Results 61 to 70 of about 1,424,637 (273)

Large-scale albuminuria screen for nephropathy models in chemically induced mouse mutants [PDF]

, 2005
Background/Aim: Phenotype-driven screening of a great pool of randomly mutant mice and subsequent selection of animals showing symptoms equivalent to human kidney diseases may result in the generation of novel suitable models for the study of the ...
Aigner, B., de Angelis, M. H., Klempt, M., Rathkolb, B., Tran, T. V., Wanke, R., Wolf, E.   +6 more
core   +1 more source

Outcomes and Surgical Management of Malignant Rhabdoid Tumor of the Kidney: A Report From the Pediatric Surgical Oncology Research Collaborative

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Malignant rhabdoid tumor of the kidney (MRTK) is a rare, aggressive tumor seen in young children. The optimal timing of resection for locally advanced tumors is not well‐defined. The purpose of this study is to evaluate modern oncologic outcomes and the impact of surgical timing. Methods A multicenter retrospective review was performed
Hannah N. Rinehardt, Elisabeth T. Tracy, Anghela Paredes, Catherine Beckhorn, Harold J. Leraas, Joseph Fusco, Katlyn G. McKay, Nelly‐Ange T. Kontchou, Zachary J. Kastenberg, David W. Hoyt, Jonathan Roach, Emily K. Myers, Nicholas G. Cost, Bhargava Mullapudi, Charles R. Marchese, Amanda R. Jensen, Timothy B. Lautz, Michela Carter, Roshni Dasgupta, John Lundstedt, Joseph G. Brungardt, Lindsay Talbot, Andrew M. Davidoff, Andrew J. Murphy, Jennifer H. Aldrink, Sara Mansfield, Nelson Piche, Annie Le‐Nguyen, Dave R. Lal, Brian T. Craig, Jennifer M. Schuh, Barrett P. Cromeens, Sindhu Mannava, Shannon Castle, Adriana Lopez, Kelsey Mello, Joshua Short, Robin T. Petroze, Shay Rajaval, Grace R. Thompson, Peter Mattei, David H. Rothstein, Elizabeth Fialkowski, Kathryn Fowler, Nathan Martchenke, Barrie S. Rich, Richard D. Glick, Erin G. Brown, Kathleen Doyle, Paige Abril, Natashia Seemann, Jacob Davidson, Claire A. Wilson, Hau D. Le, Devashish Joshi, Michael Stellon, Tamer Ahmed, Alexandra Dimmer, Peter F. Ehrlich, Maya Hammoud, Keyonna Williams, Christa N. Grant, Merit Gorgy, Stephanie F. Polites, Julia Debertin, Danielle B. Cameron, Alyssa Stetson, Eugene S. Kim, William G. Lee, Aaron Barkhordar, Mary Austin, Brian A. Coakley, Anastasia Kahan, Joseph T. Murphy, Michael Pitonak, Chloé Boehmer, Marcus M. Malek   +76 more
wiley   +1 more source

Assessing Phenotypic and Genotypic Resistance to Flumethrin in Varroa destructor Populations in Muğla, Türkiye

Insects
Beekeepers use a variety of methods to control Varroa destructor (varroa). Chemical control relies heavily on flumethrin, amitraz, coumaphos, and tau-fluvalinate products.
Ali Sorucu, Bekir Çöl, Esra Dibek, Anara Babayeva   +3 more
doaj   +1 more source

Negative phenotypic and genetic associations between copulation duration and longevity in male seed beetles [PDF]

, 2009
Reproduction can be costly and is predicted to trade-off against other characters. However, while these trade-offs are well documented for females, there has been less focus on aspects of male reproduction.
AA Hoffmann, B Zwaan, C Mühlhäuser, CW Fox, D Houle, D J Hosken, D Reznick, DA Dewsbury, DA Roff, DA Roff, DJ Hodgson, DJ Hosken, DJ Hosken, DS Falconer, E A Brown, FJ Messina, G Arnqvist, GA Schwarzenbach, GJ Kenagy, HS Crudgington, IT MacBean, J Hunt, J Hunt, JS Kotiaho, L Gay, L Partridge, LW Simmons, LW Simmons, M Ackermann, M Edvardsson, M Edvardsson, M Gasser, M Lynch, M Tatar, MD Tuttle, ME Czesak, MH Gromko, MJG Gage, MJG Gage, MR Rose, MT Siva-Jothy, N Wedell, NG Prasad, OY Martin, OY Martin, P E Eady, P Eady, PE Eady, R Thornhill, R Vasudev, S Paukku, S Pitnick, S Wigby, S-B Horng, T Burk, T Chapman, T Clutton-Brock, T Miyatake, T Price, T Tregenza, TA Mousseau, UM Savalli, UM Savalli, UM Savalli, WA Becker, WA Van Voorhies, WG Hill, WJ Bailey, WU Blanckenhorn, Y Qi   +69 more
core   +1 more source

Adjunctive Therapeutic Plasma Exchange in Refractory Adult‐Onset Still's Disease Complicated by Secondary Macrophage Activation Syndrome: A Single‐Center Experience

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Adult‐onset Still's disease (AOSD) complicated by macrophage activation syndrome (MAS) carries substantial mortality. The role of therapeutic plasma exchange (TPE) remains uncertain. Methods We retrospectively analyzed patients with AOSD‐MAS treated with TPE at a single‐center.
Masataka Ueda, Tomohiro Saito, Masahide Mizobuchi, Tomoki Shimomura, Saki Kawamori, Mitsuru Kawanishi, Natsuko Hattori, Jo Sugiyama, Satoshi Tsubata, Hanami Horiguchi, Kazuki Abe, Nao Iida, Yuki Kajio, Nao Oguro, Ryo Yanai, Hirokazu Honda   +15 more
wiley   +1 more source

Evolution Equation of Phenotype Distribution: General Formulation and Application to Error Catastrophe

, 2006
An equation describing the evolution of phenotypic distribution is derived using methods developed in statistical physics. The equation is solved by using the singular perturbation method, and assuming that the number of bases in the genetic sequence is ...
A. E. Mayo, A. Kashiwagi, E. Akin, E. Baake, H. A. Orr, H. Haken, H. Risken, J. F. Crow, J. Hofbauer, John G. Kemeny, K. Kaneko, Katsuhiko Sato, Kunihiko Kaneko, M. S. Waterman, N. G. van Kampen, P. M. Morse, R. E. Lenski, S. Kauffman   +17 more
core   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Genetic and phenotypic characterization of the native rabbits in Middle Egypt [PDF]

Veterinary World, 2018
Aim: Native rabbits in smallholder system are considered as important genetic resources, and the present study was aimed to study the genetic and phenotypic characterization and detection of the maternal origin of the native rabbit populations located at
El-Sayed Mahfouz Abdel-Kafy, Sahar Saad El-Din Ahmed, Amira El-keredy, Neama Ibrahim Ali, Sherif Ramadan, Ahmed Farid   +5 more
doaj   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Digital Phenotyping

, 2022
This thesis is centered around the development and application of a digital platform for passive behavioral human subject research.This platform named Behapp (https://behapp.com), developed at the University of Groningen, makes use of mobile ‘apps’ to passively record various attributes related to social and explorative behavior through the smartphones
openaire   +2 more sources