Results 41 to 50 of about 173,452,781 (258)

Correlation Coefficient and Coefficient of Variation of the Ratio of Two Variables [PDF]

open access: yes, 1963
3 pages, 1 article*Correlation Coefficient and Coefficient of Variation of the Ratio of Two Variables* (Choi, K.) 3 ...
Cornell University. Dept. of Biological Statistics and Computational Biology.   +3 more
core   +5 more sources

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Phenotypic variation of traits.

open access: yes, 2016
Phenotypic variation of traits.
Hiroshi Tsunematsu (3176859)   +12 more
core   +1 more source

Phenotypic variability analysis of key sorghum (Sorghum bicolor (L) moench) genotypes under dry lowland areas

open access: yesReproduction and Breeding
Sorghum is a climate-resilient food security and nutrition crop, which has been produced as a staple food in the semi-arid tropical regions of the world.
Temesgen Begna
doaj   +1 more source

Phenotypic variability and genetic diversity analysis of cultivated potatoes in China

open access: yesFrontiers in Plant Science, 2022
Phenotypic evaluation and molecular biotechnology are both important in the identification and utilization of crop germplasm resources. In this study, the phenotypic variation and genetic diversity of 149 main potato cultivars in China were investigated ...
Jun Hu   +8 more
doaj   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

Trait means, genetic variance (VG), total phenotypic variance (VP), heritability (H2), and coefficient of genetic variation (CVG) in titre and mortality following KV infection in the DGRP.

open access: yes, 2018
Trait means, genetic variance (VG), total phenotypic variance (VP), heritability (H2), and coefficient of genetic variation (CVG) in titre and mortality following KV infection in the DGRP.
Nathan C. Medd (5334884)   +3 more
core   +1 more source

Glacial history affected phenotypic differentiation in the Alpine plant Campanula thyrsoides [PDF]

open access: yes, 2013
Numerous widespread Alpine plant species show molecular differentiation among populations from distinct regions. This has been explained as the result of genetic drift during glacial survival in isolated refugia along the border of the European Alps ...
Scheepens J. F.   +14 more
core   +2 more sources

Phenotypic Variation Analysis and Excellent Clone Selection of Alnus cremastogyne from Different Provenances

open access: yesPlants, 2023
Alnus cremastogyne is a rapidly growing broad-leaved tree species that is widely distributed in southwest China. It has a significant economic and ecological value.
Yue Zheng   +12 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

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