Results 261 to 270 of about 2,545,958 (345)

Regulation of mitochondrial membrane assembly in Neurospora crassa. Transient expression of a respiratory mutant phenotype.

, 1975
J Klein, David L. Edwards, Sigurd Werner
openalex   +1 more source

Human Mesenchymal Stem Cells Differentiate to a Cardiomyocyte Phenotype in the Adult Murine Heart

Circulation, 2002
C. Toma, M. Pittenger, K. Cahill, B. Byrne, P. Kessler   +4 more
semanticscholar   +1 more source

Exploring if Longitudinal Changes on PET Imaging Can Serve as a Biomarker for Stiff Person Syndrome Spectrum Disorders

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To identify metabolic patterns in the brain and musculoskeletal system of stiff person syndrome spectrum disorders (SPSD) patients over time using PET imaging and evaluate the impact of immune therapy on metabolic activity as a surrogate for treatment response.
Munther M. Queisi, Samantha N. Roman, Mohammad S. Sadaghiani, Lilja B. Solnes, Scott D. Newsome   +4 more
wiley   +1 more source

Reverse control of biological networks to restore phenotype landscapes. [PDF]

Sci Adv
Jung I, Hopper C, Jang SH, Yeo H, Cho KH.   +4 more
europepmc   +1 more source

NOTCH2NLC Repeat Expansions in Parkinsonian Disorders: Clinical and Neuroimaging Characteristics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neuronal intranuclear inclusion disease (NIID) is a neurodegenerative disorder caused by NOTCH2NLC GGC repeat expansions, with heterogeneous clinical manifestations, including parkinsonism. Recent studies have identified NOTCH2NLC repeat expansions in patients with Parkinson's disease (PD) and atypical parkinsonism (aPM), suggesting ...
Han‐Lin Chiang, Kang‐Yang Jih, Cheng‐Tsung Hsiao, Fu‐Pang Chang, Justus Chunyu Chen, Yi‐Chu Liao, Yih‐Ru Wu, Yi‐Chung Lee   +7 more
wiley   +1 more source

Functional Determinants and Evolutionary Consequences of Pleiotropy in Complex and Mendelian Traits. [PDF]

Mol Biol Evol
Barbitoff YA, Bogaichuk PM, Pavlova NS, Malysheva PV, Predeus AV.   +4 more
europepmc   +1 more source

Central Dysmyelination in SSADH‐Deficient Humans and Mice

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Succinic semialdehyde dehydrogenase deficiency (SSADHD) is an inherited metabolic disorder characterized by an accumulation of γ‐aminobutyric (GABA). In addition to its synaptic role as an inhibitory neurotransmitter, GABA also plays an important role in myelination.
Itay Tokatly Latzer, Henry H. C. Lee, Edward Yang, Cesar Alves, Mariarita Bertoldi, Caitlyn Fung, Spencer V. Steele, Eren Kule, Zijie Jin, Alexander Rotenberg, Jean‐Baptiste Roullet, Phillip L. Pearl   +11 more
wiley   +1 more source

Validation of a morphological hidradenitis suppurativa phenotype algorithm (HS-KAPPA). [PDF]

Br J Dermatol
Porter ML, Kumar AM, Kirimlishvili S, Snyder CL, Gibson RS, Kimball AB.   +5 more
europepmc   +1 more source

Enrichment of the lung microbiome with oral taxa is associated with lung inflammation of a Th17 phenotype

Nature Microbiology, 2016
L. Segal, J. Clemente, Jun-Chieh J. Tsay, Sergei B Koralov, B. Keller, Benjamin G. Wu, Yonghua Li, N. Shen, E. Ghedin, A. Morris, P. Diaz, Laurence Huang, W. R. Wikoff, C. Ubeda, A. Artacho, W. Rom, D. Sterman, R. Collman, M. Blaser, M. Weiden   +19 more
semanticscholar   +1 more source

The rs10191329 Risk Allele Is Associated With Pronounced Retinal Layer Atrophy in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To investigate whether the rs10191329 risk allele in the DYSF–ZNF638 locus, which is implicated in central nervous system resilience rather than immune‐mediated pathology, is associated with retinal layer thinning, a biomarker of neuroaxonal damage in relapsing multiple sclerosis (RMS). Methods From a prospective observational study,
Gabriel Bsteh, Ruchi Tanavade, Nik Krajnc, Fabian Föttinger, Theresa König, Martin Krenn, Lukas Haider, Barbara Kornek, Fritz Leutmezer, Kerstin U. Ludwig, Stefan Macher, Tobias Monschein, Markus Ponleitner, Paulus Rommer, Christiane Schmied, Karin Zebenholzer, Tobias Zrzavy, Gudrun Zulehner, Franziska Di Pauli, Axel Schmidt, Harald Hegen, Berthold Pemp, Thomas Berger   +22 more
wiley   +1 more source