Results 131 to 140 of about 18,717 (242)

CD8 T Cell Sensing of Type I Interferon Impacts Anergy

European Journal of Immunology, Volume 56, Issue 5, May 2026.
Basal IFN‐I acts as a rheostat to fine‐tune CD8 T cell anergy. The presence of IFN‐I induces a less deep anergic state characterised by greater expansion, residual effector function and plasticity. This favours the accumulation of autoreactive T cells that retain the potential to break tolerance rather than undergoing deletion.
Anne S. Haefke, Hanna Gröber, Ioana Sandu, Vanessa Skipness, Nikos Pantouloufos, Fabienne Gräbnitz, Marie‐Elen Tuchel, Nathan Zangger, Dominique Stark, Marvin Kříž, Carmine Cristinzio, Hanspeter Pircher, Roman Spörri, Isaak Quast, Annette Oxenius   +14 more
wiley   +1 more source

Introgression of a Terminal Segment From Chromosome 3S of Festuca mairei Increases Drought Resistance of Lolium perenne

Food and Energy Security, Volume 15, Issue 3, May/June 2026.
ABSTRACT Due to climate change, the requirement for increased resilience by grassland systems to onsets of ever‐increasing drought stresses makes the development of drought‐resistant forage crops a priority for future food and energy security. Novel ×Festulolium (Festuca × Lolium) cultivars offer unique opportunities to combine complementary traits ...
David Kopecký, Vladimír Černoch, Martin Duchoslav, Mike W. Humphreys   +3 more
wiley   +1 more source

A Systematic Review to Summarize and Critically Appraise Existing Phenotype Libraries Using Electronic Health Records

Pharmacoepidemiology and Drug Safety, Volume 35, Issue 5, May 2026.
ABSTRACT Purpose Pharmacoepidemiology and population health studies using electronic health care records (EHRs) must define study variables through available electronic data. These variables are operationalized through phenotypes, which are a defined set of criteria used to identify specific traits or medical conditions.
Sima Mohammadi, Cori Campbell, Miriam C. J. M. Sturkenboom, Tiago A. Vaz   +3 more
wiley   +1 more source

Thiol post‐translational modifications modulate allosteric regulation of the OpcA–G6PDH complex through conformational gate control

Protein Science, Volume 35, Issue 5, May 2026.
Abstract In cyanobacteria, the redox‐sensitive protein OpcA acts as a metabolic switch for G6PDH, enabling rapid adjustment of reducing power generation from glycogen catabolism and thereby precisely regulating carbon flux between anabolic and catabolic pathways.
Hoshin Kim, Song Feng, Pavlo Bohutskyi, Xiaolu Li, Daniel Mejia‐Rodriguez, Tong Zhang, Wei‐Jun Qian, Margaret S. Cheung   +7 more
wiley   +1 more source

Influence of Sex and Diagnosis on Clinical Variables and Neurocognitive Performance in Severe Mental Illness. Results From the PsyCourse Study

Acta Psychiatrica Scandinavica, Volume 153, Issue 5, Page 449-467, May 2026.
ABSTRACT Introduction Bipolar disorder (BD) and schizophrenia (SZ) are serious mental illnesses (SMI) with overlapping symptoms but distinct differences in onset and course. Sex differences are an area of growing interest in SMI. This study aims to examine potential interactions between sex and diagnosis across a broad range of variables, to compare ...
Maria Serra‐Navarro, Maria Heilbronner, Brisa Solé, Roger Borràs, Anabel Martinez‐Arán, Kristina Adorjan, Alba Navarro‐Flores, Mojtaba Oraki Kohshour, Daniela Reich‐Erkelenz, Eva C. Schulte, Fanny Senner, Ion‐George Anghelescu, Volker Arolt, Bernhard T. Baune, Udo Dannlowski, Detlef E. Dietrich, Andreas J. Fallgatter, Christian Figge, Markus Jäger, Georg Juckel, Carsten Konrad, Jens Reimer, Eva Z. Reininghaus, Max Schmauß, Andrea Schmitt, Carsten Spitzer, Jens Wiltfang, Jörg Zimmermann, Sergi Papiol, Urs Heilbronner, Peter Falkai, Thomas G. Schulze, Eduard Vieta, Carla Torrent, Monika Budde, Silvia Amoretti   +35 more
wiley   +1 more source

Use of Phenomics in the Selection of UAV-Based Vegetation Indices and Prediction of Agronomic Traits in Soybean Subjected to Flooding

AgriEngineering
Flooding is a frequent environmental stress that reduces soybean growth and grain yield in many producing areas in the world, such as the United States, Southeast Asia, and Southern Brazil.
Charleston dos Santos Lima, Darci Francisco Uhry Junior, Ivan Ricardo Carvalho, Christian Bredemeier   +3 more
doaj   +1 more source

phenome

Citation: 'phenome' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.15977 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +1 more source

Spectral Characterization of the Life Stages and Physiological Responses of Diatraea saccharalis Fabricius (Lepidoptera: Crambidae) Larvae Parasitized by Cotesia flavipes Cameron (Hymenoptera: Braconidae)

Entomologia Experimentalis et Applicata, Volume 174, Issue 5, Page 436-452, May 2026.
Hyperspectral proximal sensing was used to characterize the life stages and physiological responses of Diatraea saccharalis and to detect parasitism by Cotesia flavipes. Distinct spectral signatures differentiated eggs, larval instars, pupae, and adults, as well as live, dead, and parasitized larvae.
Souradji I. Bachirou, David L. Rosalen, Sergio A. De Bortoli, Pedro G. Peixoto   +3 more
wiley   +1 more source

Stem microanatomical phenomic uncovers a potential role for ZmLSM2 in regulating maize stem bending strength

Journal of Integrative Plant Biology, Volume 68, Issue 5, Page 1271-1289, May 2026.
Maize ZmLSM2 (U6 small nuclear ribonucleoprotein specific Sm‐like 2) controls maize stem strength by affecting vascular bundle structure. Using advanced computed tomography imaging and artificial intelligence identified key stem traits linked to lodging resistance and developed a predictive model.
Ying Zhang, Zejia Wang, Jianjun Du, Jiawen Li, Guanmin Huang, Yanxin Zhao, Yanru Wang, Qingmei Men, Minkun Guo, Minggang Zhang, Xianju Lu, Chuanyu Wang, Qikun Liu, Xinyu Guo, Chunjiang Zhao   +14 more
wiley   +1 more source

Phenomes

Improvements in genomic technologies have outpaced the most optimistic predictions, allowing industry-scale application of genomic selection. However, only marginal gains in genetic prediction accuracy can now be expected by increasing marker density up to sequence, unless causative mutations are identified.
Perez-Enciso, Miguel||, Steibel, Juan P.
openaire   +1 more source