Results 131 to 140 of about 8,412,468 (340)

Comparison of Genotypic and Phenotypic Correlations: Cheverud’s Conjecture in Humans

Genetics, 2018
Cheverud’s conjecture asserts that the use of phenotypic correlations as proxies for genetic correlations in situations where genetic data is not available is appropriate. Although empirical evidence for this has been found across...
Sebastian M. Sodini, K. Kemper, N. Wray, M. Trzaskowski   +3 more
semanticscholar   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Phenotypic Correlation between Guard Hair and Down Hair in Chinese Alashan Left Banner White Cashmere Goat: A Preliminary Study. [PDF]

Animals (Basel), 2023
Pallotti S, Pediconi D, Valbonesi A, Renieri C, Haizhou S, Junwen Z, Antonini M.   +6 more
europepmc   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Phenotypic and Genetic Correlation of Cognition, Affect, and Brain Morphometry

, 2019
Background: Cognition is marked by complex cognitive processes and can be quantifiedusing intelligence constructs. On the other hand, affect is an indistinct construct,seemingly happening subconsciously and difficult to quantify (Newell & Shanks, 2014 ...
Kraljevic, Nevena
core   +1 more source

Patterns of phenotypic covariation and correlation in modern humans as viewed from morphological integration [PDF]

, 2003
Proportionality of phenotypic and genetic distance is of crucial importance to adequately focus on population history and structure, and depends on proportionality of genetic and phenotypic covariance.
Van Der Molen, Silvina, Hernández, Miquel, González José, Rolando, Miquel Hernández, Silvina Van Der Molen, Rolando González‐José, Emili González‐Pérez, González Perez, Emili   +7 more
core   +1 more source

The Cyp2b6 Gene Polymorphism and Phenotypic Correlation of Efavirenz-Based Combination Therapy Among the Niger Delta Ethnic Population: Implications in Modern Pharmacogenomics. [PDF]

Pharmgenomics Pers Med, 2022
Bunu SJ, Owaba ADC, Vaikosen EN, Ebeshi BU.   +3 more
europepmc   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Correlation between CD4⁺ T cells and phenotypic markers.

, 2013
NDGs were isolated from the blood of HIV+ patients (n = 21) as described in materials and methods and the expression levels of phenotypic markers were determined by flow cytometry.
Tom Cloke (102046), Shanthi Herath (123884), Manuel Modolell (59010), Graham Taylor (241206), Pascale Kropf (59011), Ingrid Müller (59004), Markus Munder (59009), Philip Bergin (455930)   +7 more
core   +1 more source

Genetic Variation, Heritability, Phenotypic and Genotypic Correlation Studies for Yield and Yield Components in Promising Barley Genotypes

, 2011
Eighty six promising new barley genotypes and three checks including one indigenous cultivar (Hordeum vulgare L. var Rum) were grown in two successive seasons of 2005 and 2006 to assess the presence of variability for desired traits and amount of ...
Jalal A. Al-Tabbal, A. H. Al-Fraihat
semanticscholar   +1 more source