Results 81 to 90 of about 22,216 (274)

Sodium butyrate ameliorates renal tubular lipid accumulation through a protein phosphatase 2A/transcription factor EB axis in diabetic nephropathy

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Extensive evidence indicates that lipid accumulation causes renal tubular injury, which further contributes to diabetic nephropathy (DN) progression. Short‐chain fatty acids (SCFAs) play an important role in the maintenance of cellular metabolic health.
Jiayin Tao   +12 more
wiley   +1 more source

The pharmacist’s response to the needs of patients undergoing treatment with psychotropic medication [PDF]

open access: yes, 1999
The usage of psychotropic (Table 1) medication is considerable world wide. In Malta, this can be attested to by the numerous studies that have been conducted by the University of Malta Department of Pharmacy (in conjuction with other institutions and ...
Sant Fournier, Mary Ann
core  

Efficient synthesis of benzothiazine and acrylamide compounds [PDF]

open access: yes, 2010
This article describes the synthesis of the new (2Z)-2-(4-methoxybenzylidene)-6-nitro-4H -benzo[1,4]thiazin-3-one, (2Z)-2-(4-methoxybenzylidene)-4-methyl-6-nitro-4H-benzo[1,4]thiazin-3-one, (2Z)-6-amino-2-(4-methoxybenzylidene)-4H -benzo[1,4]thiazin-3 ...
BARBOSA FILHO, José Maria   +8 more
core   +2 more sources

When Delirium Unmasks a Silent Myocardial Infarction

open access: yesJournal of the American Geriatrics Society, EarlyView.
Abbreviations: hs‐TnT: high sensitivity Troponin T; STEMI: ST‐elevation myocardial infarction.
Eugenia Casali   +10 more
wiley   +1 more source

Effects of typical and atypical antipsychotic drugs on gene expression profiles in the liver of schizophrenia subjects

open access: yesBMC Psychiatry, 2009
Background Although much progress has been made on antipsychotic drug development, precise mechanisms behind the action of typical and atypical antipsychotics are poorly understood.
Song Jonathan   +7 more
doaj   +1 more source

Update on medication-overuse headache and its treatment [PDF]

open access: yes, 2015
OPINION STATEMENT: Medication-overuse headache-i.e., a too-frequent consumption of acute headache medications leading to increased headache frequency and reduced effectiveness of acute and preventive treatments-is a serious medical condition whose ...
Giamberardino MA   +2 more
core   +1 more source

Photodynamic inactivation increases cell death rate on persistent Staphylococcus aureus

open access: yesPhotochemistry and Photobiology, EarlyView.
Persistent bacteria have the ability to survive extended periods of antibiotic stress by entering a metabolically dormant state. This study investigated persistence formation in two S. aureus strains and evaluated the effects of PDI using curcumin. Post‐PDI time‐kill assays conducted after metabolic recovery showed a higher rate of bacterial death ...
Maria Vitória Silva Pereira   +3 more
wiley   +1 more source

Identification of phenothiazine derivatives as UHM-binding inhibitors of early spliceosome assembly

open access: yesNature Communications, 2020
So far only a few compounds have been reported as splicing modulators. Here, the authors combine high-throughput screening, chemical synthesis, NMR, X-ray crystallography with functional studies and develop phenothiazines as inhibitors for the U2AF ...
Pravin Kumar Ankush Jagtap   +14 more
doaj   +1 more source

Role of antimicrobial photodynamic therapy (aPDT) and systemic resveratrol on immediate implant placement in type 2 diabetic rats

open access: yesPhotochemistry and Photobiology, EarlyView.
This study evaluated the combined effects of antimicrobial photodynamic therapy (aPDT) and systemic resveratrol on bone repair around immediately placed implants in type 2 diabetic rats. Resveratrol improved glycemic control and body weight, while aPDT increased implant stability and bone mineralization.
Letícia Pitol‐Palin   +8 more
wiley   +1 more source

Computer Library Literature Review on Effectiveness of Antimotion Sickness Drugs [PDF]

open access: yes
Physiological responses to antimotion sickness drugs - antihistamines, belladonnas, and ...
Graybiel, A.   +4 more
core   +1 more source

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