncology, EarlyView.Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant +11 more
wiley +1 more source
Nonlinear Dynamic Phenomena in Mechanics [PDF]
, 2011 Nonlinear phenomena should play a crucial role in the design and control of engineering systems and structures as they can drastically change the prevailing dynamical responses.
Jerzy Warminski +4 more
core