Results 141 to 150 of about 8,412,468 (340)

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Study and evaluation of correlation techniques for automotive sensor data [PDF]

, 2023
openI sistemi di guida completamente autonomi sono dotati di avanzati sensori in grado di rilevare e riconoscere rapidamente oggetti nell'ambiente circostante.
POZZEBON, MATTEO
core  

Associations between metabolic rate and personality in a free-living small mammal are driven by date of birth

Royal Society Open Science
Physiological states are often regarded as drivers of personality differences, although the causal link between them remains unclear. Studies focusing on energy metabolism often report inconsistent associations with personality traits.
Jingyu Qiu, Carsten Schradin, Astolfo Mata, Neville Pillay, Heiko Rödel   +4 more
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Direct-seeded rice as a promising approach for sustainable rice cultivation: multi-trait evaluation and selection of adapted genotypes

Frontiers in Agronomy
IntroductionRice acts as a staple cereal food for most of the Asian population. Interruption of climate change, water requirements, and labour shortages affect the cultivation of rice.
R. Praveen, V. Krishnan, D. Umamaheswari, Pasoubady Saravanane, Saminadane Thirumeni, M. K. Sakthi Anand, K. Preetha, J. Arathi, A. Shivada, Adavi Lakshmi Nikhil   +9 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Phenotypic factor and image analysis of type traits of holstein cows in the masstock Saudi herds

, 1995
Factor and image analysis were carried on 13,642 type traits records collected from Masstock dairy farms in Saudi Arabia. Principal component analysis showed that only 5 principal components (PC) were to be retained for factor analysis. These 5 principal
Ali, A.K.A., Al-Enazi, M., Al-Saidy, M., Hayes, E.   +3 more
core  

Phenotypic Correlations Between External Egg Quality Traits in Native Ducks and Geese

Contemporary Agriculture
The aim of this research was to evaluate the phenotypic correlations between external egg quality traits in native duck and goose populations reared in Bosnia and Herzegovina.
Vekić Marinko, Jovičić Marija
doaj   +1 more source