Results 51 to 60 of about 1,684,514 (304)

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Some applications of linear response theory to media with mechanical relaxation phenomena

open access: yes, 2007
The general linear response theory it applied for study mechanical relaxations phenomena in continuous media. It is shown that phenomenological and state coefficients, in viscoanelastic media can be obtained as function of quantities which are ...
Ciancio V., Farsaci F., Ciancio A.
core   +1 more source

Missing Shapiro steps in topologically trivial Josephson junction on InAs quantum well

open access: yesNature Communications, 2021
Recent observations of missing odd Shapiro steps have been interpreted in the context of topological superconductivity. Here, the authors observe missing odd Shapiro steps in topologically trivial Josephson junctions due to high transparency of the ...
Matthieu C. Dartiailh   +7 more
doaj   +1 more source

Simulation of steady-state and transient loss of cooling accident of a channel in a reactor plate-type fuel element

open access: yesBrazilian Journal of Radiation Sciences, 2023
The suitable cooling of fuel elements in a nuclear reactor is an important requirement that must be met to avoid that the fuel temperature rises above the safety limits according to the reactor design.
D. B. Monteiro, J. R. Maiorino
doaj   +1 more source

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

The voice of the florist. A message about we-ness awareness

open access: yesMurmurations, 2022
As a systemic therapist, I have found Karen Barad’s physics-philosophy useful when trying to comprehend understandings of my responses from within the ongoing stream of my interactions with clients.
Joanna Michopoulou
doaj   +1 more source

Reconstituting Phenomena [PDF]

open access: yes, 2015
In the face of causal complexity, scientists reconstitute phenomena in order to arrive at a more simplified and partial picture that ignores most of the “bigger picture.” This paper will distinguish between two modes of reconstituting phenomena: one moving down to a level of greater decomposition (toward organizational parts of the original phenomenon),
Kronfeldner, Maria   +4 more
openaire   +3 more sources

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

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