Results 211 to 220 of about 3,800,975 (380)

Is the clinical malignant phenotype of prostate cancer a result of a highly proliferative immune‐evasive B7‐H3‐expressing cell population? [PDF]

, 2012
Yishan Liu, Ljiljana Vlatkovic, Thorstein Sæter, Einar Servoll, Gudmund Waaler, Jahn M. Nesland, Karl‐Erik Giercksky, Karol Axcrona   +7 more
openalex   +1 more source

Redox regulation meets metabolism: targeting PRDX2 to prevent hepatocellular carcinoma

Molecular Oncology, EarlyView.
PRDX2 acts as a central redox hub linking metabolic dysfunction‐associated steatohepatitis (MASH) to hepatocellular carcinoma (HCC). In normal hepatocytes, PRDX2 maintains redox balance and metabolic homeostasis under oxidative stress. In contrast, during malignant transformation, PRDX2 promotes oncogenic signaling, stemness, and tumor initiation ...
Naroa Goikoetxea‐Usandizaga, María Luz Martinez‐Chantar, Carolina Conter   +2 more
wiley   +1 more source

Grand Challenges to Livestock Physiology and Management

Frontiers in Animal Science, 2021
Geoffrey E. Dahl, Erin E. Connor
doaj   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Resting-State Functional Connectivity of the Central Executive Network Moderates the Relationship Between Neighborhood Violence and Proinflammatory Phenotype in Children

, 2021
Gregory E. Miller, Edith Chen, Eric D. Finegood, Phoebe H. Lam, Rachel Weissman-Tsukamoto, Adam K.K. Leigh, Lauren Hoffer, Ann Carroll, Gene H. Brody, Todd B. Parrish, Robin Nusslock   +10 more
openalex   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Clinical Soft Tissue Adaptation to Biomechanical Modulation with the Bone Protection System (BPS): A Two-Case Report in Thin-Biotype Patients. [PDF]

J Clin Med
Kuc AE, Kotuła J, Sybilski K, Hajduk G, Lis J, Kawala B, Sarul M, Sulewska M.   +7 more
europepmc   +1 more source

Growth Factor Regulation of Corneal Keratocyte Mechanical Phenotypes in 3-D Collagen Matrices

, 2012
Neema Lakshman, W. Matthew Petroll
openalex   +2 more sources

Transcriptional response of human articular chondrocytes treated with fibronectin fragments: an in vitro model of the osteoarthritis phenotype

, 2020
Kathleen S Metz Reed, Veronica Ulici, James Kim, Susan Chubinskaya, Richard F. Loeser, Douglas H. Phanstiel   +5 more
openalex   +2 more sources